Aaron Holling

PhD candidate in the Olejniczak lab at Roswell Park. Studying RNA biology in T cells.

[Olejniczak Lab @LabOlejniczak]

Thrilled to share the lab’s first preprint, a really great story about how CD28 activates a novel regulator of alternative splicing in order to reprogram T cell metabolism led by ⁦@RoswellParkPhD student⁩ ⁦⁦⁦@AaronHolling⁩ https://t.co/LoiWPzGHfo

[Kimberly Luddy @luddyka]

In this paper we show that lymph nodes are acidic and these acidic niches keep the T cells calm while in the LN.

Like many others, this paper has a cool backstory. I promised to share it so enjoy the thread if you are interested. (1/n) #immunology

https://t.co/YklmLTSMNS

[Jason Locasale @LocasaleLab]

Figures for an upcoming review on metabolism and chromatin

https://t.co/oZJHY4pSpd

[Olejniczak Lab @LabOlejniczak]

Happy to share our latest work: https://t.co/MQaAeVsITx

[Lydia Finley @lydfinley]

Celebrating an end to 2019 by anointing the "paper Lydia wouldn't shut up about in 2019" award:

[Russell Jones @DrRGJonesLab]

Please check out our new paper on using 13C tracing to study T cell responses in vivo. Amazing work by Eric Ma and a great collaboration with @AgiosPharma @RJDLab @jrfmricher and Connie Krawczyk https://t.co/x6kyUbjPiN @ImmunoMet

[Jason Locasale @LocasaleLab]

Our review now @NatureRevCancer. Methionine metabolism in cancer and health. Discussions on diet, our recent work couple papers, some cell biology and biochemistry, disease and cancer contexts.

https://t.co/qTjDWmcHNX

[Russell Jones @DrRGJonesLab]

For those interested in using our Bioenergetics tools for Seahorse analysis, please visit our website: https://t.co/qVS54xCLV3 Lots of fun tools to move beyond ECAR and OCR to characterize bioenergetic capacity #KSmetastasis @KeystoneSymp

[Immunometabolism Network @ImmunoMet]

One of the all-time great immunometabolism reviews: Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity @ImmunityCP #immunometabolism https://t.co/vOObm54GVR

[Taka Nojima @pol2rna]

Our new paper is out @MolecularCell online. #mNETMS and #mNETseq revealed catalytic spliceosome associated with Pol II CTD S5P for co-transcriptional splicing. Great collaboration with Carmo-Fonseca lab and @tomsgoms! https://t.co/Hq78JxXafB

[Lasker Foundation @LaskerFDN]

Robert Singer speaks about single #mRNAs within living cells and what these studies reveal about gene expression, translation, and the dynamics of #RNA degradation. https://t.co/k9p4ik3fTw @ibiology @EinsteinMed @RNASociety

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2018 #NobelPrize in Physiology or Medicine has been awarded jointly to James P. Allison and Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.”

[The RNA Society @RNASociety]

Beautiful. 😍💖💘