Ilya Levental

laboratory on structure and functions of living membranes lab at University of Virginia ; also posts occasional nonsense - views our own, not UVA

[Ilya Levental @LeventalLab]

It’s not every day that you get to share a story that you truly believe changes a paradigm!

Today is that day for us. We hope you agree: https://t.co/hdjV2KYETO

Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry

What's the big idea? Tweetorial below!
1/9

[The Company of Biologists @Co_Biologists]

Early-career researchers - applications are now open for funded places at our Workshop on Membrane Function: Insights from Cellular Diversity and Evolution, organised by Snezhana Oliferenko & @CunqiYeLab.
Find out more and apply https://t.co/bnmc531Zio
#BiologistsWorkshops #ECR

[jared toettcher @toettch]

Hey friends, we're hiring over here at Princeton BioE! In addition to the usual positions (faculty, grad students, postdocs), BioE is looking for a Program Manager to oversee big multi-PI projects (e.g. DARPA, ARPA-H). Pass along & apply if interested! https://t.co/6aoz23961c

[Matthew Eddy @MatthewEddyLab]

Our new preprint "Spatial Organization of Lipids Drives GPCR Conformational Equilibria" is now available at bioRxiv:
https://t.co/IYxE9nVYiO
Led by @anuradha_viraj, additional PhD trainees, and key collaborations with Ed Lyman and his postdoc Dr. Jingjing Ji.

[Karen Fleming @KarenFlemingPhD]

We need a BIG BEAUTIFUL RESPONSE to the horrible rule proposal that came down from OMB in late May that will kill science and the science ecosystem. Our #BigBeautifulResponse needs to have maximum impact. 1/8

@BiophysicalSoc

[Ilya Levental @LeventalLab]

Pretty cool!! https://t.co/jJBuzSTgjO

Last year, we showed that membranes can be asymmetric in an unexpected way: more phospholipids on one side than the other, balanced by cholesterol

Here, Bogdanov et al show similar in EColi, with DAG doing cholesterol's flippy-buffer job

[Ilya Levental @LeventalLab]

friends and scientists...

some simple descriptions of consequences of rule changes being proposed by the administration: https://t.co/sKveHT8G9O

If you think these proposals suck, please submit comments, its easy and quick, as explained at link.

[NEJM @NEJM]

Presented at #ASCO26:

Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq

@ASCO

[Max von Hippel @maxvonhippel]

By the way this is how you get into a PhD program. I applied to 6 programs. The 3 I got into (NEU, Duke, and UA) were the ones where I did exactly this for the specific prof at each I was interested in. The 3 I did not get into (UT Austin, Berkeley, MIT) were the ones where I did not do this.

[Thierry Ennui @TitiEnnui]

For Those Who Waited 22 Years.

[Arsenal @Arsenal]

This belongs to all of us.

[Biophysical Journal @BiophysJ]

#OPENACCESS: Clustering hinders APP α-secretase processing in the plasma membrane. Kerstin Pinkwart and Thorsten Lang. https://t.co/JJzYnDPkPI

[Ilya Levental @LeventalLab]

@OlzmannLab @RobertoZoncu @RapeLab @DanNomura what a group!!

[Vintage Maps @vintagemapstore]

Timeline of World War II

[Henne_Lab @HenneLab]

Summer is approaching & so is the 2026 Lipid Droplets: From Mechanisms to Disease FASEB SRC (July 26-30 in Scottsdale, AZ)!

Interested in lipids? Join this amazing summer research conference!

Abstracts due May 31,
Early registration June 14.

https://t.co/G6tAlhSxUF

[Jeremiah Johnson 🌐 @JeremiahDJohns]

I know it's boring and repetitive to talk about how grossly evil Trump is, but the fact remains: Trump is grossly evil, in a way that's pretty much unprecedented in this country.

[Ilya Levental @LeventalLab]

@BranniganLab its true!

[ned! @nedsore]

the shower is the alternate dimension where I realize I'm low on shampoo but as soon as I step through the curtain I'm transported back to this dimension where all my memories are wiped like in severance and I won’t remember i’m out of shampoo until im back in the shower

[Denis Wirtz @deniswirtz]

Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign.

(1) $48.7 billion for NIH
(2) Full IDC recovery
(3) No more multi-year funding
(4) No NIH reorganization, maintaining the current IC structure.

[Biophysical Journal @BiophysJ]

#OPENACCESS: Asymmetry and heterogeneity in the plasma membrane. Teppei Yamada and Wataru Shinoda. https://t.co/91pfpJSMMd

[Uri Alon @UriAlonWeizmann]

Biopsies provide just a single snapshot of the underlying tissue. In our recent work published in @Nature, we made progress in estimating tissue-level dynamics from a biopsy using spatial proteomics.

https://t.co/fLQgUqvNNC