Alis Olea

🔬PhD student @n4nlab
#superresolutionmicroscopy & #nanoparticles @IbecBarcelona

[Alis Olea @AlisOlea]

Happy to share that our long-awaited micelle article is finally published, proposing a simple 3D chip setup for assessing the mobility of polymeric micelles through the tumor ECM. Thank you so much @Fluo_renzo and @RoeyJAmir for the continuous support! https://t.co/wjYQUaPOp4

[Roey J Amir @RoeyJAmir]

Unlike books, together with @n4nlab (@Fluo_renzo) and @Hoogenboomgroup, we used Dendritic Amphiphiles with Different Hydrophilic Blocks for Judging Micelles by Their Covers https://t.co/1DxLye7C4G. Great Job @GadiSlor and @AlisOlea (@theracatEU)

[Nanoscopy for Nanomedicine lab @n4nlab]

🚨2021 came with an exciting publication from our lab: ‘Real-Time Ratiometric Imaging of Micelles Assembly State in a Microfluidic Cancer-on-a-Chip’ from @FgrNats & @a_mareska 👏🏼@AIMBiotech @RoeyJAmir @shirubianomono @Fluo_renzo @TUeindhoven @IBECBarcelona https://t.co/UCnWRIyByr

[Alis Olea @AlisOlea]

@NakedCapsid I've been designing my group's website (here, if you'd like to check: https://t.co/u0GUTlacv2 ), but for a personal one I keep having the feeling that there are too few things to put on it. Maybe it is time to do it 😄 Thanks for the encouragement!

[THERACAT project @theracatEU]

The first paper of @theracatEU project is out!👏👏👏 It’s about micellar disassembly and enzymatic degradation of amphiphiles. Check this nice piece of work lead by @RoeyJAmir with the participation of @shreyaswagle93
👇👇
https://t.co/ppA0ZPz05g

[Alis Olea @AlisOlea]

@theracatEU @BOOMchemistry 😍

[THERACAT project @theracatEU]

At @BOOMchemistry we use TMCs to release #prodrugs 💊 Preliminary, TMC activity can be measured over time with #fluorophores!! Today our #chemistree has been decorated with catalytically turned-on #prodye "cleavaBalls" 🎄 #Transition #Metal #Catalysis #bioorthogonal #chemistry

[Nanoscopy for Nanomedicine lab @n4nlab]

Our preprint on Quantitative nanomedicine is out! 💊🎯 great collaboration with Nick Tito to understand targeted nanomedicines using quantitative theoretical and experimental methods https://t.co/2ajlet0PRn @ADDReditors @wth_laura #nanomedicine #drugdelivery #multivalency

[THERACAT project @theracatEU]

Sprouting of mCherry EMT6 cells tumor spheroids shows the aggressiveness of BRCA mutated breast cancers. #3D #Biology #breastcancer #CancerResearch ⁦@RSFLab⁩ ⁦@AjamilR⁩

[THERACAT project @theracatEU]

Using super-resolution microscopy on nanoassemblies, we can unravel unprecedented details, showing the heterogeneity in molecule number and architecture on a single-particle level.

Here an image from previous research on polyplexes (scale bar 2 µm) 🔬

@AlisOlea @n4nlab

[Alis Olea @AlisOlea]

@theracatEU Before the training, I was actually thinking to buy one for myself, just for fun 😀 #whatmicroscopistsdointheirfreetime

[THERACAT project @theracatEU]

Funny how images of faraway galaxies look very similar to those of nanoparticles on a glass slide in widefield TIRF microscopy (the brighter ones are usually aggregates)✨🔬
@AlisOlea @n4nlab
#stargazing at the #nanoscale

[THERACAT project @theracatEU]

Amazing image of @biogelx gels structure 🤩

@AlisOlea @n4nlab
#confocalmicroscopy

[Alis Olea @AlisOlea]

My PhD is part of the #THERACAT consortium, developing bioorthogonal catalysis for cancer therapy. In particular, my project is about #imaging the delivery of #nanocatalysts and prodrugs to the tumor site.

[THERACAT project @theracatEU]

@theracatEU is based on innovative THERApeutic CATalysts science (1/2): materials bearing a catalytic unit are delivered to the #tumor and afterwards non-active prodrugs are administered to the patient and become active only in the sites where the catalytic units are functional

[Frontiers - Bioengineering and Biotechnology @FrontBioeng]

Interested in #medical and industrial applications of #microfluidic-based cell/tissue culture and #organs-on-a-chip?

Read and download this article collection here:
https://t.co/avsvyws97S

Lead by researchers from A*STAR, @DTUtweet and Academia Sinica

#toxicology #cellculture

[Nanoscopy for Nanomedicine lab @n4nlab]

🚨🎬Take a look at @a_mareska ‘s video describing her work on microfluidic technology facilitating drug screening that will be presented the 13th #IBECSymposium ‘Bioengineering for Future Medicine’ 27-28th OCT. Vote with a like to support! @IBECBarcelona
https://t.co/Dn7dXVNQmr

[Ilya Levental @LeventalLab]

An important problem that's way too often overlooked in single molecule or super-res studies is the potential influence of membrane topology.

Another contribution from Ingela Parmryd on this essential point: https://t.co/s4oEDki44w

[Nanoscopy for Nanomedicine lab @n4nlab]

🚨🚀We proudly present our new website! https://t.co/vMaScvjMC9 🥳🖥️ A platform to unify our group efforts delocalized between @IBECBarcelona and @TUeindhoven 📌 A special thanks to @AlisOlea for her beautiful design 😍

[Lorenzo Albertazzi @Fluo_renzo]

Our latest paper is out on BioRxiv! Great work of @FgrNats and @a_mareska that combined spectral imaging with organ-on-a-chip to track nanoparticles along their path towards cancer cells. Does your NP survive this voyage? Microscopy will tell you! @n4nlab
https://t.co/FdMcDi1ijI

[Nanoscopy for Nanomedicine lab @n4nlab]

❕❗️Be our new colleague! N4N is looking for a new PhD in Eindhoven that will work on superesolution microscopy to characterise nanoparticles 🧪🔬 RT please https://t.co/rBSiEOdHCJ