Antoine Dusséaux

Entrepreneur. Previously @Doctrine (acquired by @SummitPartners).

Quaerendo invenietis: The Truth Will Set You Free

[Matt Spence @matthewswspence]

What I find most notable about this chart is that at its peak the US nuclear buildout was actually faster than the current Chinese one. If we could do that 50+ years ago we should be able to do much better today.

[Antoine Dusséaux @ADssx]

@OurWorldInData For Greenland Wikipedia says: "Same-sex marriage became legal on 1 April 2016." https://t.co/F6fHI5D4Km

[Antoine Dusséaux @ADssx]

.@SemiAnalysis_ describes the invisible output of AI. What about the dark "drag" / negative externalities / spam?

For instance, when I want to buy something, my agent contacts more businesses to request quotes than I used to do by myself. Sometimes I feel like I'm wasting their time. That's value destroyed for those businesses.

[SemiAnalysis @SemiAnalysis_]

AI Dark Output: The Visible Cost of Invisible Output
Why AI's increasing output is going to be one of the hardest economic measurement problems in history.
AI "Dark Output" could end up being the majority of economic activity, but a challenge to measure.
https://t.co/gYQz4WIvQg

[Antoine Dusséaux @ADssx]

@SemiAnalysis_ https://t.co/6hqv8lGqFX

[Antoine Dusséaux @ADssx]

Cost of a basic testament, 1600–2026, @SemiAnalysis_

[Antoine Dusséaux @ADssx]

@akarlin @UBERSOY1 Philosophy: no 🏴󠁧󠁢󠁳󠁣󠁴󠁿?

[Krister Kauppi - Rapamycin Longevity Lab @KristerKauppi]

The largest-ever lifespan analysis of 601 mTOR modulators is now completed! This project has been driven by Rapamycin Longevity Lab (@omipalRLL) in partnership with @OraBiomedical (CEO @benblueAK, CSO Yan Ting Zhao, AI Engineer Ishan Ranasinghe, Co-founders @mkaeberlein , @BKennedy_aging, @mitchellblee33, @jangruber467 & Jason Pitt). Our mission has been to identify compounds even more potent than Rapamycin in extending lifespan in roundworms.

I am deeply grateful for the community’s support for this historic project and big thanks to all our sponsors who made this possible!

Our Gold Sponsors:
✅ Melissa Burdick & Brian Burdick: Great tech leaders and e-commerce pioneers. Connect with Brian and Melissa on LinkedIn to follow their work.
✅ Antoine Dusséaux: A London-based entrepreneur. Connect with him on X via @adssx
✅ Dmitry Sadovnikov: Connect with him on LinkedIn or X via @ksajxai
✅ Ciarán Murray: A longevity enthusiast and tech founder of @OlasProtocol. Connect with him on X via @C1aranMurray
✅ Anonymous: Two anonymous contributions to the project and one by Anonymouse.

Other Sponsors of the Project:
✅ @agelessrx_ : A cutting-edge telemedicine platform specializing in making various longevity interventions accessible, actively involved in research and clinical trials.
✅ Winslow Strong: Dedicated to advancing human health and wellbeing. Follow him on X @winslow_strong.
✅ Dr. Grant Fraser: Specializes in longevity medicine, integrating lifestyle interventions with personalized medical treatments.
✅ @OpenCuresOrg: A unique online platform empowering individuals, health professionals, labs, and researchers to accelerate longevity interventions.
✅ Revi Health (@johanhedevag): Modern clinic in Sweden combining regenerative medicine, performance health, and longevity protocols for measurable results.
✅ @healthspanmed: The first-ever digital medical clinic helping patients fight cellular senescence and regain control over the levers of aging.
✅ Rapamycin Longevity Lab (@omipalRLL): Our mission is to become the leading expert around mTOR inhibitor-based combinational therapies for longevity.
✅ People in the longevity community: Thank you for every donation, like, and share. Your support has fueled this project!

PS 1: Big thanks also to Victor Björk for the help with the fundraising!

PS 2: All lifespan data is now available on the Rapamycin Longevity Lab’s LID database (link in the comment section). You can find the top 20 and bottom 20 lists right here in the social media image! Big thanks to Andrew Steele (@statto) for the great suggestion to create a bottom list as well!

PS 3: The next step is to collaborate with different parties to analyze the data and also see if the data translates to other species. Reach out if you want to collaborate!

[Antoine Dusséaux @ADssx]

@cremieuxrecueil "no increase in the risk of Lewy body dementia" => But Brennan and Tinworth 2025 conclude "Lewy body dementia (OR 1.32, 95% CI 1.23–1.41)".

[Hugo @lowlandsapien]

Throwing this into the accent arguments
You can hear British, American and Australian within individual sentences in this clip about Jersey vs Guernsey

[Antoine Dusséaux @ADssx]

Emerging markets run on WhatsApp: groceries, bookings, tradesmen, services, even banking.

Many businesses never built websites or apps.

With AI agents, what looked like a defect becomes an asset: give your agent WhatsApp access through wacli, and it can operate through the interface everyone already uses.

No APIs. No slow and buggy browser use.

Emerging markets may leapfrog web 2.0 straight into the agentic era!

[Paul Graham @paulg]

It was the best of times, it was the worst of times.

[Samuel Hume @DrSamuelBHume]

One of the most amazing things I’ve ever seen: a standing ovation for the full Daraxonrasib results

I feel inspired and energised, to put it mildly — we have a targeted therapy for pancreatic cancer now, and nothing is undruggable anymore

[Kamil Galeev @kamilkazani]

In a footnote to Capital, Marx brought up a testimony of a French worker. In France, he assumed he could do just one specific type of job (= printing). In California, he discovered that he in fact can do anything & all the constraints he faced in Europe were purely artificial

[Antoine Dusséaux @ADssx]

The aristocracy had to rely on large numbers of people for labor and military manpower. Those masses demanded concessions, diluting pure merit-based hierarchies.

Q: Do AI and robotics change the equilibrium?

[Marko Jukic @mmjukic]

I mean, it's a good question. Why hasn't human civilization naturally developed into a brutal aristocracy of the highly moral and high-IQ? Why don't we have a global "130 IQ high-trust Anglo" paradise already?

What mysterious force obviously overcomes and beats intelligence?

[Nathan Benaich @nathanbenaich]

uk: no data center
france: a lotta data center

[Joe Lonsdale @JTLonsdale]

1/ US biotech is in crisis, right before AI should be saving millions.

China is stealing away our industry and has surpassed the US in blockbuster pharma deals.

The next FDA Commissioner must be a fighter, and have a plan to overhaul the agency, beat China, and unleash cures.

[Antoine Dusséaux @ADssx]

Talking French to AI feels like coding in Latin.

[Marc Andreessen 🇺🇸 @pmarca]

Legal AI superempowers normal individuals with no legal background to fight big institutions in bureaucracies and in courts on a level knowledge/skill playing field, for the first time in human history. As such, it is one of the most inspiring applications of AI.

[François Chollet @fchollet]

Did you think about the Roman empire today?

[Epoch AI @EpochAIResearch]

We took another look at the capability gap between open-weight and proprietary models. Since the start of the year, open-weight models have lagged the state of the art by four months.