Bonifant Lab

Pediatric oncology research lab of the Johns Hopkins School of Medicine studying cellular immunotherapy

[Bonifant Lab @BonifantLab]

Congrats to @ChristodoulouMD on starting his residency! The lab family misses you!😭😭😭 @MataVorri @RahnamaRuyan @nat_holl @cleebon
#residency #UPMC #sad #jhu #doctor #boatlife

[Ilias Christodoulou @ChristodoulouMD]

Deeply honored to be selected among many talented @hopkinskimmel postdocs to present my research work in the C3PO Johns Hopkins Postdoc Lecture Series. So grateful for the support of @BonifantLab the past 3 years! #CAR_NKs #AML #JohnsHopkins #TheLastDance

[Bonifant Lab @BonifantLab]

Congrats to lab super star Ilias on matching into Internal Medicine at @PittDeptofMed 🥳 🎉 👏

[Ilias Christodoulou @ChristodoulouMD]

Extremely thrilled for the next step in my career as an Internal Medicine resident @PittDeptofMed! Very grateful for everyone who supported me in this journey and especially my fantastic mentor @BonifantLab. Can't wait to join the #UPMC family! @PittIMChiefs @PittGIM #Match2022

[Ilias Christodoulou @ChristodoulouMD]

Very excited to see our latest work on COVID-19 therapeutics with @BonifantLab published in @FrontImmunol. Here we describe the use of the novel BananaLectin-CAR engineered NK cells for the treatment of SARS-CoV-2 infection. #COVID19 #CAR_NK #BananaLectin https://t.co/C8IHLEK3zD

[Bonifant Lab @BonifantLab]

A big thank you to all the other co-authors @BMTriplettMD and stay on the lookout for more cool work out of the @BonifantLab !

[Bonifant Lab @BonifantLab]

Excited to share work out of the lab from Wesley, current grad student, and Challice published in @ASTCT_Journal exploring the impact of disease burden on tisagenlecleucel treatment in B-ALL patients at @hopkinskimmel and @StJude with our friends @AimeeTalleurMD @Kyttaro_Therapy

[Chimeric Antigen Receptor T-Cell (CAR-T) & Gene Rx @CARTTherapy]

Impact of High Disease Burden on Survival in Pediatric Patients with B... https://t.co/YA5JYyyhq5

#CART #bmtsm #CARTcell #immunotherapy #tcellrx #ICAN #CRS #CARTcells #CellTherapy #Gene #Genetherapy
@ASTCT @ASTCT_Journal @SaudiLeukemia @riadelfakih

[Bonifant Lab @BonifantLab]

This real world analysis was a great collaboration between @HopkinsMedicine and @StJudeResearch that we hope will inform current standard of care practices for tisagenlecleucel therapy @NovartisCancer #CART

[Ilias Christodoulou @ChristodoulouMD]

Thrilled to see our new work with @BonifantLab at @hopkinskimmel published in @jitcancer !

[Bonifant Lab @BonifantLab]

Our very own @ChristodoulouMD showing off his great work in the lab at #ASH21 And 1 poster wasn’t enough for our Ilias, he came ready with 2! 🇬🇷 🤩 Ilias and Challice are representing #BonifantLab well in Atlanta

[Ilias Christodoulou @ChristodoulouMD]

It was wonderful to present our work with @BonifantLab
on CAR-NK cell targeting of Acute Myeloid Leukemia and Lectin-CAR engineered NK cells for SARS-CoV-2 clearance at #ASH2021. Honored to be among the Abstract Achievement Award Recipients! #Immunotherapy #CAR_NK #AML #SARSCoV2

[Juan C Osorio MD @juanosoriomd]

@ChristodoulouMD @BonifantLab Congrats Ilias! Awesome work!

[Karen Dixon @KarenODixon]

@ChristodoulouMD @BonifantLab Congrats Ilias; great work :)!

[Bonifant Lab @BonifantLab]

Check out this great work by our very own @ChristodoulouMD 🇬🇷

[bioRxiv @biorxivpreprint]

Engineering CAR-NK cells to secrete IL15 sustains their anti-AML functionality, but is associated with systemic toxicities https://t.co/yzlMLGzNlF #bioRxiv

[Ilias Christodoulou @ChristodoulouMD]

Excited to share our work with @BonifantLab! Here we describe the design and testing of NK cell-specific CARs targeting the CD123 antigen on AML cells. We also enhanced the anti-AML activation of CAR-NK cells with secretory IL15 and explored their in vivo therapeutic potential.

[Bonifant Lab @BonifantLab]

Amazing job by our very own @ChristodoulouMD presenting his work in the lab at #IOYIF21 We are proud of you Ilias! 🇬🇷

[IOYIF @IOYIForum]

Dr. @ChristodoulouMD from @hopkinskimmel presented research findings from his work examining IL15-secreting CAR-NK cells in AML, highlighting enhanced efficacy but lethal toxicity, thereby informing future CAR-NK research efforts. #IOYIF21 #celltherapy #CART

[Max Mamonkin @MaxMamonkin]

Well done Kates! Banana (lectin)-powered CAR T-cells will defeat solid tumors. Malcolm Brenner @CAGTHouston collab with @BonifantLab and U Michigan

[Johns Hopkins Arts & Sciences @JHUArtsSciences]

@HopkinsBio major Wesley Ravich's passion is to work in pediatric oncology and he has done just that since arriving at Hopkins. His work in the @BonifantLab is focused on the field of cellular immunotherapy, which is poised to revolutionize leukemia therapy. #CancerResearch

[Bonifant Lab @BonifantLab]

A fun day at Harpers Ferry with the crew celebrating @aymarps graduation! Enjoy your pool in Florida Andrew!

[Bonifant Lab @BonifantLab]

Congrats to our very own, Andrew Marple @aymarps on his first place finish at today’s Johns Hopkins SOM Trainee’s day! Great job Andrew!