Saudi Leukemia Net

An educational account for hematologists #leusm #lymsm الشبكة السعودية لسرطانات الدم

[مستشفى الملك فيصل التخصصي ومركز الأبحاث @KFSHRC]

#التخصصي ينجح في تطبيق العلاج الجيني لمريض مصاب بفقر الدم المنجلي، عبر تعديل الخلايا الجذعية المكوِّنة للدم لتصحيح الخلل الوراثي المسبب للمرض، ثم إعادة حقنها في جسم المريض، ضمن دراسة سريرية تهدف إلى توسيع الخيارات العلاجية المتاحة للحالات غير المؤهلة للخضوع لزراعة خلايا جذعية من متبرعين.

للمزيد من المعلومات: https://t.co/FNTdZH8M2L

[Pradeep Natarajan @pnatarajanmd]

Very honored to write this review on the genetics of coronary artery disease with Prof H. Schunkert and Sir N. Samani https://t.co/ztgKCcbpkO @NEJM

[Chris Hourigan @DrChrisHourigan]

Genuinely excited to be finally able to fully share the first major output from the MEASURE consortium at #ASH25 #ASH2025 - the largest cohort of paired tumor and remission WGS from patients with AML https://t.co/2WozDIrEtA

[Sanam Loghavi, MD صنم لغوی 🔬🧬 @sanamloghavi]

🚨 This is it people … you heard it first at #ASH25 🚨
ELN #MRD 205 guidelines are in press in @BloodPortfolio
Bad news: It’s more complicated than before… 🤯
Good news: there’s an app for it 😉
https://t.co/S0p6gDIQmk

[Hematology Review @HematologyTweet]

Anticoagulation strategies in hematologic malignancies with thrombocytopenia

Very nice summarised figure
#ASH25
@Ruah_Mahmoud
@dhoughton

[Transplantation and Cellular Therapy Journal @ASTCT_Journal]

This retrospective single-center study evaluates high-dose melphalan followed by busulfan/fludarabine conditioning in elderly patients with active #AML. Three-year overall survival was 44% and 40% of patients remained relapse-free. https://t.co/0jNuBchDXw

[Bruce Levine, Ph.D. 🇺🇦🥼🔬🧬🧪💉 @BLLPHD]

The description of regulatory T cells and connection to FoxP3 is a beautiful story for #Science and the #NobelPrize

[مستشفى الملك فيصل التخصصي ومركز الأبحاث @KFSHRC]

نجح #التخصصي بالرياض في علاج أول مريضة باستخدام الخلايا التائية المعدلة وراثياً، والمصنّعة محلياً، وذلك ضمن المرحلة الأولى من بحث سريري يستهدف مرضى سرطان الدم الليمفاوي الحاد المقاوم، في إنجاز نوعي يسهم في توطين العلاجات الجينية والخلوية بالمملكة.

لمزيد من المعلومات: https://t.co/EQV5pYbHtP

[SPAENG @Spa_Eng]

KFSHRC Reinforces Global Leadership as Early Adopter of Advanced Cell and Gene Therapies.
https://t.co/H7ZpW1kZT0
#SPAGOV

[MBC أخبار @MBC24News]

مدير قسم الأبحاث السريرية بمستشفى الملك فيصل التخصصي د. رياض الفقيه يشرح سرطان ابيضاض الدم اللمفاوي الحاد ومدى خطورته

#نشرة_التاسعة

#MBC1

[Transplantation and Cellular Therapy Journal @ASTCT_Journal]

The effects of graft cryopreservation on patient outcomes in allogeneic HCT remain unclear. This UK study of cryopreserved vs. fresh allogeneic HCT found no statistically significant difference in overall survival at 12-month follow-up. For more: https://t.co/NWTq6pmwFk

[Chimeric Antigen Receptor T-Cell (CAR-T) & Gene Rx @CARTTherapy]

Haplo-stem cell transplant post liver transplantation to cure sickle cell disease with related liver dysfunction: a case series | Communications
⁦@NatureMedicine⁩ ⁦@KFSHRC⁩ ⁦@KFSHRC_Research⁩

The 1st case series...
Proud of our team https://t.co/8oC6tobGco

[التواصل الحكومي @CGCSaudi]

ليست مجرد خلايا تُزرع، بل قصة تُكتب؛ الدكتور محمود الجرف غدًا في المنافس العالمي.

[Hagop Kantarjian,MD @DrHKantarjian]

There have been major advances in #ALL therapy over the last decade. Check out our review just published in @JournalCancer discussing these advances & revolution in adult ALL therapy
@MDAndersonNews #Leukemia
@NitinJainMD @NicholasShortMD Jabbour
https://t.co/wIKVKAubYG
#leusm

[Talha Badar @TalhaBadarMD]

Project EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia https://t.co/YRlQ3N7OW6

70 cases of B-cell #ALL with lineage switch after immunotherapy (anti-CD19) to AML or mixed phenotypic leukemia.
Dismal outcome with median OS 4.9 months.
#leusm @BloodPortfolio

[Talha Badar @TalhaBadarMD]

https://t.co/1xKA5q1i1H

Spectrum, prevalence, and clinical correlates of PPM1D mutations in patients with clonal hematopoiesis and clonal cytopenias: highlights from #EHA2025 #EHA25

[Chimeric Antigen Receptor T-Cell (CAR-T) & Gene Rx @CARTTherapy]

I can't understand e.g. if the stem cell lab refused to release the specifications of cellular therapy product e.g. CD34, TNC,etc...
Where is the quality?
#Novartis more practical in the this issue

[Bruce Levine, Ph.D. 🇺🇦🥼🔬🧬🧪💉 @BLLPHD]

🚨NEW - In vivo CAR T cell generation to treat cancer and autoimmune disease @capstantx direct delivery of mRNA-encoded CARs to CD8+ T cells in mouse & NHP models shows tumor control not only in blood, but also tissue. Immune reset seen at B cell recovery https://t.co/8TunddD8Vp

[Jordan Gauthier @drjgauthier]

CREM de la CREM

[وزارة الصحة السعودية @SaudiMOH]

عذرًا:
هذا المصعد خاص بالإسعاف!

#حج_بصحة
#يسر_وطمأنينة