🆕 Aspirina, todo lo que debes saber: Indicaciones, efectos adversos, interacciones, contraindicaciones y más.
📕 BMJ || Via @FarmaMadridAP
📁 Resumen del artículo en https://t.co/S5ipPCpFQT
Type 2 diabetes affects up to 14% of the global population.
This Review discusses the diagnosis, treatment, and prognosis of adults with type 2 diabetes.
#ADASCiSessions@ADA_DiabetesPro
https://t.co/na2jEmaefE
Heart failure with preserved ejection fraction therapeutics: in search of the pillars
transformative era in HFpEF management, with multiple landmark clinical trials demonstrating benefits for novel therapeutic classes : SGLT2i , Ns-MRAs, GLP-1a
https://t.co/uCWLY41OK1
Reevaluating Beta-Blocker Recommendations Post-Myocardial Infarction: Perspective on the 2025 Guideline Update: @JACCJournals
🥸Commentary on the guidelines - early beta blocker use post MI -
😱@MichaelGNanna wrote extensively on this in older pts.
🥸Take a look
👇👇👇
Pathogenic features of osteoarthritis (OA)
OA involves the entire joint organ👇🏼
>subchondral bone
>menisci
>ligaments
>periarticular muscle
>capsule
>synovium
These changes eventually 👉🏾”joint failure”
#osteoarthritis#joint
https://t.co/UYQJN1k22Q
This is why I write about science and health misinformation—because there's no end to grifters taking advantage of people (who are often rightfully frustrated with our for-profit healthcare system), and those people believe them.
And too often the victims are children.
Dear friends, my sincere request is that you do not follow health advice, especially from those who are not science-based healthcare providers or clinical medicine practitioners.
Sean here, is an entrepreneur in eCommerce, SaaS & B2B service categories. He has not seen the inside of a biology text book in school and has no clue about human anatomy, physiology, pharmacology, toxicology and clinical levels of evidence.
https://t.co/PCmIHzDLSu
Please do not consume herbal and dietary supplements in the belief that you will "age slower," or improve your "biological age," or "increase your VO2max," or "get your metabolic health comparable to your toddler," or "increase your sperm count to beat your stable horses," or "increase testosterone to make The Hulk look dumb." It is absurd.
Just be you. Nothing beats a balanced diet, daily physical activity (aerobics/weight training), avoiding alcohol and tobacco and embracing healthy work hours and adequate sleep. Do not forget to cater to your mental health in between all of this. It is also important.
Most of these posts, like Sean's here, are for engagement farming to promote a sales pitch. The supplements description section features a lot of brand names that he has endorsed for a possible commission. None of those supplements work. It is a fact. And many of those supplements can actually harm.
Please see (take your time) this exhaustive database from the US Government's National Institutes of Health, Office of Dietary Supplements for clarity on which supplements work and in conditions they are recommended and which supplements dont.
https://t.co/iXUouw0yLE
Herbal and dietary supplements are now now the biggest cause for increasing liver transplants in the USA, (no) thanks to sales pitchers like Sean and other tech bros who do it for the business of healthcare.
https://t.co/D4r8kqYhSf
And that is not all. Herbal and dietary supplements related liver injury is far more severe and serious than standard prescription drugs related liver injury. Meaning, the chances of dying or receiving a liver transplant is higher with supplements-related liver failure.
https://t.co/2pKSrlF0NS
Tech bros and other medically-illiterates use "science-sounding" jargons to confuse people into thinking they are "credible."
For example, Sean mentions that albumin level is a "function of the liver" - it is not. Albumin provides an idea of the biosynthetic function of the liver and not the whole liver function. The liver performs more than 500 vital functions - metabolic, synthetic, secretory, excretory, immunity, digestive and many more.
https://t.co/Hb2M0HUKsG
Alkaline phosphatase is also not actually liver function as Sean mentions. Alkaline phosphatase is present in the placenta, ileal mucosa, kidney, bone, and liver - and not only in the liver.
https://t.co/TXWTrqUaq0
Creatinine is also not realistically kidney function related. Serum creatinine is widely interpreted as a measure only of renal function; however, the serum level reflects not only renal excretion, but also the generation, intake, and metabolism of creatinine which are dependent on many other factors other than kidneys.
https://t.co/VqMzOovVcL
Glucose as a the singular marker of metabolism is utter nonsense, as Sean mentions and many blood parameters mentioned are an exaggeration of the claims made, such as immune system function (immune system has innate and adaptive components and a simple blood count tests does not provide any clear data on it)
https://t.co/AqW75yrTfS
Sean's post is a masterclass on both misinformation and disinformation. Misinformation is false or inaccurate information—getting the facts wrong. Disinformation is false information which is deliberately intended to mislead—intentionally misstating the facts.
Be wary of such handles and stay FAR away from them, for your own good.
Study findings do not support the treatment of elevated inpatient blood pressures in hospitalized older adults without evidence of end organ damage and highlight the need for randomized clinical trials of inpatient blood pressure treatment targets. https://t.co/wXQy3j8XcW
New “cognitive” #depression proposed with 1) Slow processing 2) Insomnia 3) Low functioning 4) Impairments in cognitive control circuits on fMRI. It had poorer response to antidepressants in this trial:
https://t.co/0n8sYJcI9y
They are exploring guanfacine & TMS -@ChrisAikenMD
Long-awaited Traverse Trial shows no difference in MACE between testosterone and placebo groups in 5246 men treated for mean 22 months. Reassuring, not surprising.
Indeed, the surprise is that CVD was ever raised as a concern! A thread.
If nothing changes, 1 in 2 of us will see our lives devastated by dementia. Either by caring for someone with the condition, developing it ourselves, or both.
This is why we exist. We're leading the search #ForACure 🟧
Find out more here: https://t.co/rVxVvA0WMV
The 2023 AGS Beers Criteria for Potentially Inappropriate Medication Use in Older Adults is out! Learn more about the criteria and how to use it. Guests Todd Semla & @MikeSteinman (both helped update the criteria).
Episode https://t.co/fUmNCcVoeO - hosts @AlexSmithMD | @EWidera