Dmitry Shcherbo

✴️ Oncology and liquid biopsy research ✴️

[Dmitry Shcherbo @DShcherbo]

Join our 🧬 #LiquidBiopsy team at Queen Mary University of London’s Blizard Institute as a 🔬 Research Technician. Develop cutting-edge pipelines to extract genetic and epigenetic information from #cfDNA and RNA.
🗓️ Deadline: 24th July
✅ Apply: https://t.co/oZVM63TRDZ

[Teif Lab @TeifLab]

We will soon have an opening for a three-year postdoc with expertise in machine learning and bioinformatics analysis of sequencing data to work on our liquid biopsy projects. Please get in touch by email or DM if interested.

[Dmitry Shcherbo @DShcherbo]

Wonderful @CNAPS2024 meeting in Graz was a great pleasure and a source of inspiration from #cfDNA community. As my first #CNAPS, it was a chance to see the people behind the papers. Many thanks to the organisers and all the attendees who made it possible.

[bioRxiv Bioinfo @biorxiv_bioinfo]

MethylBERT: A Transformer-based model for read-level DNA methylation pattern identification and tumour deconvolution https://t.co/8cPcKhkks5 #biorxiv_bioinfo

[Jamie Blundell @jrblundell]

James doing fascinating work on using immune signals for cancer detection - do come along for you can!

[Dmitry Shcherbo @DShcherbo]

An editor's view on using LLMs like ChatGPT for writing papers
#ISMBECCB2023

[Dmitry Shcherbo @DShcherbo]

DNA methylation atlas of normal human tissues. Impressive work by Prof. Tommy Kaplan and his team shared recently at @CRUK_CI will advance epigenetic-based #liquidbiopsy
More in their recent paper https://t.co/IqJpDfHl0p

[Florent Mouliere @FlorentMouliere]

Interested in cell-free DNA and #liquidbiopsy? Want a ride to catch up on the recent progress related to the biology of #cfDNA? Ask for hitchhiking!
Here is our new review: A hitchhiker’s guide to cell-free DNA biology https://t.co/hzwsSVCJyP

[Stephen Turner 🦋 @stephenturner.us @strnr]

ggmsa: multiple sequence alignment with ggplot2!
Paper: https://t.co/L09rwZmjNI
Src: https://t.co/EpvlhXRm0N
#Rstats 📦 https://t.co/L2Hp3C6PQX

[Dmitry Shcherbo @DShcherbo]

@TeifLab @CR_UK Glad to hear! Sounds like more opportunities for our colab 😁

[Dmitry Shcherbo @DShcherbo]

We thank all the donors for participation and RSCF @rnfpage for funding our research 🧵4/4

[Dmitry Shcherbo @DShcherbo]

Our paper on #cfDNA fragment end profiling in cancer is out. We focused on capturing shifts in end coordinates and sequence motifs in cancer-specific open-chromatin regions (OCRs) 🧵1/4 https://t.co/TCeq7x9aCd

[Dmitry Shcherbo @DShcherbo]

Based on the retrieved data we built a classifier to discriminate cancer (CRC and RCC) vs healthy in a cohort of 170 #liquidbiopsy samples. AUCs reached 0.9 🧵3/4

[Dmitry Shcherbo @DShcherbo]

@AlexandrePCheng @PNASNews Congratulations! I'm eager to read the paper.

[Dmitry Shcherbo @DShcherbo]

So happy that our brief review was noticed by the community 🥳

[Frontiers - Oncology @FrontOncology]

🧬 2021 Top #CancerGenetics Articles 🧬

#4: The Detection of Cancer Epigenetic Traces in Cell-Free DNA

👩‍⚕️👨‍⚕️ Anastasia P. Koval, Konstantin A. Blagodatskikh et al.

Read now 👉 https://t.co/OE3KMOq1Qt

@DShcherbo #Cancer #Oncology #Genetics

[Dmitry Shcherbo @DShcherbo]

@TeifLab @EssexLifeSci Great! Looking forward to resume our project :)

[Dmitry Shcherbo @DShcherbo]

@ATJCagan @MatLupien Exciting! I'm eager to read the paper, and the tweetorial is a masterpiece. By the way, why not include elephants or whales, just to stick with the classics? Any constraints on genomics or sample collecting?