Thrilled to share this adventure on how zebrafish elongates its notochord! 🐟 Kudos to Carlos Camacho de la Macorra and @BenSteventon2 for leading it. @CeccarelliAS and I had so much fun modelling & uncovering unexpected predictions...
https://t.co/kpc2VY53sB
We’re also grateful to the Editor and Reviewers for their helpful feedback. We hope this study contributes to a deeper understanding of how cells regain their place in a regenerating organ.
Thanks for reading! 🙌
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This work was made possible by a stellar team: Hernan Arce (PhD), @CeccarelliAS (postdoc), @RepreARG (Diploma student) from my lab and our collaborators Catarina Oliveira, and @MaxYunLab . Huge thanks to all!
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Cells in a regenerating axolotl limb somehow know their place—but how?
In our new paper, we trace the dynamics of positional memory, release open-source code to quantify it, and introduce a theoretical framework for proximalisation.
🧵👇
🔗 https://t.co/KRrYdAEsQu
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A few minutes ago @CeccarelliAS defended his PhD at the University of La Plata! Congratulations Dr Ceccarelli!!!
His defence (in Spanish) at this link:
https://t.co/cbUopbz9v5
🔬Curious about how to achieve an organ-wide regenerative response through locally controlled cell proliferation? Check out our latest preprint, which computationally addresses this problem in the neuromast within the zebrafish lateral line.
https://t.co/rjV1G5v1TS (1/9)
Our new adventure on how Shh+ floor plate cells contribute to spinal cord regeneration along the dorsal-ventral axis in our beloved axolotl is now ready for you! The heroes of this story are my amazing colleagues and friends @lauraarbanas, @LeoOtsuki, @CuraCosta and @Tanaxolotl!!
Our software, ForSys, is finally out as a preprint! I am thrilled to have worked on this fantastic story. I want to thank @hey_jero, @CeccarelliAS, @gbventur, @ksedzinski, Hernán López-Schier, and @Osvaldo_Chara for this amazing journey. Stay tuned for more!
In between the dynamical phases of #tissue growth and decay the tissues are in #homeostasis, which we showed that can be considered a state of #criticality.
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Would you like to know if spinal cord regeneration in the axolotl could be explained by a Reaction-Diffusion signal? If yes, check out our new adventure: https://t.co/2yeURkQh0i #bioRxiv
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Is critical a tissue during homeostasis?
Can a toy Markovian model describing the cells as (stupid) entities that don't "remember" where they are in the cell cycle actually represent a non-Markovian model of tissue growth? Check out our last adventure in bioRxiv!
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