Domen Kampjut

Protein and metabolism enthusiast, drug discovery

[Domen Kampjut @DKampjut]

The unique and elegant mechanism of transhydrogenase involves a 180-degree rotation of the entire NADP(H) binding domain, alternately participating in hydride transfer and proton channel gating.

[Sazanov Lab @SazanovL]

(1) In our new Nature paper a universal 'domino effect' mechanism of complex I is proposed. Our previous version developed for mammalian complex is now elaborated by studies in E.coli. Mechanism is now much more detailed but robust. A thread.
https://t.co/h0AhHQyLkA

[Domen Kampjut @DKampjut]

Absolutely thrilled to see this paper published! Huge congratulations to @VO_Kravchuk, @SazanovL and others! This work all but fully validates the enzymatic mechanism that we proposed almost two years ago and should provide clarity and new direction for the field going forward

[ISTAustria @ISTAustria]

New Paper Alert: In @Nature published online, @SazanovL at @ISTAustria propose a universal mechanism of cellular respiration, culminating scientific work of ~20 years, starting from the structure of complex I to the domino effect of proton movement reported in today's paper. A🧵

[Martin Bauer @martinmbauer]

Postgraduate students in the UK now earn *less* then minimum wage!

This is already an emergency not even taking into acount the impact of soaring inflation and rising energy prices.

We need urgent action!
@UKRI_News @GeorgeFreemanMP @beisgovuk

1/7

[Simon Clark @simonoxfphys]

Did you know that a UK PhD stipend is so little that it puts recipients below the absolute poverty line?

UK PhD stipend (outside London): £16,062
Absolute poverty line (60% of 2011 median income): £16,883

No one does research for the money but surely we can do better than this?

[Sazanov Lab @SazanovL]

Structure of respiratory complex I – An emerging blueprint for the mec... https://t.co/Aty5EnHGrW

[ISTAustria @ISTAustria]

Scientists from 79 countries work at our Institute, among them many from Ukraine and Russia. In reaction to the war in Ukraine, we open a special internship program for students from Ukraine: https://t.co/YUkPQIH08Y

#Ukraine #freedom #nowarinukraine #NoWar #ukrainianscientists

[Domen Kampjut @DKampjut]

"Some star academics reached their position because they are bullies, not in spite of it."
"Hypecompetition, precarious employment and steep hierarchy [...] appear to incentivize bullies by providing conditions that allow them to thrive."

[Domen Kampjut @DKampjut]

This could not have been said better

[Andreas De Block @DeblockBlock]

These critiques are often dismissed by arguing that there are no alternatives. Yet, there are alternatives. For instance, lotteries would be better for most types of research.
https://t.co/tteaGnHKD4 And, there is even enough money in research for baseline funding. (16/16)

[Andreas De Block @DeblockBlock]

Gross and @CT_Bergstrom's mathematical model indicates that the costs of peer review and non-granted project applications are often higher than the total budget of a call. (7/16)
https://t.co/hmWWJeLutc

[Andreas De Block @DeblockBlock]

Most of these applications are unsuccessful. This is an enormous waste of money. For an Australian call, 500 years of research time (= €41 million in salaries) went into the applications for a call with a total value of €226 million. (5/16) https://t.co/q5JG3IP9Hm

[Andreas De Block @DeblockBlock]

Stop funding research
(the way you do)
Because it is wasteful, unethical and unscientific
A thread (1/16)

[Domen Kampjut @DKampjut]

Congratulations to my colleague Roz for this beautiful paper on Nf1 out in Nature today https://t.co/geckf90wja

[Frank Kelly @FrankFpk1]

Are you a researcher with PhD Degree awarded after 1st January 2020 and post-doctoral funding support at Cambridge University for at least two years? Want to be a fellow of @christs_college ? Apply here - https://t.co/ONurIjPPAi
@CamPostdocs

[Domen Kampjut @DKampjut]

"Policymakers were creating “cynical citizens with little trust in one another” by acting without regard for people’s ability to think for themselves"
https://t.co/Ro0OxvIwSY

[Domen Kampjut @DKampjut]

Mixed feelings about this - supervisors should be paid more but giving supervisions should not become a full time job - the idea is that students learn from people who are active researchers not professional supervisors https://t.co/r14FBaIWbf

[Domen Kampjut @DKampjut]

@irene50387182 @SazanovL @Nature Congratulations!!! Great story and beautiful structures

[IreVerce @vercellino_ire]

Our latest @SazanovL paper, revealing the structures and assembly mechanism of mammalian supercomplex CIII2CIV is out in @Nature
https://t.co/awyegisyMN

[Tanentzapf Lab @TanentzapfLab]

Imagine explaining to a layperson that 30-60% of scientist's time is spent on a thing that has upwards of 90% chance of failing & does not directly result in any advances to science or society. They would think we lost our minds. That "thing" exists & is grant writing & reviewing

[Domen Kampjut @DKampjut]

I am honoured to receive the Life Science Research Award Austria 2021 by the @LifeYlsa for my work on the coupling mechanism of complex I 🥳🎉 https://t.co/ygil1JLjzH