UNIMI research team is involved in inter-disciplinary projects, going from genomics, NGS and molecular evolution to machine learning and mathematical modelling
@MartinJLercher@67250Old@ItaiYanai@ScienceMagazine I think it holds. If interested in the theoretical basis, I will give a seminar tomorrow online, the zoom link is available by Jindrich Brejcha, https://t.co/Krvhf7MBWt or write to me [email protected] and I will forward it.
@rravi@ItaiYanai@ScienceMagazine@MartinJLercher well, there are many papers saying this. Only, this got published on Science. Rocha did a lot about this. But some of those patterns are somehow known since Sharp and Li in 88. What is really new, is the theoretical framework that can explain it. A draft: https://t.co/DH39pAj42Y
@ItaiYanai@ScienceMagazine@MartinJLercher Very interesting! I take the occasion for advertising my seminar online tomorrow (April, 15, 1:00 pm), about models of interaction of DNA replication and gene expression with theoretical expl. for what they find in the paper. zoom link contacting https://t.co/Krvhf7MBWt
Reading lots of papers about scaling laws in bacterial growth. But, why no one has considered that variance is also introduced through the changes in copy number introduced by DNA replication?
https://t.co/dE59gUsbsj
https://t.co/SZHkB6WjoH
https://t.co/MQhMxojDeX
Congratulations to @dendenesara and @EmanueleBiondi5 for this important work. It was a long and tiring process, but it ended in the best possible way! Sinorhizobium meliloti FcrX coordinates cell cycle and division[...] https://t.co/0iUFXCrSgI
@schwabpa maybe you are right, in general you should not trust names, and use sequences, but this is normal to me. But, I am writing because the picture is really appalling and wrong. the generating AI does not even know that there are 10 bases per full turn, in DNA.
It was time! After two revisions at @MolBioEvol , and the incomprehensible decision to reject it based on mysterious simulations performed by the reviewer, we are proud to announce that @mSystemsJ liked it!
A novel hypothesis on the origin of operons:
https://t.co/itTfmKdBgY
Paul Dirac explains the deep connection between mathematics and theoretical physics, highlighting how mathematical beauty often guides the discovery of new physical laws. ✍️
very easy to get fascinated by seeing things. I used to spend hours decorating my homology networks back in 2006-2008 but it is much more rewarding to exploit network theory to extract non trivial information about the biological system. So, go on!
Fascinated with graph theory and networks 😍🤯
Here a nice clustering of phages at the family level 👌
Planning to apply it to many more #genomics things 💪
#bioinformatics#microbialgenomics
“Man is the most insane species. He worships an invisible God and destroys a visible Nature. Unaware that this Nature he’s destroying is this God he’s worshiping.”
-- Hubert Reeves (1932 - 2023)
He would have turned 92 today. He passed away last year in Paris.
@razoralign I think you miss references to similar works. It is becoming increasingly common to realize that people nowadays do not pay attention to previous works. this is not entirely new. we worked on the same kind of graph in 2012. we called them gene neighborhood graphs
76 years ago #Today, Claude Shannon published the article 'A Mathematical Theory of Communication', cited over 100,000 times, which is rare for a scientific article and gave rise to the field of information theory.
In a blog post, she tells the story of the reaction she received when she pointed this out to her (tenured) professor at the time, and to others. She was basically told not to waste her time: "a lot of the scientific literature has problems". https://t.co/QRw1SX3H9T 7/
My book Interpretable Machine Learning has been career-defining.
Even though the book is available on the web for free, many have supported me by buying the ebook or paperback, which ultimately helped me become a full-time writer.
I'm grateful for all your support 🙏