Ariella Coler-Reilly🏳️‍🌈

⚕️MD PhD Candidate @WUSTLmed 🏳️‍🌈👩🏼‍🔬Aging | @UCBerkeley 🐻 | New favorite thing is doing art on @Twitch #SciComm #SciArt 🎨 | 🇺🇸🇯🇵

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

It's amazing that you were able to live-tweet all this! Thank you so much @rheum_cat , you're the best!! 🐱❤️

[Rheum Cat @rheum_cat]

Western themed graphics talk from @AriellaStudies #ACR23

🤠

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

That's me! I'm Researchers! 😁
Very nice to see this excitement. 🎉

Original paper here: https://t.co/V3LmI3wUlU

[Dr Singularity @Dr_Singularity]

Big anti aging news

Scientists Identify Core "Aging Genes" Shared Across Species. Silencing Them Extends Lifespan

Researchers publishing in Aging Cell have pinpointed a set of core genes that drive aging across multiple species, from humans to worms.

By analyzing 25 large gene expression datasets and testing the results in C. elegans, they found 6 key genes whose suppression extended lifespan by up to 15%.

These genes regulate immune activity, tissue maintenance, and DNA stability, and many are already linked to age related diseases like Alzheimer’s and macular degeneration.

The findings reveal universal aging mechanisms and new targets for anti aging therapies.

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@Dr_Singularity @schellerlab @CiviRobyAc @zacharypincus @WashU_MRC @WUSTLmed @Aging_Cell The tech specs of the method:
🧫A single dose/lawn of RNAi-laden bacteria on IPTG plates.

My awkward yet I think pretty effective analogy:
🍄I micro-dosed them on gene interference.

2/2

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@Dr_Singularity @schellerlab @CiviRobyAc @zacharypincus @WashU_MRC @WUSTLmed @Aging_Cell One frequent comment here is about the strength of the lifespan extension (~15% or less) being relatively low. I agree! I did not maximize lifespan. I actually used quite a weak method of gene interference... just enough to confidently detect the signal I was looking for. 1/2

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@AgingBiology This is my paper 🤗 Thank you for sharing! 🥳

[Jason Colasanti, PhD @JasonColasanti]

🎉 Congrats to @AriellaStudies on her new publication based on her thesis work! 👏🍾

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@briantylercohen @hulu +1 @hulu @Disney

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

I guess technically "content availability"? 😅

Glad I procrastinated canceling Hulu so I could do it today specifically ✨

#TeamNetflix

[a 🗡️🍉 @ama_a93]

dont open an etsy shop 😃 (1/4)

[Lacey Feigl (moved to @Bluesky @LaceyFeigl) @LaceyFeigl]

We had so much fun recording this week's @RheumMadness podcast to talk about our #RheumMadness scouting report on "Steroid Dose in Lupus Nephritis"! You can find our scouting report here: https://t.co/QWt4zEwJ6r... and the first half of the "Full Court Care Champions" (1/2)

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@NaomiDirckx @WashU_BMD @CiviRobyAc @schellerlab elegan(s)(t) 😂❤️🐛

[CORE IM @COREIMpodcast]

1/ 🚨 NEW #AtTheBedside: Moral Distress Part 2: Strategies & Solutions

The FIRST and most important step in addressing moral distress: 

❤️‍🩹Naming it

We must identify what we’re actually feeling

🖥️: https://t.co/tgbPZA8ZjQ

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@rheum_cat @kristenyoung I honestly just don't know what else to do besides keep going to work. It can't be broken... I feel like I would be in way more pain... so I don't need an x-ray.... so.... I guess I just keep icing and RICEing when I'm home? I have my wonderful home RICE aid a.k.a. fiancé😂❤️

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@rheum_cat @kristenyoung That sounds like a wild story!

[Scheller Lab @schellerlab]

🚨After 8y and many dead ends- we are excited to clarify how "stable" adipocyte lipolysis is potently activated independent of catecholaminergic signals while being restrained by glucose and insulin. RT and feedback welcome as we work from preprint to pub! https://t.co/3wO3lUDDfw

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@DrPujaMehta1 As tough as I like to think I am, I'm pretty sure I'd have been in too much pain to limp around on a single tylenol if it were broken... but feel free to weigh in!👇

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

@rheum_cat @kristenyoung No i went to work! Sorry for the delay, finishing the story now.

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

... I successfully reached the nurse's station on our floor and asked for help getting some bandages and ice packs, and the nurses very kindly obliged.

While the team was occupied with hand-off, I quietly washed up, bandaged my hands, and iced my ankle, which looked okay...

5/x

[Ariella Coler-Reilly🏳️‍🌈 @AriellaStudies]

... to be fair, I figured work is literally in a hospital, so it's not a bad choice of location if I develop a need for medical attention.

Fortunately, the asphalt dirt blended perfectly into my dark gray heather scrubs, so I didn't look alarming...

4x