Scientists just made 50-year-old skin cells behave like they’re 20 again.
Researchers at the Babraham Institute in Cambridge have developed a groundbreaking method to reverse the biological aging of human skin cells by approximately 30 years, all while keeping them as fully functional adult skin cells.
The team used a carefully controlled, short-term version of the Nobel Prize-winning Yamanaka reprogramming technique. By exposing adult skin fibroblasts to a specific set of reprogramming factors (the Yamanaka factors) for just 13 days—and then stopping the process early—they successfully “reset” many molecular markers of aging without pushing the cells all the way back to a stem cell state.
After this brief treatment, the rejuvenated cells displayed a dramatically younger profile: their epigenetic clock (a measure of chemical tags on DNA that tracks biological age) and their gene expression patterns (the transcriptome) closely resembled those of cells from much younger individuals.
Even more impressively, the cells behaved younger too. The treated fibroblasts produced significantly higher levels of collagen—the protein essential for skin firmness, elasticity, and wound healing—and they migrated faster to close an artificial “wound” in laboratory dishes compared to untreated older cells.
The researchers also observed reversal of age-related changes in genes associated with diseases such as Alzheimer’s and cataracts, suggesting the technique could have broader therapeutic implications.
While this work is still in its early stages and the precise mechanisms remain under investigation, the findings open exciting possibilities: one day, scientists may be able to selectively rejuvenate aging cells in the body to enhance tissue repair, improve healing, and potentially slow or mitigate some effects of age-related diseases—without the risks associated with fully reprogramming cells into stem cells.
[Gill, D., Parry, A., Santos, F., Okkenhaug, H., Seale, M., Dobbs, L. J., Reik, W., & Ocampo, A. (2022). Multi-omic rejuvenation of human cells by maturation phase transient reprogramming. eLife, 11, e71624. DOI: 10.7554/eLife.71624]
Just returned from my first trip to China, mostly looking at the energy and robotics industries. Fascinating. Random observations, both business and general, below...
1/x
When those who read and do research say that US Foreign Intelligence has its fingerprints all over Nigeria, those who don't need to learn how to shut up long enough to listen and maybe learn something.
Because you're being socially engineered like mice.
A thread.
Hi David, this is a very informative thread. Thank you.
In South Africa its CABC based in Cape Town. They publish their social media attacks and cyberbullying via Daily Maverick.
Can you check the one in London?. They did articles targeting people calling them "Russian agents". This is how people are charged, unlawfully arrested even killed. It's a big global funded network. The aim is to censor voices around the world.
You can learn a lot from mother nature when trading:
Bears hibernate when conditions get bad (don't overtrade)
Birds migrate to better conditions when the weather changes (pivot to hotter markets)
Squirrels stash nuts so they have food during slow seasons (save capital)
Here you are:-
Over 650,000 children in Denmark, followed for more than a decade
No increased risk of autism after MMR vaccination - even among kids with higher genetic risk.
Large sample, rigorous controls, registry-based data (not self-reported).
The study definitively found no link between the MMR vaccine and autism.
Vaccines do not cause autism.
Hviid et al., 2019 — Annals of Internal Medicine.
Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study.
Link: https://t.co/OYjj3k2Ik1
"from 1995 to 2022 its content in the average cannabis plant increased by 307 percent...compared with nonusers, cannabis users faced an 11-fold increase in the risk of developing a psychotic disorder." https://t.co/OWNf1Y5jNN
$TAO is an anchor of my #Altcoin portfolio.
I think that, once it cracks $280, we'll start to see a massive move towards $480.
It's the first mover and I think it will be a strong mover.
If we get to $480 without the other altcoins moving around, yes, I'll be rebalancing the portfolio.
Nigerian artist and animator, Nissi Ogulu, sister of Grammy-winning artist Burna Boy, has announced her latest project, 'SOPO'.
This animated film, produced through her company Creele Studios, draws inspiration from the early life of Afrobeat pioneer, Fela Kuti.
May 2025!
Instagram needs to be banned more urgently than pornhub for the betterment of society. I think it literally gives women mental illness via social contagion which rips apart families, gives them body dysmorphia so they get weird cosmetic mutilations, advertises materialism so they go into massive credit card debt trying to keep up with it, they prostitute their children for attention, convince eachother to divorce their husbands for not acting like castrated slaves to them, and gives them zero consequences for absolutely delusional political opinions. I know there’s some good stuff on ig and some good people, before you come at me with “it’s your algorithm girlie” shut up. You know full well how it affects the AVERAGE girl and I guarantee most of the brain rot from society would end if Meta burned down in a holy fire and Mark Zuckerberg was stocking grocery shelves the rest of his life to feed his wasian brood.
Tariffs are not the story!
Since Trump took office in Jan 2025, the 10-year yield has dropped from 4.79% to 4.17%. Look how much it’s dropped today!
That 0.62% drop may not sound like much—until you realize the U.S. has $36.5 trillion in debt.
This is stealth refinancing on a historic scale.
Lower yields = trillions in interest savings.
More breathing room. Less inflationary pressure.
And the market is front-running it.
Everyone’s watching tariffs.
But this yield curve shift?
It’s the real game.
Trump isn’t just cutting spending—
he’s restructuring America’s balance sheet in real time.