Archit Ghosh

Postdoc @MDAndersonNews | Chicago to Houston | Entranced by all things 3D Genomics, Cell State Transition & Epigenetics

[Archit Ghosh @ArchitGhosh1]

Yesterday, I successfully defended my PhD thesis!!! I still can't believe it. Finally. Thank you to my committee members @raikunal (chair), Mark Bedford, @Jeffrey_T_Chang , @KylePEagen & @nicholas_navin. And thank you to all those who attended and cheered me on. <3 @UTGSBSGnE

[Chicago Bulls @chicagobulls]

We are devastated by the passing of 3x NBA Champion and beloved broadcaster Stacey King.

[Archit Ghosh @ArchitGhosh1]

Context-dependent synthetic lethality — an emerging precision therapeutic approach. @NatureRevCancer
https://t.co/NC7tw0DiFE

[Archit Ghosh @ArchitGhosh1]

Plasma signals of lung tumor promotion for molecular cancer prevention. @CellPressNews, @TheCrick, @WEHI_research, @uclh, @CRUK_MI
https://t.co/unAVlfIh35

[Eric Topol @EricTopol]

Expanding the CRISPR genome editing toolkit:
A flip from RNA-guided DNA targeting to DNA-guided RNA targeting @NatureBiotech
https://t.co/GxKVthgbxh
https://t.co/UIifna0nsF
https://t.co/2ZB1eJzpCe

[Nature Biotechnology @NatureBiotech]

Widespread DNA off-targeting confounds RNA chromatin occupancy studies https://t.co/1ajHMk8RQG

[Archit Ghosh @ArchitGhosh1]

Context-dependent synthetic lethality — an emerging precision therapeutic approach. @NatureRevCancer
https://t.co/NC7tw0DiFE
https://t.co/CQI06OPGF7

[Archit Ghosh @ArchitGhosh1]

Engineering challenges and translational opportunities in emerging gene delivery platforms. @natBME
https://t.co/4DuMZ1nouX

[Archit Ghosh @ArchitGhosh1]

Alterations of chromatin state at transposable elements rewire stemness in acute myeloid leukemia. #ResearchBriefing @NatureGenet
https://t.co/3ZUDuQOyYO

[Archit Ghosh @ArchitGhosh1]

A high-MAPK, low-WNT cell state drives metastatic dissemination in colorectal cancer. https://t.co/e0bQM6TQ1t

[Archit Ghosh @ArchitGhosh1]

Whole-genome doubling drives immune evasion by silencing antigen presentation. https://t.co/SNtmJDddXX

[Mathieu Lupien @MatLupien]

Excited to share our @natgenet.nature.com study showing that epigenetically rewired transposable elements control AML leukemia stem cell properties and patient outcome.

Grateful to the team & collaborators. https://t.co/3XO9vlbLUT

[Scientific American @sciam]

Scientist and medical technology entrepreneur J. Craig Venter published the first bacterial genome ever decoded in 1995. The result heralded a new age of discovery for genetics
https://t.co/dA7HEOCDg2

[Molecular Cell @MolecularCell]

Online Now: PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes https://t.co/6VCSXYrsOF

[Molecular Cell @MolecularCell]

Online Now: Cohesin cofactor dosage sets the rate of loop extrusion, rendering genome folding tunable yet vulnerable to genetic disruption https://t.co/uBOob7XZPs

[Molecular Cell @MolecularCell]

Online Now: Mutual antagonism between PRC1 condensates and SWI/SNF in chromatin regulation https://t.co/lQRi5kmQQ8

[Nature Biotechnology @NatureBiotech]

Comprehensive profiling of clinically approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing https://t.co/29eHF5iTzP

[Archit Ghosh @ArchitGhosh1]

Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration | Science https://t.co/0k9mCMBMev

[Archit Ghosh @ArchitGhosh1]

Synthetic super-enhancers enable precision viral immunotherapy.
https://t.co/54vYVi7wzy

[Archit Ghosh @ArchitGhosh1]

https://t.co/A2ZjQTr4HV

[Archit Ghosh @ArchitGhosh1]

Transposable element–gene chimera cartography, origination and role in enhancing transcriptome plasticity. https://t.co/4dxE6xzrIp