William Bill Gramer

[William A. Wallace, Ph.D. @WilliamWallace]

Taurine is a sulfur-containing amino acid known for its critical involvement in skeletal muscle, heart and brain function. With high concentrations found in excitable tissues such as muscle, brain, and heart, taurine is essential for maintaining cellular homeostasis. It stabilizes cell membranes, acts as an osmolyte, and plays a central role in modulating intracellular calcium levels and ion channel activity. Taurine also exhibits significant antioxidant and anti-inflammatory properties, enhancing cellular resilience against oxidative stress and inflammation.

Taurine's actions span across multiple tissues and systems, including the central nervous system (CNS), heart, vascular system, immune system, liver, skeletal muscle, and pancreas:

*️⃣CNS: Taurine exhibits inhibitory actions, modulating neurotransmission and supporting neuroprotection.
*️⃣Heart: It enhances inotropy (heart muscle contractility) and provides anti-arrhythmic effects.
*️⃣Vascular System: Taurine contributes to vasorelaxation, blood pressure regulation, and the prevention of atherosclerosis.
*️⃣Immune System: It acts as an immunostimulant, supporting the body's defense mechanisms.
*️⃣Liver: Taurine aids in bile salt synthesis, essential for lipid digestion and absorption.
*️⃣Skeletal Muscle: Taurine enhances muscle performance by regulating calcium homeostasis, membrane excitability, and maintaining muscle phenotype.
*️⃣Pancreas: Taurine promotes insulin secretion, contributing to glucose regulation.
*️⃣Genitourinary System: It may also act as a fertility stimulant, reinforcing its wide-ranging biological importance.

Dosage recommendations, as depicted, range from 1-6 grams per day in clinical studies, with common supplementation protocols using 3-6 grams per day, typically split into two doses.

Taurine's toxicity is remarkably low, with human clinical trials supporting its safety even at high doses. Studies have highlighted taurine’s role in various pathological conditions, including cardiovascular and neurological diseases, making it an amino acid of great interest for its broad therapeutic applications and safety profile

[Camus @newstart_2024]

Roger Federer broke the internet with one statistic that will change how you see every setback in your life.
1,526 singles matches.
Won almost 80% of them.
20 Grand Slams. 103 titles.

Now answer honestly:
What percentage of total points do you think he won across his entire career?
70%? 65%? 60%?

Try … 54%.
He lost literally almost EVERY SECOND POINT he ever played for 24 years.

And still became one of the greatest of all time.

Watch him explain it himself (2:07 of pure life-changing wisdom):
“In tennis, perfection is impossible… When you lose every second point on average, you teach yourself to say:
‘Okay, I double-faulted — it’s only one point.’
‘Okay I got passed at the net — it’s only one point.’
Even a screaming overhead smash that ends up on SportsCenter Top 10… still just one point.

So when you’re playing your point, it has to be the most important thing in the world.
The moment it’s over — it’s behind you.

That mindset frees you to attack the next point, and the next, and the next with absolute intensity and clarity.”

Then he looked at the crowd and said the line that hit a billion people in the soul:
“The real sign of a champion is not that they win every point.
It’s that they lose again and again and again… and have learned how to deal with it.
Negative energy is wasted energy.
Cry it out if you have to. Then force a smile.
Move on. Be relentless. Adapt. Grow.
Work harder — and work smarter.”

Save this post.

The next time you lose a deal, bomb a presentation, get ghosted, miss a deadline, or just have “one of those days” — come back here and read it again.

You’re not falling behind.
You’re just in the 46%.
And the 46% is exactly where every single legend has spent most of their career.

Keep playing the next point.
(full 2:07 clip — sound on)

[William Bill Gramer @BillGramer]

Your contribution to the CCJ article was genius. What I mean by genius is the subtle use of humor blended in and capitalizing on the paranoia of glowing radioactive people in Springfield and Simpsons

… just brilliant.

Then you finished it off with an effortless “EFFORTLESS“ humor for only those who live through the George Bush era ..

