Many thanks to everyone who contributed to a great 2 days of cross-disciplinary #AMR discussions at our @GW4Alliance networking event. Lots of new connections made between members of the @MilnerCentre @BristolAMR @CardiffMMI@ExeterMicrobes@MRCcmm and many others!
My FIRST #preprint is in the world! See our #research into #pandemic E. coli ST131👉 https://t.co/HCUgRi7lfh
#Genomic epidemiology reveals geographical clustering of multidrug-resistant E. coli ST131 associated with bacteraemia in Wales, UK | @medrxivpreprint
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Fantastic to see this work on @biorxiv_micrbio! A combination of my thesis and postdoc work to explore polyyne biosynthetic pathways and discover a #Pseudomonas metabolite we called protegencin!
Great study combining #bioinformatics, #genomics, and natural product chemistry
Our paper on the molecular basis for regulation of antibiotic biosynthesis in Actinobacteria by bacterial hormones has just been published in Nature (https://t.co/OyYHtZCEUs). Great collaboration with @CorreLabo@warwickuni and colleagues @MonashBDI.
Excited that this paper from my first postdoc position at @CUBiosciences@CardiffMMI is published! Working with #AlgiPharma to explore the application of microbiota analysis to clinical trials for cystic fibrosis lung infection. @MicrobeTweets
https://t.co/2WbB4bhe3d
A collaboration to characterise 2 well-known Bacillus biocontrol strain genomes has led to my debut in Bacillus genomics with the biocontrol agent B. velezensis, exploring antimicrobial metabolite gene clusters across 292 genomes @MicrobioSoc@CardiffMMI https://t.co/mXSroxJftx
Description of a rapid screening method of specialised metabolites, with antibiotics used as inducers of known and uncharacterised natural products in Burkholderia
https://t.co/612NW27IRH
Some great news for a Friday! Work carried out by @cardiffmet student @HeyImNikki in collaboration with @CardiffMMI is now out! https://t.co/Zpeo9kIw98
Our paper on discovery and biosynthesis of gladiostatin, the first glutarimide antibiotic from Gram-negative bacteria, has just been accepted for publication in @angew_chem and will be published back-to-back with a related study from @Hertweck_Lab. See https://t.co/ZDEAnTfmDC.
We are recruiting for someone to join the team running CLIMB in Cardiff. Opportunity for someone with an IT background who wants to develop new skills or bioinformatics postdoc/researcher who wants a change in direction: https://t.co/fvPLzeWxZR
Collaborative article with Cardiff University School of Pharmacy and industrial partner L'Oréal examining efficacy and mode of action of preservative ethylzingerone against Burkholderia
• Transposon mutagenesis
• RNA-sequencing
• MIC/MBC analyses
https://t.co/shnc683XkC
Recent study in collaboration with University of Mysore on the culturable endophytic bacterial diversity of medicinal plants from the Western Ghats, India
• 16s rRNA diversity
• Phylogenomics
• ANI analyses
• AntiSMASH analysis
https://t.co/GWcU15ZdaS
Congrats to Yousef Dashti, Ioanna Nakou and Xinyun Jian, whose paper on the discovery and biosynthesis of a new class of lipodepsipeptides in Burkholderia gladioli has just been published alongside a similar study from @Hertweck_Lab in @angew_chem. See https://t.co/oFa5DTBwz1.
Massive congratulations to @edcoakes on passing his viva this morning by zoom! Best of luck with the new job, and an in person celebration will be organised once it's safe to do so!