Danny Holoch

[Danny Holoch @DannyHoloch]

Pleased to announce the publication in @NatureGenet of our work with Michel Wassef, Raphaël Margueron and others! https://t.co/21cgpEFzzq (1/2)

[Rafael Galupa @rafaelgalupa]

🚨 Job Alert! Please RT 🙏

@ERC_Research-funded postdoc position in our team (up to 3 years) to explore dosage compensation during mouse development 🧬🐭 Join a dynamic, collaborative community @CbiToulouse!

👉 See how to apply here: https://t.co/h3u05G6wgs

[Julien Richard Albert @jrichardalbert]

Happy to share two post-doc papers co-authored with the amazing @AnaMonteagudo4 and @teresa_urli. We had amazing collaborators for both projects, even our supervisor @maxvcg joined in on the experimenting!
1: https://t.co/b3cr82wqJz
2: https://t.co/yvdaJWmY13

[Maxim Greenberg @maxvcg]

Usually, I just trash these spam conference invites. But it's not every day I get an email from one of my scientific heroes.

[Chen Davidovich @DavidovichLab]

What does the RNA binding surface of PRC2 actually do?

We show that part of the RNA binding surface is required for PRC2 function through interactions with nucleosomes, but we find no evidence that RNA is in play.

https://t.co/rvNSI7txR6

[lw @waltzer_lucas]

Very glad to share our latest publication on TET mode of action !
#drosophila #epigenetics

https://t.co/nSHOsISDgf

[National Academy of Sciences @theNASciences]

Congratulations Danesh Moazed of @harvardmed, newly inducted #NASmember! #NAS161 #genetics #cellbiology

[Danny Holoch @DannyHoloch]

We are immensely grateful for this collaboration with @AVincentSalomon and for funding support from @institut_curie, @Inserm, @CNRS, @FondationARC, @FRM_officiel, @Fondationfrance, @AgenceRecherche and @canceropole. (3/3)

[Danny Holoch @DannyHoloch]

Glad to announce the publication in @NatureComms of our study https://t.co/HrsjszBpkk by Pierre Romero & Laia Richart in Raphaël Margueron’s lab at @institut_curie on the molecular consequences of EZH2 mutations found in non-Hodgkin lymphoma. (1/3)

[Danny Holoch @DannyHoloch]

We combine a powerful isogenic cell culture model with a first-of-its-kind ChIP-seq analysis of follicular lymphoma samples from a unique longitudinal patient cohort to understand the mechanistic impact of EZH2 gain-of-function mutants on chromatin and transcription. (2/3)

[Danny Holoch @DannyHoloch]

@toma_bln Congratulations Thomas!

[DuharcourtLab @DuharcourtLab]

Happy to share our review https://t.co/mJcOOoYT2U
we highlight the similarities and differences between ciliates and other eukaryotes in small-RNA-directed chromatin silencing.
@IJMonod @CNRSbiologie @toma_bln @DannyHoloch

[Danny Holoch @DannyHoloch]

@maxvcg Looks like really beautiful work. Looking forward to reading this!

[Maxim Greenberg @maxvcg]

🚨New Preprint🚨 In this study, we set out to determine how the de novo DNA methylation program impacts the 3D cis regulatory landscape. Comments welcome! Here's a thread detailing our study's key findings (1/12) https://t.co/UHElRVJTzC

[Danny Holoch @DannyHoloch]

@AdrianoAguzzi @baheesters 🤣 https://t.co/msnFGgEuGt.

[Danny Holoch @DannyHoloch]

@AdrianoAguzzi @baheesters Indeed. The second alternative is clearer. The first three words together function as a single adjective to describe what kind of receptor we are talking about.

[DuharcourtLab @DuharcourtLab]

Preprint alert. We’re thrilled to announce the latest work from our lab: The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium. A thread with our key findings: (1/6) https://t.co/4894dYRwfa

[Julien Richard Albert @jrichardalbert]

DNA methylation can antagonize Polycomb-mediated gene silencing - neat!
https://t.co/46aSKzHZxI

[Maxim Greenberg @maxvcg]

🚨Preprint Alert🚨 I am very proud to present our latest work, describing how DNA methylation shapes the polycomb landscape. A team effort, led by @jrichardalbert, @teresa_urli, and @AnaMonteagudo4 in the lab. Here's a 🧵 highlighting 🗝️ findings (1/12) https://t.co/JnDc4k02MO

[DuharcourtLab @DuharcourtLab]

Very glad to share our preprint: Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium https://t.co/5IpF2fBIf0. Feedback and comments are welcome !

[DuharcourtLab @DuharcourtLab]

Very honored to be part of the @EMBO community. Thanks to past and present lab members, and collaborators, and to @IJMonod for a great environment.