Allen Esterly

PhD | Infectious Disease 🦠 | Immunology

[Eric Topol @EricTopol]

The relationship of physical activity and life expectancy
https://t.co/6pdJTOWGPi
Summary points from the paper:
—Americans over the age of 40 could live an
extra 5.3 years if all were as active as the top
25% of the population.
— For the least active 25% of Americans, an extra
hour’s walk could add 6.3 hours of additional
life expectancy.

[Heidi Zapata, MD PhD @HeidiZapata77]

Celebrating the election of Erol Fikrig into the National Academy of Medicine! @YaleIMed @YaleIDFellows @YaleMedicine

[internet hall of fame @InternetH0F]

Galaxy in a drop of water

[Dylan Burnette @MAG2ART]

A cell videoed through a microscope. DNA in the nucleus (green) and the powerhouses/overlords of the cell, mitochondria (purple), are shown. #CellBiology

[Curiosity @CuriosityonX]

A recent image of Jupiter captured by Juno spacecraft.

[Rafael Kroon Campos @RafaelKCampos]

Are you interested in arbovirus-host interactions? My lab @CornellPathogen is searching for a Postdoctoral Associate to study mechanisms of infection and transmission focusing on alphaviruses and flaviviruses . Apply now! 🧪🔬🦟  https://t.co/QZsF7Wn5Mw

[Nature Rev Immunol @NatRevImmunol]

Location matters: mapping antigen receptors within tissues https://t.co/NcE5ccq1yX

[Hao Yin @HaoYin20]

Systematic comparison of 11 sequencing-based #SpatialTranscriptomics methods
A must-read for spatial omics researchers🤠

Visium
DynaSpatial
HDST
BMKMANU S1000
Slide-seq V2
Curio Seeker
Slide-tag
Stereo-seq
PIXEL-seq
Salus
DBiT-seq
Guess which behaves best for🧠microvasculature?😁

A standard benchmarking pipeline
▶️Molecule-capture efficiency (per unit area)
▶️Molecule lateral diffusion
▶️Clustering/Cell annotation (Seurat still outperforms https://t.co/bOzbm4y9xe or PRECAST😯)
▶️Marker gene detection
▶️Cell-to-cell communication (no consistent results found)

💰Fig 4f Affordability

Xiaodong Liu & Luyi Tian labs @naturemethods 2024 @ethanxdliu @Luyi_T
https://t.co/qe7iiArFcW

+ cadasSTre, a website for raw/processed data #OpenScience
https://t.co/rJnFr15DAi

[Thangamani Lab, SUNY Upstate ☣️🧬🦟🐁🦠 @Thangamani_Lab]

Looking forward to share/ discuss some of our recent findings.

[Nature Reviews Molecular Cell Biology @NatRevMCB]

Now Online SenNet recommendations for detecting senescent cells in different tissues https://t.co/JAw6hd7z36

[Dr Paddy Barrett @Paddy_Barrett]

Muscle Mass & Muscle Strength

Are major determinants of how long you will live and the quality of your life as you age.

Here's why.

🧵👇

/1

[Thangamani Lab, SUNY Upstate ☣️🧬🦟🐁🦠 @Thangamani_Lab]

Excited to share our preprint article: #Powassan

Comparative pathogenesis of two lineages of Powassan virus reveals differing routes of neuroinvasion leading to distinct clinical outcome, neuropathology and inflammation https://t.co/a5UL2xT0zt

[Allen Esterly @AtEsterly]

@gvshrivastava Congratulations!

[Allen Esterly @AtEsterly]

Great to meet the man behind the mic! Thanks @PWB_Global for having @profvrr at @ASTMH 2022 #TropMed2022 @ACAV_ASTMH

[Allen Esterly @AtEsterly]

@AliotaLab @ASTMH @ACAV_ASTMH Interesting work!

[Nature Rev Immunol @NatRevImmunol]

NEW Review: The roles of extracellular vesicles in the immune system
https://t.co/z4VAMCxBcA
by @EditBuzas @semmelweishu
including roles of #EVs in innate and adaptive immunity, and potential use for diagnosis and therapy
#extracellularvesicles #exosomes

[Allen Esterly @AtEsterly]

Official received my PhD today. A huge thank you to the scientists that have trained me to be able to achieve this milestone. Looking forward to what the future holds @Thangamani_Lab @ShirleyLuckhart @AlamedaMosquito @nazzy_bug

[Nature Reviews Molecular Cell Biology @NatRevMCB]

Now Online Challenges and directions in studying cell–cell communication by extracellular vesicles https://t.co/5l8K0x4FfP

[medRxiv @medrxivpreprint]

First detection of Powassan Virus lineage I in field-collected Dermacentor variabilis from New York, USA https://t.co/Ohe0sguaCk #medRxiv