Incredibly excited & honored to receive an @ERC_Research Consolidator Grant to study epigenetic regulation of lineage specification in the developing cortex. Big thanks to my amazing team @Bonev_Lab, mentors & collaborators, @PioneerCampus and @HelmholtzMunich#ERCCoG
New #preprint alert from our lab!
We investigated how cellular context influences TF-driven epigenetic rewiring during neuronal differentiation.
Check it out here: https://t.co/0F3tnbZ0Fr
Excited to have contributed to this @Bonev_Lab and Götz Lab collaboration 🚀
Published now in @NatureNeuro!
https://t.co/BwEy0mFKrL
“Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1”
@Boyan84@HelmholtzMunich
Happy to see our new story published. 3 types of cortical Radial Glia Cells revealed: alpha, beta and gamma, with different amplificative behavior and involved in different cell lineages, that run together and in parallel in different germinal layers. Ferret is a superb model (1)
🔬 Exciting News Alert! 📢 Our cell fate decision map 🧠has just been published in @NatureCellBio! 🎉
A real privilege to work with Laure, @Alex_Baffet and all co-authors!
📃Interested in learning more? Full paper here: https://t.co/Uiby914HRZ
#organoids@institut_curie
Diving deeper into the genomics of osteoarthritis 🧬 Pleased our work on the first 3D map of chromatin interactions in primary osteoarthritis chondrocytes is out:) @G_Orozco_C
https://t.co/cijyi6OQRc
𝗜𝗻𝘁𝗲𝗿𝘃𝗶𝗲𝘄 with 𝗣𝗿𝗼𝗳. 𝗠𝗮𝗿𝗶𝗮-𝗘𝗹𝗲𝗻𝗮 𝗧𝗼𝗿𝗿𝗲𝘀-𝗣𝗮𝗱𝗶𝗹𝗹𝗮 about her enthusiasm for 𝗲𝗽𝗶𝗴𝗲𝗻𝗲𝘁𝗶𝗰𝘀 & her idea of leading a powerful team!
👉 Be inspired by her ideas by reading her interview & watching her video statements: https://t.co/CnjNU1ndtb
It is out 😲 - 🥳
a tour-de-force by Nakatani-san + tremendous work from all co-authors -
lots of exciting new biology - enjoy the reading 👇👇- looking forward to comments & feedback
https://t.co/rfsO79mN1U
👩🔬👨🔬✨ This work not only offers a comprehensive view of epigenetic rewiring during human brain development, but also introduces 3DRAM-seq as a powerful tool for investigating cell-type-specific gene regulatory networks. #ScientificAdvancement#BrainResearch