Did you think that MET oncogene was only a tyrosine kinase? Check out our new research paper revealing an unsuspected enzymatic activity of the receptor. Online soon at the special issue of IJMS... @IFOMresearch@AIRC_it @fpoirccs
Mutated MET∆14 kinase is not constitutively active but requires HGF. The response to the ligand is stronger and long-lasting, protecting cancer cells from apoptosis and driving invasive growth. @IFOMresearch@AltintasDogus@Comogliogroup@airc_it
https://t.co/hASW2cI30T