Danmaigoro

Just a based chill guy

[Nerdx @Nihon_nerd]

Most men don’t realize: amino acids like L-Arginine aren’t just gym fuel, they’re backed by meta-analysis as potentially improving erectile function by boosting nitric oxide + blood flow. 🧬🍆

That’s why @d1ckdao isn’t just memes. It’s DeSci in action.
...and with @BioProtocol, research → community → protocol = realigned incentives for men’s health.

[Nerdx @Nihon_nerd]

With the market for memory boosters, focus aids, brain health supplements, and general cognitive enhancers estimated to reach more than $20 Billion over the next decade, the trend is clear. @NootropicsDAO_, also known as "smart drugs", are here to stay. @NootropicsDAO_ is building the world's most effective global infrastructure for decentralized research, discovery, and commercialization of powerful solutions for human cognitive enhancement. By creating an open-science ecosystem that aligns professional researchers, citizen-scientists, and biohackers to govern a community-directed research and development pipeline with hyper-efficient feedback loops, Nootropics DAO is operating to become the dominant force in the rapidly growing nootropics industry. This article considers new data on the key molecular mechanisms which may underlie the neuroprotective properties of multicomponent organ-specific medicinal formulations consisting of peptide hydrolysates extracted from animal brains.

Such formulations, including cortexin, are currently quite widely used in the treatment of cerebral pathologies. The potential molecular mechanisms of the neuroprotective effects of cortexin are shown to be diverse and to influence key processes underlying neuroplasticity: signal transduction, energy metabolism, proteolytic modification of proteins, brain cell structures, and neuroinflammation processes. The pleiotropic nature of the mechanisms of action of cortexin results from the composition of the formulation, which contains a multitude of different neuropeptides. The tissue specificity of the molecular mechanisms identified here to a significant extent determines the efficacy of the agent in cerebral pathologies.

🚀 The $20B+ nootropics market is just the beginning. Cognitive enhancement is no longer sci-fi, it’s science.

🌐 @NootropicsDAO_ is building the world’s first decentralized bio-protocol for brain health + performance:

Open-science ecosystem

Citizen + pro researcher collaboration

Hyper-efficient feedback loops

Community-governed R&D pipeline

🧠 Why now? Cutting-edge research shows multicomponent peptide-based nootropics (like cortexin) can modulate neuroplasticity, energy metabolism, signal transduction, & neuroinflammation. These pleiotropic effects = massive therapeutic + cognitive potential.

@NootropicsDAO_ is the infrastructure layer to accelerate discovery, testing & commercialization of these next-gen compounds, aligning incentives between scientists, biohackers, & patients.

💡 This isn’t just supplements, it’s a @BioProtocol for human intelligence.

#DeSci #Nootropics #BioProtocol #NootropicsDAO

[Nerdx @Nihon_nerd]

This user is going to be eligible for @idOS_network rewards

I just can’t prove it yet

Who’s with me?

[Nerdx @Nihon_nerd]

Gm if you Gm

Preach @AnichessGame

[Danmaigoro @BasedChilGuyCTO]

@Nihon_nerd @AnichessGame $CHECK nerd

[Nerdx @Nihon_nerd]

I’ve been following the buzz around @AnichessGame, and it’s hard not to notice the momentum building. With the launch of $CHECK expected this October, a lot of eyes are turning in their direction. Personally, I’m interested, but I don’t believe in putting all my resources into a single play, balance matters.

That said, Anichess really does stand out. They’ve managed to take the classic game of chess and add an innovative twist that makes it feel both familiar and completely new. It’s rare to see a project tap into such a universal concept and still keep it fresh.

I’ve also noticed names like @fastlife, who has been on point with calls recently, and @ripchillpill, who’s been exploring this space too. Seeing respected voices engage with it adds a layer of confidence.

At the end of the day, I see this as one of those projects where being early could make the difference, but I’m keeping perspective and treating it as part of a broader strategy. The grind is real, and if there’s a leaderboard worth climbing, this could be one to watch closely.

Happy Weekend CT🦜

$CHECK

[Nerdx @Nihon_nerd]

ANICHESS 😲

It’s only been a few days since I started diving into Anichess, and the more I explore, the more convinced I am that this project is something special. The vision, the gameplay mechanics, and the community direction all feel fresh compared to most things we see in the space.

Instead of being just another “engagement farm,” @AnichessGame is shaping up to be much more:
🎮 A strategy-driven game with depth.
🌐 A growing, passionate community.
🔥 A movement forming around a strong narrative.

Yes, the market is struggling right now. Charts are red, sentiment is weak, and a lot of people are losing conviction. But here’s the difference: when you actually believe in the fundamentals of what’s being built, short-term volatility matters a lot less.

