@BrianKingNeo@neosatyan@natetexsun@CardioNeo@vkakkilaya The ÉCLAT infants would likely have a slightly different lung pathology at this stage. Very thought provoking!
Personally I do wonder if there is a mechanical element to higher CPAP levels assisting in narrowing/ closing PDAs but that is just me musing 💭 🤷♀️ 🫁
@BrianKingNeo@neosatyan@natetexsun@CardioNeo@vkakkilaya Oooooo interesting questions! Brian is correct- ÉCLAT population was a little different… keep in mind most of our infants had surfactant at birth (or very soon after), were mechanically ventilated and then extubated on (median) day 3 to CPAP level of either 8 or 10cmH2O.
Extubation failure occurs in over half of extremely preterm infants extubated to standard CPAP levels but drops to about one-third when using higher CPAP levels of 10 cm H2O. This simple adjustment could substantially reduce reintubation and improve respiratory outcomes in these vulnerable babies. Learn more about this important neonatal respiratory care research by listening to the full episode here: https://t.co/Qvs6Y7CdxI.
Wow! What a way to start the new year after a break from social media!
The ÈCLAT trial took a village! The work supporting respiratory support for preterm infants isn’t over yet! We only scratched the surface 🫁 🌟
Congrats to the ECLAT trial - voted the 2023 Impact Article of the Year!
How did this trial impact your practice?
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#neotwitter:
For a 22 week 400g infant intubated in the delivery room, with minimal oxygen requirement, normal blood gases, spontaneous respiratory effort and no other major contraindications, I would attempt extubation:
@BrianKingNeo@LindseyKnake@guisantanna In ÉCLAT we had some extubation success in a couple of infants 23&24 weeks in first week of life… whilst growth is important, I think these infants have to be approached case by case, individual basis and then look at optimising their post extubation support… it is possible….
🎙️ Exciting News! 🌟 The Incubator Podcast is thrilled to announce our new mini-series: "Managing Respiratory Distress: Flow and Pressure." Where we discuss the new evidence in the management of respiratory distress in critically ill newborns 🫁
A huge shoutout to @fphcare for their generous sponsorship, making this series possible! 👏
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