Ribo-ITP enables ribosome occupancy measurements from single cells. Our first application revealed insights into allele-specific ribosome engagement in early development (https://t.co/BA27Bc5ZGh). #RiboITP#singlecell
In our new preprint, we integrated three multiplexed assays of variant effect to profile several layers of gene expression for thousands of variants in COMT! https://t.co/fVXCuX7aot
Intrigued by the potential of Ribo-ITP in uncovering the intricacies of cellular translation? We're seeking motivated postdocs to join our team, we'd love to connect with you!
Ribo-ITP enables ribosome occupancy measurements from single cells. Our first application revealed insights into allele-specific ribosome engagement in early development (https://t.co/BA27Bc5ZGh). #RiboITP#singlecell
Through collaborations, we're applying Ribo-ITP to diverse areas like early mouse limb development, brain organoids, immune cells, and rare cancer cells. If you are interested in adopting Ribo-ITP, here is our step-by-step protocol with video instructions: https://t.co/K3tHOVYgiS
@wu_xuebing Not sure about the timeline for availability as a kit or service. However, several labs have successfully adopted it. If you are interested, we would be happy to help you get started!
We are happy to unveil our latest published work where we describe how the metabolic enzyme, Pyruvate Kinase (PKM), regulates global mRNA translation in human cells. Here's a short 🧵... https://t.co/bA8WotCC6X
Our study showing that Hedgehog signaling is essential for maintaining the early foregut and larynx by preventing EMT was published: https://t.co/6376OAi5dm @eLife. This was led by recent @UTexasILS graduate Janani Ramachandran with help from Hongkai Ji @jihk99 and @ZornLab.
Congratulations to the 2022 @UT_iGEM team for winning the the Best Foundational Advance award at the iGEM Grand Jamboree! They were also a top 10 overall undergraduate team, finalists for Best Presentation and Best Part Collection, and awarded a Gold Medal. @ut_mbs@TexasScience
Our 1st effort into dissecting the crosstalk between #autophagy & other vacuolar trafficking pathways, now out in @JCellBiol Thx to everyone involved!
Hypodermal ribosome synthesis inhibition induces a nutrition-uncoupled organism-wide growth quiescence in C. elegans https://t.co/OgHUEFypP9 @SarinayElif
🌮BioTACOS tomorrow, Mon Oct 17, 2022 9:30 am- 🌮
"RiboBase: A comprehensive databse of ribosome profiling data" by Hakan Ozadam in @CenikLab
Please join in!