That’s why I keep coming back to Anichess and $CHESS. Every day I spend learning more about the project, I see new layers of potential. From the gameplay innovation to the way they’re merging chess strategy with Web3 mechanics, it’s clear this isn’t a fleeting trend, it’s the early stages of something much bigger.

The most exciting part? This is just the beginning. We’re still in the early days, and being early in narratives like this is often where the strongest opportunities are found.

Anichess isn’t just “cooking”, it’s laying the groundwork for a lasting ecosystem. And I’m here for the long run.

[Danmaigoro @BasedChilGuyCTO]

@Nihon_nerd GM buddy

[Nerdx @Nihon_nerd]

GM CT

Just another day to try again 📈

[Nerdx @Nihon_nerd]

TRIAXIS, @D1ckDAO’s advocacy, and the Vitamin D3 transdermal delivery research

🧵
Speaking of TRIAXIS;

1/
Today, most #TRT relies on injections, painful, invasive & often linked to poor compliance + side effects.
TRIAXIS explores safer, smarter alternatives: oral, transdermal & hybrid systems.

2/
Just like testosterone, Vitamin D3 suffers from bioavailability challenges.
Oral forms depend on fat absorption, making them unreliable for people with:

celiac disease

chronic pancreatitis

biliary obstruction

cystic fibrosis

Transdermal delivery could change that.

3/
📑 Recent research tested penetration enhancers for Vitamin D3 transdermal delivery:

oleic acid

dodecylamine

ethanol

isopropyl myristate

octyldodecanol

🔬 The game changer? Dodecylamine + ethanol pretreatment → delivered 760 ng/cm² through porcine skin!

4/
Why does this matter?

Vitamin D3 isn’t just about bones, low levels are linked with:

💔 cardiovascular disease

🔥 chronic inflammation

🧬 cancer risk

🦠 immune dysfunction

Optimizing delivery = optimizing health outcomes.

5/
This parallels TRIAXIS goals:
✅ Overcome absorption variability
✅ Improve patient adherence
✅ Reduce side effects
✅ Deliver precise, sustainable hormonal support

A bio-protocol for restoration science, from testosterone to vitamin D3.

6/
🌐 @D1ckDAO is raising awareness & funding innovation in this space, bridging men’s health, ED recovery, and hormone optimization through real science.

Future steps:

Expand transdermal protocols for TRT & Vitamin D3

Explore nanocarriers / lipid-based enhancers

Develop patient-friendly bio-hybrids

7/
🔑 Keywords for the future of delivery science:
#dodecylamine | #ethanol | #penetrationenhancer | #transdermal | #VitaminD3 | #TRT

💡 Restoring health isn’t just about replacement, it’s about precision delivery.

TRIAXIS + @D1ckDAO = leading that revolution. (@BioProtocol)

Got this with the help of articles from AAPS PharmSciTech which are provided here, courtesy of American Association of Pharmaceutical Scientists

This is the end of the thread 🧵

[Danmaigoro @BasedChilGuyCTO]

@Nihon_nerd @D1ckDAO @BioProtocol @microbiomedao It's all good timing

[Danmaigoro @BasedChilGuyCTO]

@Nihon_nerd Real soon

[Nerdx @Nihon_nerd]

Hopefully I get to say mama I buy you house😭🤲

[Danmaigoro @BasedChilGuyCTO]

@Nihon_nerd @BioProtocol @D1ckDAO Looking good in here

[Nerdx @Nihon_nerd]

Over 300M men worldwide suffer from ED.
1 in 3 experience premature ejaculation.
Testosterone levels have dropped >20% since the 2000s.

and yet…

° Men’s sexual health market projected to surpass \$6B by 2030
° NIH spends <1% of its funding on male sexual health
° There’s no Office for Men’s Health, no dedicated focus, no urgency

Men are struggling in silence while quick-fix pills dominate.

This isn’t just about performance, it’s about identity, confidence, and health.

In the coming days I’ll be yapping on @D1ckDAO and @BioProtocol, a push for real science, real solutions, and a future men can stand proud in.

[Nerdx @Nihon_nerd]

Goodnight guys

Enough on farcaster and base app today

[Nerdx @Nihon_nerd]

Account wey I dey struggle dey build una dey call am small account asif the effort I'm putting in it is small

Gats be ment

[Danmaigoro @BasedChilGuyCTO]

@Nihon_nerd @SalimoAnne Getting connected

[Nerdx @Nihon_nerd]

@SalimoAnne Gm verified let's connect and grow together actively doing same

[Nerdx @Nihon_nerd]

@sayamame_012 馬の健康が最も重要です。

gn