You watch Stranger Things too

[Jay Mueller @jmuelle99]

@enCoreEnergy_EU Fire the CEO with no explanation? Not good PR….AT ALL. Investors don’t like uncertainty

[larry barken @larrybarken]

@enCoreEnergy_EU why are you not saying why Paul left. Leads us to believe fraud or something bad without some explanation. U dont put a legal officer in charge of a mining co? where is bill sherriff----is he gone too or doesnt want to b involved

[William Bill Gramer @BillGramer]

Subaru. Forester or outback if you want to haul people.
Crosstrek XV if you want something small and still off-road and very good mileage …

Safety and maintainability ratings off the charts for all Subaru

Get a used one! I know you know the cost benefit. Anything less than 75,000 miles still has 200,000 miles left.

[William Bill Gramer @BillGramer]

@hubermanlab #truth

[William Bill Gramer @BillGramer]

@ZacMannes 👊🏻$ pay attention people. Subscribe : it pays for itself quickly. And you can have fun shorting for a change…

[William Bill Gramer @BillGramer]

@elonmusk merry Christmas Elon. Grateful to have you part of our country’s leadership now.

[Crypto.com @cryptocom]

You’ve seen the film.
Now see how & why we made it.

#FFTB

[Crypto.com @cryptocom]

We’ve crossed a major new milestone.

#CROFam is now 100 million strong 💪

Thank you to all our users who’ve been with us from the start, and those who’ve just joined us. 🙏

Get all the details:
https://t.co/UnzFph4hvw

[William Bill Gramer @BillGramer]

@cryptocom @osmosis @dymension My page returns an error when I try to open it

[William Bill Gramer @BillGramer]

Congratulations. @IowaWBB , using your momentum to build the next national team- for several years. Iowa teams have been a class act for past few years to put the Midwest on the map. Men’s and women’s sports. But women’s sports broke the glass ceiling . Keep going.

[Lucy Olsen @LucyOlsenbball]

New beginnings ✍️ @IowaWBB

#Hawkeyes #letsgo 💛🖤

[William Bill Gramer @BillGramer]

Got it. Yes, I see. I wonder @ what point that chgs in wave (IV) of S&P500… . 😉

[Zachary Mannes @ZacMannes]

@BillGramer Shorting is kinda like playing the Don't Pass line in Craps. It can be fun to do but if you make a big deal about it the other players are going to hate you...

[Zachary Mannes @ZacMannes]

@BillGramer Shorting is kinda like playing the Don't Pass line in Craps. It can be fun to do but if you make a big deal about it the other players are going to hate you...

[William Bill Gramer @BillGramer]

#agree . And @hubermanlab interview of Dr.@PeterAttiaMD along with @PeterAttiaMD interview of Dr. Andrew @hubermanlab made the thesis and key content and protocols of “Outlive” understandable and personally applicable.
“…if you follow its teachings.” - well said. #justdoit 👊🏻

[Bill Ackman @BillAckman]

There are a few times in life when you read a new book and realize that your life will be transformed if you follow its teachings. @PeterAttiaMD’s Outlive is such a book. It can save, or at a minimum massively improve, your life. I can’t imagine a better investment for 28 bucks.

[William Bill Gramer @BillGramer]

#clever

[William Bill Gramer @BillGramer]

Yes. Thanks @lexfridman . At @hubermanlab I’ve found highest-end zero-cost yet peer-reviewed medical and #healthspan data anywhere . He makes break-through protocols from renowned PhD’s in mental and physical health fields understandable and immediately ‘usable’. #Gratitude .

[Lex Fridman @lexfridman]

It's heartbreaking to see a hit-piece written about my friend Andrew Huberman (@hubermanlab). I know him very well, and can definitively say that he is a great human being, scientist, and educator. Hit-piece attacks like this are simply trash click-bait journalism desperately clinging on to relevance.

Andrew should be celebrated. Period. His podcast has helped millions of people (including me) lead healthier lives. Keep going brother! 👊

[Lex Fridman @lexfridman]

It's heartbreaking to see a hit-piece written about my friend Andrew Huberman (@hubermanlab). I know him very well, and can definitively say that he is a great human being, scientist, and educator. Hit-piece attacks like this are simply trash click-bait journalism desperately clinging on to relevance.

Andrew should be celebrated. Period. His podcast has helped millions of people (including me) lead healthier lives. Keep going brother! 👊

[William Bill Gramer @BillGramer]

This is HUGE. IMO , Because she has been so right on some other early technologies... )
Ark Invest Shifts Portfolio, Swaps Coinbase and Robinhood for Newly IPO'd Reddit Shares https://t.co/AGeW8xCfH2 via @bitcoinnews