Wadsworth

Postdoc @karolinskainst
PhD 🎓 Hypoxia Biology 🧬 Hiking 🌄 Coffee ☕️ Canadian 🇨🇦 in Stockholm 🇸🇪

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

[Marianne Koritzinsky @MKoritzinsky]

ADO (cysteamine dioxygenase) is a unique enzyme whose substrates include both proteins and metabolites! We were curious about the role of ADO in cancer and normal cells. Excited to share our paper published today: https://t.co/nT386rdz6Z

[John Loeber 🎢 @johnloeber]

I would love an ELO-based restaurant ranking system

Yelp reviews aren’t very useful. Everything is 3.5 - 4.5 stars. Tells me nothing. Same for Google Maps. The 0-5 scale just doesn’t get used properly because of social norms toward high ratings.

What would work much better is…

[. @gamonasterioo]

The value of ‘wasting time’ on deep thinking is often overlooked in a scientific ecosystem increasingly tainted by Wall Street’s productivity mindset.

https://t.co/hNTA74DNOr

[Wadsworth @BrennanWads]

Congrats to Hailey, Ivan, and Arman on the great work. Happy to be involved in this PET radiomics project

[Arman Rahmim @ArmanRahmim]

After significant efforts led by @IvanKlyuzhin, our paper is finally published: "Relating Macroscopic PET #Radiomics Features to Microscopic Tumor Phenotypes Using a Stochastic Mathematical Model of Cellular Metabolism and Proliferation"
https://t.co/vnVcIdxgpe
Hailey Ahn et al.

[Randall Munroe @xkcd]

Good and Bad Ideas https://t.co/cceFdBWKHt

[Pedro Veliça @pedrovelica]

Turns out AI stands for "appearance of intelligence".

[Pedromics @pedromics]

And for those still looking, remember that for there is a TCR for every antigen-MHC complex out there.

Happy Valentine's.

[Neil Renic @NC_Renic]

Two kinds of academic feedback:

[Robert Insall @robinsall]

Cell seems to have 100% morphed into the "journal of scRNAseq atlases". Apparently no other modes of science are accepted...

[Iosifina Foskolou @ipfoskolou]

Are you looking for a PhD programme on tumour immunology and immunotherapy?

We are hiring!

Sanquin Research is looking for a PhD candidate who will join the Foskolou lab to investigate novel ways to make CAR-T cell therapy better for solid tumours.

https://t.co/K67DThSyzw

[Wadsworth @BrennanWads]

Great and thorough work from @pedrocunha37 Plenty of insight for the importance of oxygen during CD8+ T cell activation

[Pedro Cunha @pedrocunha37]

It’s finally out 🎉! Our study on how low oxygen levels sensed by CD8+ T cells during activation modulate T cell function and can be harnessed to improve immunotherapeutic efficacy @eLife https://t.co/K1GFED3pig. Here's the tweetorial ⬇️⬇️⬇️(1/n)

[Randall Munroe @xkcd]

K-Means Clustering https://t.co/dgV9ulStUb

[Wadsworth @BrennanWads]

More interesting insights into T cell biology from the @camkiphysiology group, this time NO synthesis. And of course the importance of oxygen and hypoxia! Great work @pedrocunha37 and @pedrovelica

[Cancer Immunology Research @CIR_AACR]

Online First:
Infiltration of tumors is regulated by #Tcell-intrinsic nitric oxide synthesis, by @pedrocunha37, @camkiphysiology et al.
https://t.co/mzrbC2KFrj
@ipfoskolou @BrancoGroup @pedrovelica

[Randall Munroe @xkcd]

Methodology Trial https://t.co/iJVXcqe8Nc

[Wadsworth @BrennanWads]

Eleanor and the @camkiphysiology group show that glutarate is a regulator of cellular metabolism and aKG dependent dioxygenases with significant effects on T cell function. https://t.co/XNO4MGab4q

[Wadsworth @BrennanWads]

Congrats to everyone involved!

[BioArcticAB @bioarcticab]

Lecanemab phase 3 Clarity AD study in early Alzheimer’s disease meets primary and all key secondary endpoints with high statistical significance https://t.co/tkK0y2vHXo

[Wadsworth @BrennanWads]

@KevinBennewith @LdeCotret Congrats @LdeCotret!!

[Wadsworth @BrennanWads]

Eosinophils modulating metastatic tumor growth
Great work @RachelCederberg