Ajit Kumar Maurya , PhD

@UoA_official Alumni, Research scholar at @IGIBsocial , RNPs and RNA structural Biology
- tweets are personal views.

[CSIR-IGIB @IGIBSocial]

Thukral and group at @IGIBSocial have shown in a recent publication that autophagy can be altered. Using simulations and experiments they show that lipid binding allosterically modulates the protein which in turn can be leveraged to tune the protein activity. The work has translational implications as autophagy is linked to several diseases including cancer.

Read here: https://t.co/0qYkRmg9Lk

@SouvikM29933298 @Sci_Lipi @CSIR_IND @Deepanshi_G @NatureComms @Jesucastin

[Lipi Thukral @Sci_Lipi]

Excited to share that our paper is now out @NatureComms. We engineered a previously unrecognised binding interface in LC3 to selectively alter autophagy receptor recognition.

More here: https://t.co/is0yuariXw

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

[The Nobel Prize @NobelPrize]

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.

The Nobel Prize laureates identified the immune system’s security guards, regulatory T cells, thus laying the foundation for a new field of research. The discoveries have also led to the development of potential medical treatments that are now being evaluated in clinical trials.

The hope is to be able to treat or cure autoimmune diseases, provide more effective cancer treatments and prevent serious complications after stem cell transplants.

#NobelPrize

[Biochemistry @BiochemistryACS]

Finding RNA features:

Rakheja et al report "TRIPinRNA," an in silico platform that searches for triplexes across the transcriptome, and validate several hits, including a structure previously thought to be unstable.

https://t.co/DC38OlzkVy

#RNA
@IGIBSocial
@AcSIR_India

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

@ThevoiceDeepraj @bwajtweeting Congratulations bro 🎉👏

[The Journal of Physical Chemistry @JPhysChem]

This research using ITC and MST revealed that sgRNA-Cas9 binding is driven by entropy, while CRISPR RNP-DNA interaction relies on favorable enthalpy. #CRISPR #GenomeEditing #Biotechnology #Thermodynamics @IGIBSocial @CSIR_IND @nxj046000 @souvik_csir
https://t.co/9DWJRNNBZ6

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

@mvdeshmukh Many Congratulations to the team 🥳🎈🎉

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

Thank you @nxj046000. This wouldn't have been possible without your constant guidance.

[niyati jain @nxj046000]

We our excited to share that our first paper is nominated among the very best papers published in Biochemistry (ACS) for 2023. It got as much attention that ACS asked for nomination of @Ajit_Kumar_RNA for Gordon Hammes Scholar award. It’s a proud moment for lab. All the best Ajit

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

@TNQTechnologies @DilipMenon10 Congratulations 🎉👏 well deserved 🥳

[CSIR-IGIB @IGIBSocial]

We kickstarted with a research poster presentation session which was followed by the Director's address to the newly formed Research Council.

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

@AkashPratap37 @CSIR_IND @IGIBSocial @AcSIR_India @MSJEGOI Congratulations Bravo 🎉👏🎉

[Bijnor Express @bijnorexpress2]

बिजनौर में वैज्ञानिकों ने बच्चों को लार में मौजूद डीएनए दिखाया। शिक्षकों ने की सीडीओ की पहल पर आयोजित कार्यशाला की सराहना।
#Bijnor #CSIR
@HRDG_CSIR @CSIRIndia
@dmbijnor @CdoBijnor
@KaurPrabh130 @talatazam95 @Ajit_Kumar_RNA
@GVRayasam
@PoortiKathpalia
@souvik_csir
@beena_tweets
@DrNKalaiselvi

[CSIR-IGIB @IGIBSocial]

Our outreach team visited Bijnor, UP on 16th October 2023.
The energy of the 350+ kids resonated with the energy of our super volunteers @KaurPrabh130 @talatazam95 @Ajit_Kumar_RNA
and Inderpreet as they saw their own DNA.

Contact our outreach team for a visit to your school!

@CsirJigyasa

[Poorti Kathpalia (She/her) @PoortiKathpalia]

On our way to Bijnor for @CSIR_IND Jigyasa Lab@Home event with a bunch of enthusiastic volunteers - Inderpreet, @talatazam95, Prabhleen and Ajit.
We are eagerly waiting to meet 350 students from various government schools of Bijnor, UP.

#scicomm #genomics #DNA #outreach

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

@sheetalgandotra Congratulations mam and to the entire team 💐💐💐👏

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

@ManishaKochar @foldingINvivo @IGIBSocial Congratulations 🥳💐

[niyati jain @nxj046000]

Curious minds !!! Part of OWOL open day at IGIB …

[CSIR-IGIB @IGIBSocial]

One Week One Lab inauguration is set to take place on September 18, 2023. We invite you to join us in this grand science gala where various stakeholders, including clinicians, industry professionals, students, and the general public, will come together at @CSIR_IND - IGIB.

We have some exciting events lined up for OWOL. Stay tuned for updates and don't miss out!

@PMOIndia @DrJitendraSingh
#OneWeekOneLab #IGIB #OWOLIGIB

[Ajit Kumar Maurya , PhD @Ajit_Kumar_RNA]

The multifaceted potential of #lncRNA

[CSIR-IGIB @IGIBSocial]

The August issue of Pulse is out and it is dedicated to RNA.

Visit https://t.co/v4bKXPb3ru to read some of the RNA stories by our research scholars -
@PriyankaMMehta and Ajit Kumar.

#RNADayIGIB #AUG #RNADay
@RajeshPandeyLab
@nxj046000 @PoortiKathpalia