Dimitris Typas

Senior Editor @NatureSMB. Views and opinions are personal.

[Jakob Nilsson @NilssonLabCph]

Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. https://t.co/FL9JsNhOuK

[Cris Mayor-Ruiz @CrisMayorRuiz]

🔥 Chem(bio) friends, this one is big!!
IRB Barcelona is opening a Group Leader position in Chemical Biology! 💜

If your research plan and vision are at the interface of synthetic chemistry, chemical biology, and biomedicine, please check the call!

👉https://t.co/isTnrxMYjl

[Dimitris Typas @DimitrisTypas]

A well-worth-your-time Comment by Dr. Edith Heard, of
@TheCrick, and Dr. Gitte Neubauer, one of the founders of Cellzome, now at GSK, is out @NatureSMB . They provide valuable insight into what makes a successful partnership between academia and industry.
https://t.co/PJO5RPL4hs

[Dimitris Typas @DimitrisTypas]

Tempted to add (more) METAL gifs, but we @NatureSMB are indeed glad to feature METALoci and the conceptual advance imparted by the study in our pages.

[Irene Mota @IreneMota]

How is sex determined? How is it encoded in the #3Dgenome?
Happy to share my PhD work. Sex-determining 3D regulatory hubs identified w METALoci, a new genome spatial auto-correlation approach

With @jrotwitguez Capel Lab @mamartirenom @Dariloops

Thread 👇https://t.co/GIjsYuzpwC

[Dimitris Typas @DimitrisTypas]

Late to the party, but I wanted to highlight a recent @NatureSMB paper by the Hajkova and Vaquerizas labs, which notably advances our understanding of how chromatin organisation regulates gametogenesis. Very enjoyable and insightful work!
https://t.co/Cv2HZjdmNx

[Dimitris Typas @DimitrisTypas]

Mitosis is not a chromatin barren landscape after all. A very insightful study @NatureSMB by the lab of @Anders_S_Hansen tells an intriguing story https://t.co/yHZcZRBKTz. @MITdeptofBE has put together a nice summary too https://t.co/CNhAzSH2c0

[Dimitris Typas @DimitrisTypas]

Our September @NatureSMB issue is out! https://t.co/gFczbKrByD We feature very interesting papers on ubiquitylation and degradation. Really excited to continue to serve the proteostasis and PTMs communities and publish conceptually insightful work.

[Gabriele Zaffagnini @zaffagg3]

Great to see our work featured in @NatureSMB! Thanks @DimitrisTypas for your coverage! @LabBoke @DexeusMujer

[Dimitris Typas @DimitrisTypas]

A captivating read on a very interesting topic, the closer-than-anticipated relationship between ubiquitin and ADP-ribose just out @NatureSMB, https://t.co/mNf41Z98EB

[Rockefeller University @RockefellerUniv]

In this Q&A with @NatureSMB, @RiceLaboratory and Yael David of @MSKCancerCenter comment on new work that advances the molecular understanding of and, potentially, the clinical arsenal against infection with Hepatitis B virus. #WorldHepatitisDay
https://t.co/jBqPMexWGT

[NatureStructMolBiol @NatureSMB]

New online! Q&A with Yael David and Charles Rice on using chromatin biology to understand hepatitis https://t.co/1qiLZuZcyQ

[BökeLab @LabBoke]

Proud to share what we hope will be a reference study on human oocyte proteostasis. Young-donor eggs show globally reduced organelle activity vs. somatic cells, with an even steeper drop as they mature.
👇 for @zaffagg3 's detailed explanation

https://t.co/NQ1krrsRYb

[Dimitris Typas @DimitrisTypas]

On vacation, but so happy this is out and very proud to have had this discussion. I hope that the @NatureSMB readers appreciate it.

[Yael David @Yael_David__]

And to top it all off, @DimitrisTypas @NatureSMB published today a fantastic Q&A with Charlie @RiceLaboratory @RockefellerUniv, and me discussing our recent Hepatitis B chromatin paper in @CellCellPress! Such an honor to share this space. 🙏🏻 @NobelPrize

https://t.co/4GZQ9Rk5wk

[Dimitris Typas @DimitrisTypas]

Insightful work with potential against henipaviruses out @NatureSMB; have a nice read if interested, https://t.co/OQ39s8CWHb

[Suyang Zhang @Zhang_Suyang]

A transcription balance required for genome stability 🧬⚖️

Our work on RNA Pol II transcription speed control by the DNA helicase RECQL5 and the transcription-coupled DNA repair complex is now on ⁦⁦@NatureSMB⁩

#CryoEM #transcription https://t.co/BXgtzSF10A

[Dimitris Typas @DimitrisTypas]

Scientists travel to work. Some continue to travel during their career, some set roots to an adopted country, some return. @NatureSMB will publish 5 pieces on those that returned. The first discusses Dr. Gomes Dias' return to Brazil. Touching+inspiring. https://t.co/9rag8YlIoU

[Dimitris Typas @DimitrisTypas]

Out @NatureSMB a Review on origin licensing with the most comprehensive (and coolest!) movies on how pre-RC assembly works. Decades of structural and biochemical work are beautifully illustrated. Kudos to @janetiwasa, John Diffley and Bruce Stillman. https://t.co/gXKX1R3QK3

[Dimitris Typas @DimitrisTypas]

On the way to #cshlubiq; the speakers and posters sound top-notch. If you have any questions about @NatureSMB or just want to chat science, please feel free to say hi.

[Dimitris Typas @DimitrisTypas]

A bit late to promote this excellent work reporting the development of BRISC molecular glues (BLUEs) https://t.co/rMrJaiAWjm. This paper is the first in a series of insightful ubiquitylation-related manuscripts with disease-related relevance @NatureSMB will publish

[Roger Greenberg @RogerRogergr]

Please see our discovery of first-in-class BRISC deubiquitylating enzyme inhibitors https://t.co/OXmr1CGra8. A great journey with Elton Zeqiraj, Francesca Chandler, Joe Salvino. High-throughput screens, cryo-EM structure and ontarget activity to reduce inflammatory signals.