Alex Legaria

Neuroscience Postdoctoral Fellow at @harvardmed

[Alex Legaria @AlexLegariaM]

@rgarciareyes4 @WUSTL @WUSTLmed @FlanBrain Congrats!!

[Alex Legaria @AlexLegariaM]

@jmourabarbosa @CosyneMeeting Congrats!!

[J. Simon Wiegert @SimWieg]

A thorough and thoughtful summary of the features and limitations of our fused fiber photometry system by @AlexLegariaM @LexKravitz
https://t.co/n8bw6xiSsA

[Bridget Matikainen-Ankney @bridge_balance_]

Latest paper exploring motivation in obesity and underlying NAc circuits from the @LexKravitz lab! This work was vaulted over the finish line by our incredibly talented undergrad @YiyanPan 🍔🍕🥯🐁

https://t.co/xjQAG7qlPH

[Alex Legaria @AlexLegariaM]

@LexKravitz Thank you for being a wonderful mentor @LexKravitz

[Alex Legaria @AlexLegariaM]

Also, all the raw data and data analysis pipelines are available at https://t.co/VEvzIRF9vn. Please feel free to reuse any of the code there.

[Alex Legaria @AlexLegariaM]

I’m excited to announce the latest paper from
@LexKravitz
lab in collab with @jones_g_parker lab. https://t.co/zId2q8JcS9. Here, we show that calcium fiber photometry in striatum reflects nonsomatic changes in calcium.

[Alex Legaria @AlexLegariaM]

On a final note, I’d like to give a shout-out to all the peer-reviewers both from the journal and here on twitter. Their feedback was incredibly helpful, and it really reshaped the paper to be what it is now.

[Alex Legaria @AlexLegariaM]

@neuronick_ @philJRDB @gavanm Thank you!

[Alex Legaria @AlexLegariaM]

Does anyone know of papers that analyze fiber photometry data in other way other than peri-event analysis or counting transients? If so, would you mind sharing refs?

[Alex Legaria @AlexLegariaM]

@nanopharmNC @Meaghan_Creed Yes, please!!

[Bridget Matikainen-Ankney @bridge_balance_]

The latest preprint from @LexKravitz lab is here!! We asked how obesity drives changes in NAc circuits and food seeking. 🍔🐭https://t.co/E2kWYwovjR

[Alex Legaria @AlexLegariaM]

@MikeChurchill19 Can I get some sample data?

[Alex Legaria @AlexLegariaM]

What features would you like to see in a python package for fiber photometry signal processing? I have a module that a few labs have found useful. I'm thinking about refining and expanding it, and to make it public. The emphasis is to make it as simple to use as possible.

[Alex Legaria @AlexLegariaM]

@MikeChurchill19 Interested!

[Puja Parekh, Ph.D. @_DrOctothorpe_]

Reminder from @AlexLegariaM that striatal fiber photometry signals do not reflect somatic firing activity in comparison with endoscopic recording and in vivo ephys. Interpret those traces with caution! #IBNS2021

[Bridget Matikainen-Ankney @bridge_balance_]

Our FED3 paper from @LexKravitz lab just dropped in @eLife!! With co-lead authors @mohamedamrali93 and the Untwittered Tom Earnest, this open-source platform allowed us to collect home cage food intake and operant behavior data across multiple institutes.
https://t.co/sNkl0SlLx8