Our new paper is now online: https://t.co/2JK4LocF1X. We describe how kinetochore proteins, essential for chromosome segregation, form linear elements in the cytoplasm and have a previously unrecognized role in vesicle transport! Check out our movies!
Basal bodies (BBs) are what eventually become motile cilia. So, if they don't get positioned correctly on the apical surface, the whole tissue level function can go wrong → ciliopathies. We know actin is involved… but how does it actually control this process? 🤔 (3/17)
Also in Issue 9:
- Research Highlights on plasmalogens, tricalbins, protein secretion and cell division
- Interview with Noboru Mizushima
- A century of cell death research
- The Balbiani body at a glance
https://t.co/fvSjO5tssu
My lab is accepting applications for a fully funded postdoctoral fellow position, beginning in 2027. Applicants must clearly articulate specific interests in our lab's research.
Yang et al show that #Celegans CKS-1 is required, w/ CDK-1, for #anaphase B during oocyte #meiosis I; promotes anaphase onset thru. securin & cyclin B1 destruction in meiosis I & II, respectively; & acts positively w/ both securin & cyclin B3 in meiosis II https://t.co/19jo6e9xFw
Spotlight: Moghareh, Bojorquez, and Lara-Gonzalez @ucirvine highlight work from Yang et al. (https://t.co/OQAGnZ1vRW) showing that CKS-1 plays key roles in both #anaphase B during #oocyte#meiosis I and the #metaphase II–to–anaphase II transition. https://t.co/2rFIFec9hE
How is timely and accurate sister chromatid separation achieved?
A process that is happening around 30-50 billion times per minute!!! in the human body needs tight regulation (to avoid cancer development...).
paper:
https://t.co/X0uF42A06a
comment:
https://t.co/8inOxfGlve
Been doing a lot of time lapses of iPSC-derived cardiac muscle cells lately! Here's one of my favorites. This cell is expressing fluorescent alpha-actinin-2 and the colors represent depth. Movie length = 24h with frames taken every 20m. #microscopymonday#cellbiology@MAG2ART
John Philip Trinkaus, a student in the 1939 Embryology course, left us with his drawings that show 'presumptive regions' in Trout, Fundulus, Dog fish, and Urodele; development of circulatory system of Teleost; and a squid spermatophore.
https://t.co/i4FGs3HWMy