Bran D Le

studying gene regulation shaping human brains in UNC Chapel Hill's bioinformatics and computational biology PhD program (he/him)

[Bran D Le @BrandonDLe]

@sj_marzi @UKDRI @ImperialBrains @ImperialMed Thanks for inviting me to share our science!

[Sarah Marzi @sj_marzi]

Another awesome #neurogenomics seminar released on YouTube: catch @BrandonDLe's fantastic talk on wnt activity dependent molecular QTLs here 👇
https://t.co/tzxSen5IlY

@UKDRI @ImperialBrains @ImperialMed

[Bran D Le @BrandonDLe]

@sj_marzi @jsteinlab @uncneuro @UKDRI @UKDRI_ECR @ImperialMed @ImperialBrains Thanks for having me!

[Nana Matoba @NanaMatoba]

Excited to share our new preprint, where we investigated context-specific gene regulation and QTLs by stimulating 🪄⚡️ the Wnt pathway in human neural progenitor cells🧠 (co-led with two wonderful grad students @brandonDLe @jmvalone4 in @jsteinlab) https://t.co/CNDbm2tvnR 1/🧵

[Bran D Le @BrandonDLe]

🧠Our paper describing common genetic effects on lithium-induced neural progenitor proliferation is out @BiologicalPsyc1!🧠 Many thanks to @JustinWolter8 @NanaMatoba @mikelaff @NilAygun8 @danliang_unc @Songlaboratory @JoePiven @MarkZylka and @jsteinlab!
https://t.co/rqE4tH91Iq

[Bran D Le @BrandonDLe]

In our new preprint, the Stein Lab discovered common genetic variation significantly associated with human neural progenitor cell’s (hNPCs) proliferative response to Lithium! https://t.co/KUu428f1iC 1/9

[Bran D Le @BrandonDLe]

@lswhiteh Thanks, Logan!

[Bran D Le @BrandonDLe]

Thanks to an awesome https://t.co/t6GzlkMazp team led by @jsteinlab and featuring Justin Wolter @NanaMatoba @mikelaff @NilAygun8 @danliang_unc Kenan Courtney @JoePiven and @MarkZylka ! 9/9

[Bran D Le @BrandonDLe]

In our new preprint, the Stein Lab discovered common genetic variation significantly associated with human neural progenitor cell’s (hNPCs) proliferative response to Lithium! https://t.co/KUu428f1iC 1/9

[Bran D Le @BrandonDLe]

…or in fetal NPCs, genetic effects on lithium-sensitive GNL3 expression and in turn proliferation might influence neurodevelopment to affect complex brain traits like intelligence and neuropsychiatric disorder risk. 8/9

[Bran D Le @BrandonDLe]

@NickyPenttila @jsteinlab Whoops, I'm a bit of a twitter novice. The image is just a screen grab of my poster info. Are these sorts of images typically flagged? How do I avoid this? Thanks for alerting me.

[Bran D Le @BrandonDLe]

Check out research from the @jsteinlab this afternoon at #SfN21 from 3-4pm EST. Looking forward to discussing common human genetic variation modulating lithium-induced neural progenitor proliferation with the world!

[Bran D Le @BrandonDLe]

I wrote a new piece for @UNC_SWAC about how the summer's hottest party drug owns your brain. But is it safe for children? Find out here: https://t.co/bskqAYq7Zc

[Julián Castro @JulianCastro]

Teachers shouldn’t be forced to buy their own supplies while our police departments purchase combat vehicles.

[Joshua Hall @jdhallphd]

I am seriously all for no weapons, but this feels like a double standard. Remember rocket launcher guy in the Raleigh Subway (sandwiches) two weeks ago protesting masks and opening barber shops?