Brooks Leitner

Interested in how a better understanding of science and society can improve our health. Investor @PsyMedVentures

[Brooks Leitner @BrooksLeitner]

@SFIPress Todays the day... fingers crossed

[Matias Serebrinsky @matisere]

Sometimes we come across a breakthrough that stops us in our tracks. That happened when we discovered temporal interference (TI), a noninvasive way to stimulate deep brain regions.

This could have a massive impact on many neuro conditions.

We spoke with @nir_grossman, a leading TI researcher, to understand how this works.

Link to episode in next post

[Brooks Leitner @BrooksLeitner]

@sharenarice Busy busy!!! Hope you have good in flight entertainment strategies

[Brooks Leitner @BrooksLeitner]

Builds on insights from the 2.6x increased likelihood of drug development success for targets with genetic evidence

https://t.co/CUIZAxJUDB

[Brooks Leitner @BrooksLeitner]

For founders building an AI or biotech company and want a pharma partnership.

Tips on genetics, acquisition considerations, and when to partner with AI companies

Three Pieces of Advice to Biotech Start Ups from a Neuroscience Biopharma Exec

https://t.co/zADpw8CwI7

[Brooks Leitner @BrooksLeitner]

Is Techbio Ready for Neuroscience?

Techbio companies are using AI in numerous ways to develop new drugs; what approaches will work for neurologic and neuropsychiatric diseases?

https://t.co/9BRVy8CQ9j

[Brooks Leitner @BrooksLeitner]

Three years ago, Whoop hit a $3.6B valuation. This month, Oura joined the club with a $5B valuation.

Next gen consumer health devices will focus on the brain ...

What features would you want?

https://t.co/SrsCJTsA0J

[Alex Kwan 關進晞 @kwanalexc]

There are many nuances regarding the structural neural plasticity associated with antidepressant drugs. 💊🧠

We share our thoughts here in a @NatRevNeurosci article, led by @ItsClaraLiao and included co-authors from Conor Liston’s lab at @WCMPsychiatry

https://t.co/qCu6Bok2wr

[Brooks Leitner @BrooksLeitner]

Read more about surrogate endpoints for clinical trials, the challenges for CNS, and Biogen's anti-amyloid drug as a fascinating case study

[Brooks Leitner @BrooksLeitner]

Does neuroscience stand to benefit from better surrogate endpoints?

Surrogate endpoints hold the potential to increase the odds of clinical trial success and patient benefit. Yet there are extremely few in neurological and psychiatric indications...

https://t.co/uf4ehGH3C8

[Brooks Leitner @BrooksLeitner]

Key Lessons:
- What measurements (data) you feed into your statistical models really matters
- Microbiome status has an important mediating variable which should be included in future studies
- Your microbiome is a product of your body's ecosystem (feed it well!)

[Brooks Leitner @BrooksLeitner]

Mini 🧵on New Microbiome Research:

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations: Cell https://t.co/jZdd4s7x8L

[Brooks Leitner @BrooksLeitner]

This total microbial load was associated with factors like age, sex, diet, date since antibiotics treatment and also, how long your stool remains in the GI tract.

[PsyMed Ventures @PsymedVentures]

NEW Business Trip Episode “Genetic Medicine for Brain Health” with @Dana Watt of @Breakout Ventures.

Listen here: https://t.co/yHe4QgEPGb

[Matias Serebrinsky @matisere]

New Business Trip epi on genetic therapies for mental+brain health.

We've been thinking for a while about the place of these therapies in brain and mental health. They don't just manage symptoms; they address underlying issues.

Saying they go to the source is too simplistic, but they might go to some of the sources.

So, we invited one of my favorite VCs, Dana Watt from @breakout_vc, to discuss the science, business models, challenges, and the road ahead.

Listen here: https://t.co/LyOmOo1HP9

[Yale PCCSM @YalePCCSM]

🚨New publication alert!🚨
Read the latest from #YalePCCSM's Drs. Phillip Joseph, Jose Gomez Villalobos, and Indy Singh et al at the link below 👇🏻
"The metabolic and physiologic impairments underlying long COVID associated exercise intolerance"
https://t.co/XmXGYQA4ux

[Brooks Leitner @BrooksLeitner]

How much energy does it cost to study for a test? Or remember what you did last weekend?

Why is this harder as we age? What can we do about it?

Read more if you're interested in the intersection between metabolism and neuroscience: https://t.co/9Yh6KgR7Hn

[Brooks Leitner @BrooksLeitner]

"The day science begins to study non-physical phenomena, it will make more progress in one decade than in all the previous centuries of existence"

- Nikola Tesla

[Physics In History @PhysInHistory]

Consciousness cannot be accounted for in physical terms. For consciousness is absolutely fundamental. It cannot be accounted for in terms of anything else.

- Erwin Schrödinger