Center for Antibody Technologies

Research group focused on developing affordable biotherapeutics and diagnostics for neglected tropical diseases based on monoclonal antibodies

[DTU @DTUtweet]

A promising #snake venom #antibody that failed testing is good news for developing a broad-spectrum #antidote. New research from i.a. Danish & Costa Rican scientists in @NatureComms. @CAT4Science @UniversidadCR @AndreasLaustsen @CVSoerensen #Immunology https://t.co/u2OuPMACMr

[Center for Antibody Technologies @CAT4Science]

Thanks to all collaborators and funders including @DTUtweet @DTUbioengineer @DTUBiosustain @wellcometrust @VILLUMFONDEN @novonordiskfond @ERC_Research @UniversidadUCR

[Center for Antibody Technologies @CAT4Science]

Exciting News! - Yesterday our newest paper was published in @NatureComms by @CVSoerensen, @AndreasLaustsen and many more. The study unveils highly surprising research findings on snakebite envenoming therapies that call for caution. Full study: https://t.co/40RU4J2Qg2

[Center for Antibody Technologies @CAT4Science]

Thanks to Michael Hust and Theam Soon for making us part of this, to @CAT4Science team, @DTUbioengineer, @DTUtweet, @AndreasLaustsen for your support, to employees at @BioInvent and @mats_ohlin for the fruitful discussions, and @wellcometrust and @ERC_Research for funding!

[Center for Antibody Technologies @CAT4Science]

We are happy to share the publication of a new book on #phage display in @SpringerNature, where Tulika and @AnneLjungars describe #deep mining methods for the discovery of #rare #antibodies.

https://t.co/yfJAqsXbTy

[Center for Antibody Technologies @CAT4Science]

Typically, #whole cell selections result in discovery of antibodies against highly expressed cell surface receptors. Here, we present detailed protocols on phage display selections, utilizing #depletion or #blocking, for discovery of #rare #antibodies against multiple targets.

[Center for Antibody Technologies @CAT4Science]

The sun is shining in Denmark and besides our passion for science we also love and enjoy moments together by having a barbecue or flowing down the river on a canue! Have a look at some of our moments together 😊

[DigitalBiotechnologyLab @DigBioLab]

🔬🌍 Exciting PhD Opportunities in #DataScience and #Biosustainability at @DTUtweet

https://t.co/V6trtTdbwK

[Andreas Laustsen @AndreasLaustsen]

Podcast: A few months ago, I had the pleasure of doing this @REBBLS Podcast with @JornEmborg, where I got to tell about my career as both an #academic and #biotech #entrepreneur, as well as how to bridge these two worlds: https://t.co/bNbBKYtByc

[Center for Antibody Technologies @CAT4Science]

Further, we thank @DTUtweet, @DTUbioengineer,@VILLUMFONDEN, @wellcometrust, @ERC_Research for the support to realize this project.

[Center for Antibody Technologies @CAT4Science]

Last week @jack_wade6 successfully defended his PhD thesis about "Engineering and structural characterization of cross reactive, pH sensitive antibodies against long chain alpha-neurotoxins". Thank you for the last three years and we wish you can continue your successful path!🥳

[Center for Antibody Technologies @CAT4Science]

We are happy to share a new paper in @CellRepMethods by @AnneLjungars about her previous work at @BioInvent and @lunduniversity regarding #antibodydiscovery using #computational modeling combined with #antibody #phage display and #NGS
https://t.co/OJHkpZ9jwu

[Center for Antibody Technologies @CAT4Science]

We have prepared a thread about our new #preprint about pH-dependent binding antibodies and how cool this is on #antivenom development. Thanks to
@ERC_Research
for the generous funding and to all our colleagues
@DTUtweet
@DTUbioengineer @Oslounivsykehus
https://t.co/hBezkgbzod

[Center for Antibody Technologies @CAT4Science]

We are excited to share our #preprint “Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library”!
Read: https://t.co/6Ul3ADEsg0

[Center for Antibody Technologies @CAT4Science]

Thank you @DTUbioengineer @AndreasLaustsen @LLedsgaard @markthebanana @AndersenJT and @CAT4Science team for your help with this study! 🧬🥽

[Center for Antibody Technologies @CAT4Science]

We are excited to share our #preprint “Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library”!
Read: https://t.co/6Ul3ADEsg0

[Center for Antibody Technologies @CAT4Science]

Our study shows that histidine doping may not always be necessary to achieve pH-dependency in antibodies. Plus, given the high diversity available in a naïve antibody library, it can likely be applied to discover pH-dependent antibodies against a wide range of antigens!