Excited to share our latest work published today in @NatImmunol! 🎉 Together with Taja Vatovec, we investigated how somatic CBL deficiency affects B cell development and function. https://t.co/sROc3oMXX2
Decades of research have revealed the intricacies of how dendritic cells (DCs) function, but fundamental questions remain about how this group of cells develops in humans and how this process goes awry in disease. A thread on our new work! (1/9)
https://t.co/9hgDt3r8n1
🩸🧬 Dendritic cells are rare but key players in immunity. In a new preprint led by @CohnOfir, we generate a single-cell multi-omic atlas of human dendritic cell differentiation to reveal links to immune-mediated disease: https://t.co/4Q8pA0SykL
Excited to share our latest work published today in @NatImmunol! 🎉 Together with Taja Vatovec, we investigated how somatic CBL deficiency affects B cell development and function. https://t.co/sROc3oMXX2
What protects some people from leukemia?
Thrilled to share work from the @bloodgenes lab, now published in @Science.
We identify an inherited genetic variant that protects stem cells from blood cancers by reducing risk of CHIP.
https://t.co/ExgWIJQe6y
🧵👇 (1/n)
1/n 📢 🚨 Excited to share that our latest findings from @bloodgenes lab is now out in @NatureCellBio! We discovered that #ferroptosis is a key barrier to #HSC survival during ex vivo culture. 👇Here is the story 👇
https://t.co/US3IoJZB1p
Attending #ASHG2025 in Boston! Excited that my first PhD student Matthieu @MChaldebas was selected for a presentation on our work detecting 5′UTR variants impacting translation. Great to have @casanova_lab crew here - Clement, Astrid, Gaspard @GaspardKerner, and Anna @ALNeehus.
PhD position opening in my lab! Grab your chance to dive into the genetics and pathophysiology of inborn errors of immunity and apply!
@FWOVlaanderen @ERC_Research @Info4PI @KU_Leuven funded, in an international spirit. https://t.co/ACMP5dIDMn
Latest from us. Universal antiviral made! How? Transient gene therapy. Which genes? Only 10 suffice, out of thousands of antiviral host genes. How did we choose? Got inspired by patients and gene promoters. Read in detail 👇🏼 https://t.co/uhuhvbZ5KK
1/ Join us on 24 Sept 2025 at the @InstitutImagine in Paris for the Novo Nordisk Prize Symposium: Inborn Errors of Immunity. Registration is free at: https://t.co/eBCD1HjwGf
Delighted to have our preprint led by @lvchosen1 up: Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
https://t.co/nMP5Xd7aEY
🧵 below ...
Very happy to share our review @bloodgenes published today in JHI. We discuss how rare and common genetic variants influence early B cell development and can underlie susceptibility to infectious diseases, autoimmunity and leukemia. 🔬🧬
.@ALNeehus, Neil Romberg, and @bloodgenes review how genetic variation impacts early B cell development, & discuss inherited rare variants & more common polymorphisms that predispose to B cell-related immune disorders & malignancies https://t.co/X80Z4ZB8IR
1/ We are delighted to share our work published in @SciImmunolgyidentifying the role of LY9 in CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis
(https://t.co/30GP2g4st4)
Thousands of GWAS hits—but how do we link them to biology? 🚨New from Alkes Price group: J-PEP integrates pleiotropy and epigenomic data to reveal shared disease mechanisms across diseases https://t.co/STMgkpoOKl #genomics#Statistics@HarvardChanSPH