and i know people are losing their minds on this whole US vs China thing. and yes u can always improve or refine how u compete (i have plenty of ideas on how u can do this that actually achieves the goal of strengthening the US's competitive position). but let's not lose sight of something. the battle is against disease and i've been doing this for two dozen years and we've never had anywhere near enough scientists in the US solving problems, now europe is going the wrong way and it is great we have scientists from china helping to solve problems too. i'm not aware of any chinese copycats that have stolen some US innovators mkt position (i'd love to hear of one), and conversely if something like pd1-vegf pans out and raises standard of care in lung cancer i think americans will want that china discovered molecule, and it'll be good to come via an american company, and btw it catalyzed a number of american followers trying to do better. just a year ago people were worried there would be no gene therapy/editing companies left bc our fda was too tough and now we're worried about too many? it's the golden age of medicine folks, we need more hands on deck, and thats how we can finally beat disease and maybe someday get to talk just about longevity.
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here is link to release announcing new follow-up letter from rare disease coalition focused on restoring regulatory flexibility for rare disease under CBER. note letter and survey is from a coalition of over 140 rare disease leaders, not just rtw.
https://t.co/gIfCiImfZc
As of 12:47PM today, big disparity in intra-day % change of Clinical Stage stocks in $BBC and the Product/Commercial stocks in $BBP, with the latter down -(0.44%) and the former up +4.07% (The $XBI is up +0.80%). Largest movers in $BBC: $WVE $GPCR $KYMR $NRIX $CGEM $ARWR $DYN
Wow - $BBC up 161% since April 8 low. ($XBI no slouch, up 74%). Are we overheated or are we going higher?
$ARWR $REPL $QURE $VRDN $TERN $CELC $CGEM $CGON $DCTH $VERA $ELVN $IMNM $RAPP $PCVX $RVMD
Stifel has published this slide noting $1.2TN of M&A ammo. Compare to $266BN combined mkt cap of $BBC companies. After $MRUS $RNA $MTSR $AKRO, Who's next? $ARVN $CELC $CNTA $COGT $GLUE $IRON $JANX $KYMR $MBX $NUVL $TERN. Who did we miss?
Jefferies put together this amazing chart that really shows how the recent jump in big pharma / biotech m&a activity should continue to reinject capital into the ecosystem. Also props to RTW and Avoro with >$1BN of gains, larger than several multi trillion dollar asset managers.
@financebully true but with $BBC up 127% since the april bottom, their losses probably pale in comparison to the 5x and 10x gainers in their portfolios. rising markets cure all.
Remarkably, since the April 8, 2025 low in biotech, $BBC is up a whopping 127% (!!!). $XBI is no slouch, +60%. And lower risk $BBP +46%. Notably, the recent biotech M&A binge has been focused on clinical stage companies (those in $BBC), versus being more heavily weighted to $BBP
also notable is how the advisory banking fees were spread around, which is great for the ecosystem. need to check: Metsera was baml, merus jefferies, akero ms, avadel jpm, avidity gs