Our new paper is now online: https://t.co/2JK4LocF1X. We describe how kinetochore proteins, essential for chromosome segregation, form linear elements in the cytoplasm and have a previously unrecognized role in vesicle transport! Check out our movies!
New JCS snapshot - Outer kinetochore proteins form linear elements to regulate vesicle transport
Shane Kowaleski presents the key findings from their recent JCS paper with Joshua Bembenek and team.
https://t.co/JCr118QJ36
Basal bodies (BBs) are what eventually become motile cilia. So, if they don't get positioned correctly on the apical surface, the whole tissue level function can go wrong → ciliopathies. We know actin is involved… but how does it actually control this process? 🤔 (3/17)
Also in Issue 9:
- Research Highlights on plasmalogens, tricalbins, protein secretion and cell division
- Interview with Noboru Mizushima
- A century of cell death research
- The Balbiani body at a glance
https://t.co/fvSjO5tssu
My lab is accepting applications for a fully funded postdoctoral fellow position, beginning in 2027. Applicants must clearly articulate specific interests in our lab's research.
Yang et al show that #Celegans CKS-1 is required, w/ CDK-1, for #anaphase B during oocyte #meiosis I; promotes anaphase onset thru. securin & cyclin B1 destruction in meiosis I & II, respectively; & acts positively w/ both securin & cyclin B3 in meiosis II https://t.co/19jo6e9xFw
Spotlight: Moghareh, Bojorquez, and Lara-Gonzalez @ucirvine highlight work from Yang et al. (https://t.co/OQAGnZ1vRW) showing that CKS-1 plays key roles in both #anaphase B during #oocyte#meiosis I and the #metaphase II–to–anaphase II transition. https://t.co/2rFIFec9hE
How is timely and accurate sister chromatid separation achieved?
A process that is happening around 30-50 billion times per minute!!! in the human body needs tight regulation (to avoid cancer development...).
paper:
https://t.co/X0uF42A06a
comment:
https://t.co/8inOxfGlve
Been doing a lot of time lapses of iPSC-derived cardiac muscle cells lately! Here's one of my favorites. This cell is expressing fluorescent alpha-actinin-2 and the colors represent depth. Movie length = 24h with frames taken every 20m. #microscopymonday#cellbiology@MAG2ART