Thanks to the @parkerici for funding a Career Development Award for the Perry Lab @sloan_kettering . Congrats to fellow recipients @David_Lab_MSK and @AlanHanash . We are all super grateful!
Immune cells target #stemcells in the destruction of intestinal lining cells that occurs before renewal. Research by @AlanHanash @sloan_kettering in @SciImmunology. Read more on https://t.co/k5t7eeCb4f with @MRC_LMS and @AntDLewis
Being a physician scientist is immensely rewarding. I come to the lab/clinic every day with a sense of wonder, joy, and anticipation. I support these efforts to keep this career path at the nexus of investigation and patient care alive. Pay it forward.
https://t.co/wv7q7DzMRb
7/10 PATHOPHYSIOLOGY: @AlanHanash and colleagues showed that IFN-g directly programs intestinal stem cells for apoptosis, and that the effect can be reversed by neutralizing Abs or JAK/STAT inhibition. Rux may influence tissue responses to inflammation. https://t.co/LK0kZ59jt0
In 2012, @AlanHanash published that IL-22 protects intestinal stem cells from immune-mediated damage in our interest turned into this cytokine as a potential therapeutic strategy to promote #mucosal#healing in #IBD patients.
DOI: 10.1016/j.immuni.2012.05.028
New article on pre-transplant serum levels of claudin-3 as a predictive biomarker for intestinal #GvHD and non-relapse mortality risk in patients undergoing allo-HSCT, now available on the @gvhd_hub ➡️ https://t.co/ZpTkOMJGf0 #bmtsm
The MSK Infectious Disease Service is recruiting a new clinical faculty member. Please apply if interested in joining a terrific faculty in New York City.
Many examples of T cells causing pathology in the gut during infection and role of IFN-g (best cytokine ever). How does IFN-g contribute? See cool paper on T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage https://t.co/DMBjqWU4Ai
Happy to be home in sunny NYC. Thanks to our amazing speakers @zhangf, Giuliana Ferrari, and Wendell Lim for making transplant/cellular therapies the best scientific session at #ASH2019 and one of the most attended!
Great discussion at the annual meeting of the #ASH19 Scientific Committee on Transplantation Biology and Cellular Therapies! This year our session #ASH2019 attracted more than 500 colleagues! Great job @AlanHanash, Cathy Wu, @MarcoLDavila @MarcelaMaus and many more!