🚨 Job Alert! Please RT 🙏
@ERC_Research-funded postdoc position in our team (up to 3 years) to explore dosage compensation during mouse development 🧬🐭 Join a dynamic, collaborative community @CbiToulouse!
👉 See how to apply here: https://t.co/h3u05G6wgs
Happy to share two post-doc papers co-authored with the amazing @AnaMonteagudo4 and @teresa_urli. We had amazing collaborators for both projects, even our supervisor @maxvcg joined in on the experimenting!
1: https://t.co/b3cr82wqJz
2: https://t.co/yvdaJWmY13
What does the RNA binding surface of PRC2 actually do?
We show that part of the RNA binding surface is required for PRC2 function through interactions with nucleosomes, but we find no evidence that RNA is in play.
https://t.co/rvNSI7txR6
Glad to announce the publication in @NatureComms of our study https://t.co/HrsjszBpkk by Pierre Romero & Laia Richart in Raphaël Margueron’s lab at @institut_curie on the molecular consequences of EZH2 mutations found in non-Hodgkin lymphoma. (1/3)
We combine a powerful isogenic cell culture model with a first-of-its-kind ChIP-seq analysis of follicular lymphoma samples from a unique longitudinal patient cohort to understand the mechanistic impact of EZH2 gain-of-function mutants on chromatin and transcription. (2/3)
Happy to share our review https://t.co/mJcOOoYT2U
we highlight the similarities and differences between ciliates and other eukaryotes in small-RNA-directed chromatin silencing.
@IJMonod@CNRSbiologie @toma_bln @DannyHoloch
🚨New Preprint🚨 In this study, we set out to determine how the de novo DNA methylation program impacts the 3D cis regulatory landscape. Comments welcome! Here's a thread detailing our study's key findings (1/12) https://t.co/UHElRVJTzC
@AdrianoAguzzi @baheesters Indeed. The second alternative is clearer. The first three words together function as a single adjective to describe what kind of receptor we are talking about.
Preprint alert. We’re thrilled to announce the latest work from our lab: The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium. A thread with our key findings: (1/6) https://t.co/4894dYRwfa
🚨Preprint Alert🚨 I am very proud to present our latest work, describing how DNA methylation shapes the polycomb landscape. A team effort, led by @jrichardalbert, @teresa_urli, and @AnaMonteagudo4 in the lab. Here's a 🧵 highlighting 🗝️ findings (1/12) https://t.co/JnDc4k02MO
Very glad to share our preprint: Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium https://t.co/5IpF2fBIf0. Feedback and comments are welcome !