Actually, I can give you a very simple and comprehensive explanation of what lies at the heart of the current major political crisis and the protests against the dismissal of defense minister Fedorov in Ukraine.
The reason is that Fedorov's brief time in office, together with the impressive successes of the Ukrainian Defense Forces in the air and at sea, gave the Ukrainian people one thing above all else: HOPE.
Hope that this horrific war, with its appalling sacrifices and monumental heroism, might end in something far better than, at best, the bitter and humiliating "peace" for heroic Ukraine that would certainly be nothing more than a short respite before an even greater nightmare.
It is the hope that good will ultimately triumph over evil, that life will overcome death and light will overcome the dark, that justice truly exists in this world, and that the great vile evil embodied by fascist Russia will be punished for its crimes.
And who knows how history may yet unfold -- perhaps that hope will one day lead us back home, to Donetsk, Luhansk, Mariupol, Melitopol, Berdyansk, or Crimea, so treacherously stolen from us.
And hope is a tremendous force.
I strongly advise no one to stand in the way of Ukrainians who have finally seen a light at the end of the tunnel of darkness and a source of genuine good hope.
"[C]ooling is a hot issue on which the populist right has the better side of the argument. That should unsettle American progressives, who assume the far right is consistently irrational while the left is the party of science. On AC, the opposite is closer to the truth."
I've always thought that the campaign against "ultra-processed" foods was mindless. What the heck does that even mean: the more things you do to food, the less healthy it is? New RCTs and analyses confirm that the stigma is meaningless (it's calories, fiber, & other causes, not "ultraprocessing") and even harmful: it encourages RFKj's MAHA quackery. I suspect that food researchers are subject to class bias: food that poor people like and can afford must be unhealthy. https://t.co/LaVlWVSd9F
The reason large AI companies with virtually unlimited capital, compute, and computer science talent have not transformed biology is very simple.
They do not understand biology.
In biology, the hardest problem is not accessing information. We already have enormous amounts of publicly available data, papers, databases, omics datasets, and experimental results. Much of it remains underutilized. Most of it can be converted into computable formats straightforwardly.
The difficult part is knowing which questions matter.
What do we actually understand? What don’t we understand? Which hypotheses are worth testing? Which experiments would meaningfully reduce uncertainty? Where are the conceptual bottlenecks preventing progress?
These are scientific judgment problems, not database problems.
What biology lacks is not data. It lacks enough biologists with strong quantitative and computational skills who can identify important questions and use available tools to answer them.
Biology is different from coding. The challenge is not retrieving information. The challenge is deciding what information is worth generating in the first place.
Once AI companies recruit enough biologists who know how to identify important questions and how to use quantitative tools to address them, the opportunities will be enormous.
The bottleneck is not the databases. The bottleneck is biological insight.
For four decades the American obesity rate only moved one way: up. The CDC's measured surveys took it from about 15% in the late 1970s past 40% by 2023, every period higher than the last.
Now a different gauge shows it bending. Gallup, which has tracked this since 2008, clocked obesity at 37.0% for 2025, down from its 2022 peak, about 7.6 million fewer adults in three years. The steepest drop hit the 50-to-64 group, down a full 5 points.
What changed wasn't willpower or a new food pyramid. Ozempic-style shots for weight loss more than doubled, from 5.8% of adults in early 2024 to 12.4% in 2025, and obesity fell most in the exact age group using them.
Decades of diet advice never moved this line. One drug class did, in thirty-six months.
The fixable problems get fixed once the tool finally shows up.
@pdonohue1964@nytimes@MTA@GovKathyHochul Maybe the unreasonableness of some of these legacy work rules casts a shadow on the entirety of the negotiating posture. The percentage in itself does not seem crazy.
@GuthmannR I guess this discussion illustrates the challenge with this whole macro development concept. Both stories are plausible, and it’s hard to adjudicate which is true without strong identification.
@jbsteinberg@wakincognitwo But I guess those kinds of papers even if arguably useful wouldn’t get published in a top journal so incentives don’t quite align.
@arindube Hard to argue for the developed world
when debt to GDP ratios are soaring… I doubt this is also the case for developing countries but maybe less clear cut?
@Nemtastic1@asymmetricinfo I agree but is the premise here that writing a take home essay takes conscientiousness rather than “ability”? Seems debatable.