Hot off the press! Check out our ‘mutate and conjugate’ paper in @ACSBioMed 🔥
Here we demonstrate that combining site-directed mutagenesis and reactive fragments can be used to rapidly identify selective covalent probes for target validation studies.
Finally, our story about overcoming IDH1 drug resistance is out in @NatureComms. While ivosidenib loses actvity, two other inhibitors (FT-2102, DS-1001B; both in phase 2 trials) retain activity in a cellular environment https://t.co/5AxpdR6IIu
@SchofieldOxford@OxfordChemistry
Yesterday I passed my DPhil Viva! 🎉 The past ~4.5 years in Oxford have been incredible! I've learnt so much and have had the pleasure of meeting and working with so many amazing people! ❤
We've reviewed ~5 yrs of lit info on genetically encoded display generated cyclic peptides with predicted/actual physical properties' links to affinities/crystallisations, structural diversity and impact on biology - out now! https://t.co/3MIlNXvrAO #Peptides#ChemicalBiology
Our report on organising ChemBiOx is online. A lot of work lead to a very successful conference! Many thanks to everyone involved, esp. the organising committee @Grace__Roper @RaphaelRe1@AdamMThomasChem
Stephanie Lovell-Read, Tobias John.@OxfordChemistry
https://t.co/qOQ3K1Iqn6
Organised @ChemBiOx, first Oxford student-led Chemical Biology conference with this great organising committee. Exciting science! Amazing experience! @OxfordChemistry
Congrats and thanks to the Oxford-GSK-Crick PhD students for throwing a fantastic conference @ChemBiOx in Oxford. Great to see Emma Grant and Ross Thomas from GSK ChemBio picking up prizes for their talk and poster respectively.
We've thoroughly enjoyed our time in Oxford representing @Leicesterchem@LeicStructBio at @ChemBiOx alongside colleagues from Hudson and @hopkinson862 groups. Lots of amazing research in a stunning setting. Thanks for the invite!
Well, what an incredible 2 days that was! Great guest lectures and extremely high quality science from the students presenting work 👨🔬👩🔬 Thank you for coming along and supporting the event, the feedback was incredible! Stay tuned for some photos from the event
Paul Fish @ARUK_UCL_DDI kicks off @ChemBiOx fascinating insight into the way chemical biology interface research making breakthroughs possible & changing lives of everyone affected by dementia