I'm experimenting with 5-MeO-DMT because it may be most underrated longevity molecule no one is talking about.
+ Accelerated neurogenesis: a single dose more than doubled brain cell proliferation and neuronal regeneration in the hippocampus within 12 hours, alongside measurable increases in synaptic density and firing frequency in rodent models.
+ Proteomic reorganization: in human cerebral organoids, 5-MeO-DMT triggers rapid proteomic shifts favoring cellular reorganization and synapse formation. Early evidence of structural brain renewal at the molecular level.
+ Default Mode Network reset: The DMN calcifies with age locking us into rigid, repetitive patterns of thought. 5-MeO-DMT disrupts these patterns, restoring bottom up connectivity between sensory and creative brain regions. A forced return to neurological flexibility and youthfulness.
+ Systemic anti-inflammation: suppresses pro-inflammatory cytokines (IL-1ฮฒ, IL-6, TNF-alpha) while upregulating IL-10, the anti-inflammatory signal. Mediated through the Sigma-1 receptor, suggesting a mechanism distinct from other psychedelics.
I'm experimenting with 5-MeO-DMT because it may be most underrated longevity molecule no one is talking about.
+ Accelerated neurogenesis: a single dose more than doubled brain cell proliferation and neuronal regeneration in the hippocampus within 12 hours, alongside measurable increases in synaptic density and firing frequency in rodent models.
+ Proteomic reorganization: in human cerebral organoids, 5-MeO-DMT triggers rapid proteomic shifts favoring cellular reorganization and synapse formation. Early evidence of structural brain renewal at the molecular level.
+ Default Mode Network reset: The DMN calcifies with age locking us into rigid, repetitive patterns of thought. 5-MeO-DMT disrupts these patterns, restoring bottom up connectivity between sensory and creative brain regions. A forced return to neurological flexibility and youthfulness.
+ Systemic anti-inflammation: suppresses pro-inflammatory cytokines (IL-1ฮฒ, IL-6, TNF-alpha) while upregulating IL-10, the anti-inflammatory signal. Mediated through the Sigma-1 receptor, suggesting a mechanism distinct from other psychedelics.
Thereโs something off here. Claiming Khomeini is dead. How did they find him so quickly? Why wasnโt he in a bomb shelter? Saddam and Osama took ages to be found. Iran/IRGC were expecting this + fully battle ready, this doesnโt seem right.
Meshuggah are masters of music theory. Polymeters, ghost notes and time signatures so GOATED and technical, no musician across any genre comes close.
Meshuggah is even studied in classical music theory classes.
@mayukh_panja Iโd read the alchemist by Paulo Cohelo as a kid coz it was hyped up so much. Straight up boring and just dumb. Shit didnโt even make sense. Looking back it was a PR storm by the publishing house. People who find it โdeepโ dunno what deep is.
@SStricklandMMA L take. After 30 you barely have 30 more years to go. Stop taking existence so seriously. Itโs a joke and inherently meaningless. Just enjoy the ride and stop giving so many fucks.