Luvy Delfin

PGY-3 AP/CP resident @CWRU University Hospitals. Future Head&Neck Pathology fellow @UTSW2023. #Endopath#Cytopath😍

[C. Christofer Juhlin @DrJuhlin]

Parathyroid tumors are highly heterogenous in terms of cellular composition and growth patterns - so what happens if you put a fine needle in one?

[North American Society of Head & Neck Pathology @NASHNPath]

Happy Friday everybody!
Here's a holiday treat shared by @dannyjlubinpath.

Middle aged pt with a sinonasal mass.
What ancillary testing might you pursue to arrive at the correct diagnosis?

[C. Christofer Juhlin @DrJuhlin]

50 y/o HIV positive man with a 46 mm anal lesion. Routine H&E of the proctectomy. The squamous epithelium (lower right) is severely dysplastic, and a transition to an invasive SCC is noted.

[Ilan Weinreb 🇮🇱🇨🇦 אילן וינרב @WeinrebIlan]

Multifocal oncocytoma/oncocytosis of parotid.

🔹multiple nodules, some circumscribed and some not.

🔹some can be clear cell rich.

🔹p63 should show an incomplete outer layer around the nests.

But wait…aren’t these supposed to be golden brown grossly? See final pic.

[Head Neck Pathol @HeadNeckPathol]

Whole Exome Sequencing Identifies Somatic Variants in an Oral Composite Hemangioendothelioma Characterized by YAP1::MAML2 Fusion
Koutlas, Oetting, Burns, Gopalakrishnan & Antonescu
https://t.co/JqWBp07uLt
#HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet

[C. Christofer Juhlin @DrJuhlin]

Fear the TERT! 😂 Follicular thyroid carcinomas with TERT promoter mutations exhibit a unique global micro-RNA landscape compared to wildtype cases, including miRs that could explain why TERT promoter mutations confer aggressive tumor biology. Read our latest work in @EndoPath!

[C. Christofer Juhlin @DrJuhlin]

8 y/o boy with Cushing's syndrome. Previous lateralization to the left adrenal, displaying "cortical hyperplasia" on histology. Now recurrent hypercortisolism, right-sided adrenalectomy is performed. An irregular cortex with numerous nodules is evident.

[Ilan Weinreb 🇮🇱🇨🇦 אילן וינרב @WeinrebIlan]

Another Warthin tumour with a stowaway…

Since it came up in my previous tweet last week…

Here is an actual acinic cell carcinoma inside a Warthin tumour!

[Syed Z. Ali @sza_jhcyto]

Almost a pure culture of malignant cells in this pleural fluid - Metastatic "Cholangiocarcinoma".

[Luvy Delfin @DelfinLuvy]

@DrJuhlin Stunning! 🤩

[C. Christofer Juhlin @DrJuhlin]

83-y/o female patient with a 30 mm thyroid nodule, FNAC consistent with Bethesda IV. Left-sided lobectomy is performed. A well-demarcated tumor with a defined capsule is seen.

[Tristan Rutland MBBS FRCPA IFCAP @TristanRutland7]

Wrist lump, older female.

#Dermpath #BSTpath #Pathtwitter #Pathresidents

[Jeffrey Cloutier, MD, PhD @JCloutierMD]

A rare sarcoma worthy of sharing.

Sclerosing epithelioid fibrosarcoma.

MUC4 IHC shown.

First described by my mentor Dr. Meis in 1995. Her more recent study of 51 cases emphasizes its potential for aggressive behavior ➡️ https://t.co/LK9fkUR0Ex

#BSTpath #sarcoma

[Luvy Delfin @DelfinLuvy]

@DrJuhlin @CryRonchi @IrinaBancos @sarapakbaz21 @SarahJJohnson8 @daniel_berney @HENRYY_MD @YalePathRes Thanks for tagging me! Always great cases and even better presentation 🤩

[Elizabeth Montgomery, MD @LizMontgomeryMD]

This is an example of an epithelioid sarcoma that spread to the lung. Curiously, it has retained it's granuloma-like appearance.

[Bin Xu @BinXu16]

An interesting #ENTpath #oralpath case. a 1 cm lesion at the Stensens duct.

[Luvy Delfin @DelfinLuvy]

@UTSW_Pathology a

[Luvy Delfin @DelfinLuvy]

@UTSW_Pathology a

[Luvy Delfin @DelfinLuvy]

Amazing learning points!🤩

[C. Christofer Juhlin @DrJuhlin]

70-y-o male, 70 mm adrenal mass. Tumor necrosis, pleomorphism and capsular invasion is seen.