Anu Suomalainen-Wartiovaara Lab

Mission: Understand the molecular background of mitochondrial disorders to develop diagnosis and therapy.
(managed by lab members)
@STEMMprogram @helsinkiuni

[Juan Cruz Landoni @jclandoni]

Stoked to share TWO preprints on mitochondrial pearling! 🎉
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (https://t.co/Q9OcuMZBvH), and @sturm_gav et al. dissect the biophysics behind it (https://t.co/qIVsxYiXDh). Details below! 🔬🧵

[Juan Cruz Landoni @jclandoni]

Time for a short explicative 🧵 for the busy 🐝!

In our new report (#OA: https://t.co/aNzPpZgiai) we found that enhancing #mtDNA replication can be deleterious for newborn #heart, causing dilated #cardiomyopathy & #ferroptosis 🫀

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[Anu Suomalainen-Wartiovaara Lab @ASW_lab]

ASWlab's Rohit Verma & @marmyleva_ana together with @Elstar4stars talk about #mito in research and patient care in @SciBasementPod podcast episode: https://t.co/W7Y5sMQZdY
#lightupformito

[Anu Suomalainen-Wartiovaara Lab @ASW_lab]

The PolG Foundation supports mitochondrial disease research. The Foundation's short film describes how the disease affects the lives of patients and their families.

The PolG Foundation Film https://t.co/7KZksDHzh0 via @YouTube

[Anu Suomalainen-Wartiovaara Lab @ASW_lab]

PolG Foundation tukee mitokondriosairauksien tutkimusta. Säätiön lyhytfilmi kuvaa koskettavasti kuinka sairaus vaikuttaa potilaisiin ja heidän läheisiinsä. (Video vain englanniksi)

The PolG Foundation Film https://t.co/7KZksDHzh0 via @YouTube

[Riikka Kivelä @Kivela_lab]

Fantastic work and exciting findings by @jclandoni and @ASW_lab👇

[Anu Suomalainen Wartiovaara @AWartiovaara]

High mtDNA replication frequency is deleterious for newborn heart, causing dilated cardiomyopathy & ferroptosis. Our paper out in @NatureComms, outstanding work by @jclandoni. Thanks for crucial results @seminerkul @ASW_lab @HelsinkiUniMed @helsinkiuni
https://t.co/Ly8mLYDn1d

[Anu Suomalainen Wartiovaara @AWartiovaara]

Very happy to share our new article of the interaction of mitochondria, innate immunity and viral infections and the relevance for brain &liver disease. Impressive work by @KangYilin. Thanks @hepojoki @Olli_Vapalahti and all collabs! @helsinkiuni @ASW_lab https://t.co/KIo0L2cUsz

[MetaStem @MetaStem_Center]

Metabolism Seminar time again next week March 26th at 9-11 in Biomedicum. Exciting talks from @OorniLab and @ASW_lab on lipoproteins, atherosclerosis, mitochondrial disease and mtDNA replication ☕️🍪at 8:30,Welcome! @HelsinkiUniMed @STEMMProgram @LifeSciHelsinki @HiLIFE_helsinki

[Anu Suomalainen Wartiovaara @AWartiovaara]

Thank you JCB for selecting our article on metabolic ciliopathy of astrocytes as one of the 10 highlights of 2023 in the journal’s special issue ”Year in Cell Biology” @ignatenkolesya @GulayseDunn @HelsinkiUniMed @helsinkiuni @STEMMProgram @ASW_lab @HiLIFE_helsinki

[Anu Suomalainen Wartiovaara @AWartiovaara]

Tänään @HelsinkiUniMed mitokondriotautipäivä, Biomedicum Helsinki ja zoom. Lauantaina vihreät rakennukset Australiasta Suomeen ja Amerikan mantereelle muistuttavat potilaiden viestistä: toivo on tutkimuksessa. @helsinkiuni

[Anu Suomalainen-Wartiovaara Lab @ASW_lab]

Tule mukaan avoimien ovien MitoPäivään torstaina 21.9. klo 15:00 alkaen Biomedicumissa ja webinaarissa.
Lisätietoja: https://t.co/Lq6zWBxYGw
#WorldMitoWeek #LightUpForMito

[Anu Suomalainen-Wartiovaara Lab @ASW_lab]

Join us for Mitochondrial Disease Open Doors on Thursday 21 Sept at 15:00 (GMT+2) on site or remote!
Further details: https://t.co/gYALUxy7UM
#WorldMitoWeek #LightUpForMito

[The Science Basement Podcast @SciBasementPod]

#WorldMitoWeek is upon us! Rohit Verma joins us to explore the intricacies of mitochondrial disorders, patients' daily challenges, and treatments to manage these conditions.
SoundCloud https://t.co/tfMXATVhaS
Spotify https://t.co/N4wfMmwGmw
ApplePod https://t.co/fPSbTgPiip

[Anu Suomalainen Wartiovaara @AWartiovaara]

Mitä ovat mitokondriotaudit? #WorldMitoWeek avoimien ovien MitoPäivä Biomedicumissa, 21.9. klo 15-18. Tule tutustumaan mitokondriotauteihin ja niiden tutkimukseen, potilaiden ja perheen kertomuksiin, kuulemaan lääkärien ja @neuroliitto asiantuntemusta.
https://t.co/HROcdAU5uN

[Anu Suomalainen Wartiovaara @AWartiovaara]

For the #WorldMitoWeek @ASW_lab @HTyynismaa and @FhrcGracile are organizing an open doors day, with scientists, patients & families, doctors and @neuroliitto patient union talks. 21.9. at 15-18 EET. In Finnish, translated to English in zoom. Follow link: https://t.co/5153Iz47v5

[Anu Suomalainen Wartiovaara @AWartiovaara]

Being a scientist is the best job. When the lab becomes silent on Friday evenings, the ideas from the past week start to get together and bubble. Alone in the office, content and energized. So happy to work with you all @ASW_lab!

[Anu Suomalainen Wartiovaara @AWartiovaara]

Very excited to follow the entry of the 1-yr-old startup @NADMED_Ltd to USA market via partnering with @TruDiagnostic. NADMED is an innovation that was initiated in my @ASW_lab developed by docent @LiliyaEuro. https://t.co/q4GUhijJNA

[Journal of Cell Biology @JCellBiol]

Our January cover shows a scanning electron microscopy micrograph of ependymal cells lining the surface of a mouse brain ventricle. From @ignatenkolesya et al @ASW_lab (https://t.co/KP5IF2p3YL). Read JCB’s January Issue: https://t.co/u7xmrNC6x9

[Olesia Ignatenko @ignatenkolesya]

Mitochondrial dysfunction in CNS manifests with neurodegeneration and reactive gliosis, traditionally explained by vulnerability of [their majesty] neurons. We thought it may not be the full story... and found critical astrocyte contribution to the pathology! 🤓 1/