Carter Lab

[Carter Lab @Carter_Lab]

Check out this stunning animation by @janetiwasa (in collaboration with @SamReckPeterson), showcasing our model of how various components come together to form active dynein complexes capable of transporting cellular cargo.

[Carter Lab @Carter_Lab]

Our work on how the lysosomal adaptor JIP3, and regulator LIS1 activate the dynein motor protein is now out in @ScienceMagazine ! https://t.co/pCfhpbQWhO
Many thanks to our reviewers and editor for their valuable input.

[Carter Lab @Carter_Lab]

Excited to share our latest work with the bullock lab! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
https://t.co/UG5is5elDm

[Carter Lab @Carter_Lab]

Check out this exciting new study led by @teix_vanessa revealing that CDR2 is a dynein adaptor and regulates ER sheet organization!!

[Vanessa Teixeira @teix_vanessa]

My PhD work is finally out in @JCellBiol! 🎉
Reach out if you want to know more 😉

[Vanessa Teixeira @teix_vanessa]

My PhD work is finally out in @JCellBiol! 🎉
Reach out if you want to know more 😉

[Carter Lab @Carter_Lab]

A one day meeting on Friday 6th December covering all aspects (and scales) of Structural Biology. 
Lots of talk slots to be selected from abstracts. 
Deadline for abstracts is this Friday (15th Nov).
https://t.co/LiLgzEM7aU

[Carter Lab @Carter_Lab]

Today at #journalclub we looked at the structure of tubulin acetyletransferase bound to the microtubule lumen https://t.co/nSTG2PVwG8

[Carter Lab @Carter_Lab]

A fantastic paper describing a novel mechanism of selective inner mitochondrial membrane removal guided by lysosomal-mitochondrial communication (Dr. Akriti Prashar, @NicolaJGI) #JournalClub https://t.co/qt2qtnmqOy

[Carter Lab @Carter_Lab]

Would you like to work in the MRC-LMB EM facility?
https://t.co/WZo0j8Knyr

[Sam Lacey @samlacey745]

Our paper looking at the structure of retrograde IFT trains is out now! Have a look at the link, or see some of the headlines in this video:
https://t.co/SvADj5wRoh

[Carter Lab @Carter_Lab]

Today at #journalclub we learned how bacteria protect themselves against phage infection by conjugating ubiquitin-like proteins to the phage tails 🤯 https://t.co/IDdFupIc0D.

[Carter Lab @Carter_Lab]

My first PhD student, Emma Hanford (nee Gleave), made some cysteine-lite dynein constructs in 2013. 11 years later, thanks to MinFlux, Joseph Slivka and @Yildiz_Lab they have been used in a nice biorxiv paper. https://t.co/gjRupwBYZo

[Carter Lab @Carter_Lab]

Today in Journal Club - Cross-link assisted spatial proteomics to map sub-organelle proteomes and membrane protein topologies https://t.co/wLpQWEwMhi

[Diorge Souza @diorge_souza]

We're thrilled to share our new preprint: "Evolutionarily Conserved Principles of ESCRT-III-Mediated Membrane Remodeling Revealed by a Two-Subunit Asgard Archaeal System."

https://t.co/1SboXsSj81

[Carter Lab @Carter_Lab]

Today in #journalclub, we discussed the fascinating molecular infrastructure of glutamatergic synapses https://t.co/RCICU6I2Ns

[Carter Lab @Carter_Lab]

Great work from the Dodding and Woolfson labs showing how a designed peptide can activate kinesin in vitro and in cells #journalclub

[Mark Dodding @MarkDodding]

Great to see our work on manipulating kinesin-1 activity using protein design led by @jessica_a_cross in print. In collaboration with @WoolfsonLab. @BristolBiochem @BristolChem @BrisBioDesign

https://t.co/wJXwDxdCxB

[Carter Lab @Carter_Lab]

Very interesting work showing that local translation on axonal ER tubules is mediated by RRBP1 #JournalClub
https://t.co/oSJLTAQTn5

[Ina Harasimov @i_harasimov]

Excited to share our latest study! We discovered that maintaining mammalian oocytes involves extraordinary protein longevity. These proteins support key functions like proteostasis, the cytoskeleton, and mitochondria. Our findings offer new insights into reproductive aging.

[Carter Lab @Carter_Lab]

In yesterday's #journalclub, we had a look at the interesting mechanism by which the UNC-104 motor (Kinesin-3 KIF1A homologue in C. elegans) is stabilised on Rab-3-containing synaptic vesicles - by Bhan and colleagues

https://t.co/I8tCd8DMjw

[Carter Lab @Carter_Lab]

Today in #Journalclub we looked at how Alphafold2 models can guide prospective ligand discovery. A nice study combing in-silico docking and cryo-EM out now in @ScienceMagazine
https://t.co/fBcswMUW66

[Carter Lab @Carter_Lab]

Great work from the McKenney lab reconstituting the KASH protein Nesprin-2 bridging actin to kinesin/MTs #journalclub https://t.co/ul5a1FAYVq

[Carter Lab @Carter_Lab]

Today in #journalclub we delved into the structure of the Flotillin complex. Fascinating insights into how this cage complex could induce membrane curvature and provide a sealed diffusion barrier, connecting membrane systems. https://t.co/JF61UezKLF