🚨 My first first-author PhD paper is out in @AJHGNews!
We developed a single-cell TWAS pipeline that pinpoints cell-specific genetic drivers of cardiovascular disease—more precise than bulk-based methods 🧬
🔗 https://t.co/VemD2J7l0S
#Genomics#PhDlife#scRNAseq#TWAS
Presented this work at CHARGE (Maryland) and #ESHG2025 🎤✨
So grateful to my advisor @MariosGeorgakis and co-authors. Keep an eye out for future updates as this work evolves 👀
Two presentations from our lab next week❗
👉@lanyue_Zhang96 (Young Investigator Fellowship) on proteomic signatures of atherosclerosis at @EASCongress in Glascow
👉@AnushreeRay4 (Travel Award) on single-cell drivers of atherosclerosis at @chargetiger meeting in Maryland
🚨 Excited to share - now available on medRxiv my first first-author preprint: "Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease"
https://t.co/ROdu6R3CIP
This framework bridges cutting-edge single-cell transcriptomics with translational insights into CVDs and beyond, paving way for precision treatments like RNA-based therapies
Is IL-6 signaling always bad❓
Our recent study with @PMyserlis@AnushreeRay4@CDAndersonMD tests if 🧬genetic proxies for IL-6 signaling downregulation are linked to
1⃣Alzheimer's disease
2⃣lobar intracerebral hemorrhage (cerebral amyloid angiopathy)🧠
https://t.co/XmCbP8ppbw
🚨Postdoc Opening🚨
We're seeking a skilled scientist to lead research in multiomics❗️
Join our excellent interdisciplinary team👇in our efforts to tackle pressing challenges in cardiovascular disease
Lab: https://t.co/lWl8pe5AbM
Position: https://t.co/gumHahkZ58
Please RT!
Is the effect of HDL cholesterol on coronary heart disease of interest? Are the assumptions of Mendelian randomization in this situation "vaguely reasonable"? And except for RCTs and MR which causal inference approach got close to the right answer? Interested in views on these
Pleased to see our (@dpsg108 ) new review online: 'Mendelian randomization as a tool to inform drug development using human genetics'. A primer on how to use MR for drug dev, with applicable examples from studies of IL-6. Hope it's helpful!
https://t.co/WPK0XEJTLV
@PostNL Exhausted from trying to find where my parcels are for the last 3 months!!! Talked to customer service several times, filled like a million forms. Giving up on my precious memories now😢
@PostNL But now being told it is at a service point. I filled forms to change address of delivery/authorise a friend in NL to receive the parcel. But now being told a third person cannot receive my parcel.