Ben Levy

Scientific ML. Senior Data Scientist @physicsx. He/Him. 🇨🇦🇺🇸

[Nadav Brandes @BrandesNadav]

Really cool work! Initial thoughts:

1. The performance leap compared to Evo2, GPN-MSA etc. is quite remarkable, but we need to remember it's a supervised approach. The gene-level split sounds reasonable, but information leakage is notoriously difficult to eliminate in supervised variant effect prediction. It remains to be seen how well it generalizes (I hope to see more comprehensive evals in the peer-reviewed version).

2. I'm a bit skeptical about the LLM-generated reports reflecting either the true disease mechanism of the variants or the true reasoning behind the Evo2 probe predictions.

3. At the same time, I will not be surprised if geneticists end up liking and using these reports, even if they are not entirely faithful. At least they attempt to provide an explanation (unlike virtually all other variant effect prediction tools), so it's an important step in a neglected direction.

4. Moreover, I'd argue that a lot of biological and clinical reasoning is already in the realm of nice-sounding storytelling and half truths, so we also need to be honest about what human-level biological interpretation is when we judge whether AI is making things better or worse.

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Ben Levy @Datacrafting1]

@ChelseaParlett “Gamma”
“Mmm that’s a nice woody distribution”

[Ben Levy @Datacrafting1]

News people: Ah January 6, the darkest day in recent American history. Nothing good ever happened on this cursed day.

People born on Jan 6: 🥺👉👈

[Ben Levy @Datacrafting1]

@LebVeronique @nytimes long time player first time commenter huge opportunity here if you ask me 🤓

[Gary Marcus @GaryMarcus]

There are two kinds of people who don’t like mob rule

1. those who genuinely don’t like mob rule
and
2. and those just want to rule a different mob

You can’t legitimately battle antisemitism from Tower 2.

[Ben Levy @Datacrafting1]

@ChelseaParlett Maybe you can resolve this using Turkey's Honestly Significant Difference test

[Jonathan Rosenthal @rosenthal_jon]

I have been struggling to articulate the complex emotions I've been feeling since Saturday morning as a Jew, a liberal/progressive, a believer that Palestinians and Jews have a right to a homeland, to safety and dignity. A thread 1/

[Ben Levy @Datacrafting1]

@moleculargf Why would you put Prosecco in pasta

[Ben Levy @Datacrafting1]

@moleculargf What’s a Negroni spaghetti

[Ben Levy @Datacrafting1]

@GNolanMEd Now I just need a dog-specific one: https://t.co/2TO6Rbdsw0???

[Ben Levy @Datacrafting1]

I'm excited to announce the launch of https://t.co/j0IVGgrX6o! An AI-powered tool to help determine whether a food is safe for your dog to eat 🐶🍔.

🧵

[Ben Levy @Datacrafting1]

...In all seriousness though, this project was a lot of fun to create and I got to learn about creating a full-stack web app leveraging GenAI. Feel free to dm me if you're curious about how I built it!

/Fin

[Ben Levy @Datacrafting1]

Powered by OpenAI, we use the most cutting-edge AI technology to solve this age-old problem. Give it a try! And let me know if you have any feedback that could make the experience better.

[Peter Hull @instrumenthull]

Eh. If you've heard it once, you've heard it a thousand times

[Sesame Street @sesamestreet]

The letter X will be holding a press conference later today. #TwitterX

[David Frum @davidfrum]

Antisemitism is at bottom a conspiracy theory. It offers a story about a tiny, malign group who mastermind all world events, from the killing of Jesus to the creation of both capitalism and communism. People who start down the path of any kind of conspiracy-seeking ...

[Military History Now @MilHistNow]

On this day in 1939, a German passenger liner carrying more than 900 Jewish refugees from the Third Reich is turned away from a U.S. port. The vessel, known as the St. Louis, is forced to return to Europe where many of those on board will be murdered by the Nazis.