Pelacarsen
*hepatocyte-directed antisense oligonucleotide
*Designed to lower Lipoprotein(a)
*selectively binding to the messenger RNA (mRNA) transcribed from the LPA gene, blocking the production of Lipoprotein a
Don’t miss TRIAD at #HRS26. Our team is grateful to share a full lineup of presentations highlighting new work and scientific progress in arrhythmia research, digital health, and AI. Proud of this amazing team and excited to learn, connect, and exchange ideas with everyone here.
#Migraine with aura is associated with increased #cardiovascular risk:
MI: HR 1.36 (95% CI 1.23-1.51)
Ischemic stroke: HR 1.35 (95% CI 1.03-1.78)
Hemorrhagic stroke: HR 1.43 (95% CI 1.07-1.92)
CV mortality: HR 1.27 (95% CI 1.14-1.42)
Data are stronger in women.
Original Article: Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation (CLOSURE-AF trial) https://t.co/ZI5Ml29Dyq
Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? https://t.co/1Mnfv20Z39
#Cardiology#AFib
When it comes to redo ablation, timing matters.
@MassadChristian showed that early repeat ablation is associated with ↓ MACE, ↓ HF incidence, and ↓ AF progression, real-world data pushing us toward earlier intervention strategies.👏 #ACC26@nmarrouche
Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: https://t.co/qAMC2o36Mi
Editorial: Left Atrial Appendage Closure — Another Overused Method in Cardiology? https://t.co/KyOWdblUR3
Dr. Fischer means a great deal to so many of us. An outstanding physician, teacher, and person who guided many #IMG, myself included, as we found our path in the US. Seeing him now win an #Oscar for All the Empty Rooms is incredible and so well deserved. Proud! 💪🏻
Dr. Marashly presented TRIAD - Tulane University MRI data of PFA lesions.
Major take home points:
- Over-ablation may impair LA reservoir function and potentially worsen HFpEF outcomes.
- Lesions stabilize after a month.
- MRI data correspond well to histopathological specimens.
#WAFIB2026 day 3/3: announcement of CASTLE-HFpEF trial, PFA registry, CCB before PFA decrease coronary vasospasm? CCM in HFrEF and AF trials, Amulet 360 LAAO, antifibrotics in atrial remodeling? ICE vs TEE in PFA PVI, CTA vs TEE post-LAAO, and more. Looking forward to #WAFIB2027
Western AF Symposium (Day 2/3): personalized AF care, wearables + ML, AI-driven AF ablation strategies, stroke ppx past “AF-only” toward atrial myopathy phenotyping, HD mapping, etc. Proud to be part of #TRIAD#Tulane strong here thanks to Dr. Marrouche’s leadership! #WAFIB2026