Benjamin Grodner

BME PhD Student in De Vlaminck Lab at Cornell University

[Benjamin Grodner @BenjaminGrodner]

Our paper! 🪩

"Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes"

Full text link:
https://t.co/ZsV0WOH7ci

[Benjamin Grodner @BenjaminGrodner]

@ShaunTCross @IwijnDeVlaminck Thanks Shaun!!

[Benjamin Grodner @BenjaminGrodner]

Check out the manuscript for all the lovely details and discussion!
https://t.co/ZsV0WOH7ci

[Benjamin Grodner @BenjaminGrodner]

Our paper! 🪩

"Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes"

Full text link:
https://t.co/ZsV0WOH7ci

[Benjamin Grodner @BenjaminGrodner]

This method can help advance the study of microbial ecology, serving as a complement to metagenomic sequencing by revealing the spatial interplay between bacteria, plasmids, and phage.

[Dr. Heather Armstrong @DrHArmstrong]

📢 Short talks:

Dr Ben Grodner @Cornell
✅HiPR-FISH (PMID: 33268897) maps genera spatial heterogeneity (#biofilms)
✅MGE-FISH mapping mobile genes
✅overlap tools to determine interactions and spatial ecology
https://t.co/miGqIbhxPu
#HavingIMPACTT2023 @IMPACTT_Canada

[Joe J. Harrison @JoeJHarrison1]

Elegant technique from @BenjaminGrodner using molecular barcoding to visualize mobile DNA transfer - many applications to microbiome studies, bacterial genetics, and basic biofilm microbiology. Also - beautiful images. #HavingIMPACTT2023 @IMPACTT_Canada
https://t.co/rGOoarECnQ

[Benjamin Grodner @BenjaminGrodner]

First, the methods could be employed to investigate the processes that govern the emergence of antibiotic resistance.

Second, MGE mapping can help address the challenge of determining bacteriophage host taxa, which is crucial in phage therapy.

[Benjamin Grodner @BenjaminGrodner]

I’m very pleased to share our new preprint where we simultaneously map MGEs and bacterial taxa in complex microbiomes, revealing their spatial structures.

[Iwijn De Vlaminck @IwijnDeVlaminck]

Spatial Mapping of Mobile Genetic Elements and their Cognate Hosts in Complex Microbiomes https://t.co/xlUpP9q0kF

[Benjamin Grodner @BenjaminGrodner]

We suggest that MGE mapping can serve as a direct complement for metagenomic sequencing of spatially structured microbiomes. We envision two potential application areas.