Daryl Gohl

Group Leader, University of Minnesota Genomics Center Innovation Lab. Founder, CoreBiome (now Diversigen).

[NIH ORIP @NIH_ORIP]

READ: “High-throughput genetic manipulation of multicellular organisms using a machine-vision guided embryonic microinjection robot.” Alegria et al. @NSF (ORIP support through 1R21OD028214, 1R24OD028444)
https://t.co/mU8gNruU6Y

[Suhasa @bksuhasa]

New paper in our lab led by Andrew Alegria and @Amey__Joshi published in @GeneticsGSA . Fun collab with @DarylGohl and Bischof group @umnme @UMNCSE We also made it to the cover! https://t.co/lpyiQNmj4a

[Genetics Society of America @GeneticsGSA]

On the cover of the April issue of GENETICS: An automated microinjection of Drosophila embryos by a computer vision-guided robot. Alegria et al. present a machine vision guided generalized robot that automates the process of microinjection in fruit fly and zebrafish embryos.
🧵⬇️

[Suhasa @bksuhasa]

🚨 New pre-print alert!🚨 Led by the brilliant, twitter-less post-doc James Hope. We built a 🤖 exoskeleton for 🐭🐁 so we can study their 🧠's as they go around navigating their world. An e.g., imaging 1000s of neurons in the cortex when mice walk an 8-maze. A 🧵

[Amey Joshi @Amey__Joshi]

I am really excited to share that our new pre-print on “A machine vision guided robot for fully automated embryonic microinjection” is out. Thanks to @AndrewAlegria37, all collaborators and @bksuhasa @DarylGohl

[Daryl Gohl @DarylGohl]

This work was led by two amazing grad students, @Amey__Joshi and @AndrewAlegria37, with critical contributions from @sciberius and Jorge Blanco Mendana (not on Twitter). Many thanks to all our co-authors! (10/10)

[Daryl Gohl @DarylGohl]

Really excited to share this new preprint on automated microinjection of Drosophila and zebrafish embryos! See this thread by our collaborator @bksuhasa

[Suhasa @bksuhasa]

🚨🚨 New pre-print alert! A fun collaboration involving 🤖s, fruit🪰s,🐠, and 🧬 with @DarylGohl. Co-led by twitterless Andrew Alegria and @Amey__Joshi . A generalized machine vision guided robot for microinjections into whole intact embryos. https://t.co/Xgef3BcImn (1/n)

[Daryl Gohl @DarylGohl]

We also trained a separate machine learning model and used the same robot to successfully inject zebrafish embryos and believe that this robotic system can be readily generalized to carry out automated microinjection in many other species. (9/10)

[Itai Yanai @ItaiYanai]

New paper! It’s absolutely wild what you see when studying bacteria using single-cell RNA-Seq! Unlike in eukaryotes, we found a genome-scale pattern of correlations among genes showing a strong dependency on global chromosomal locations.
https://t.co/Rlj5s1NN6f @AndrewPountain

[Josie Kishi @jykishi]

What if you could image 🔬cells and then choose which ones to sequence 🧬?

What if you could go back and image 🔬cells that you previously sequenced 🧬?

Now you can 🔬 then 🧬 then 🔬 cells again with Light-Seq!

https://t.co/ZuDIOfnqyj

Let’s dig in 🧵.

[Xiaojing Gao @SynBioGaoLab]

Our ADAR-based RNA sensors just came online! https://t.co/XSOXU8lzSR It allows you to express protein payloads in live cells in direct response to the presence of specific RNA transcripts. Also @EerikKaseniit, welcome to twitter.

[Daryl Gohl @DarylGohl]

@yvetteefisher @NIH_CommonFund Amazing news! Congrats!