Don Sin

I am a respirologist and my main research interest is finding innovative new therapeutic solutions to patients with COPD. The postings reflect personal views

[Don Sin @donsin4]

Following the 7th World Symposium on #PH, this review summarises the current understanding of ILD-PH. What a beautiful review, even as a COPDologist, I appreciated its elegance. https://t.co/RAq993bOBa

[Don Sin @donsin4]

One way of getting away from the messiness of reference values is to use raw FEV1 data. Here, the authors have developed FEV1Q and other "Q"s, which may be better in predicting mortality in #COPD. https://t.co/4PW5dqbDKI

[Don Sin @donsin4]

Authors argue that use of a single “race-neutral” predictions can misinterpret inherent differences in lung health and that geographic ancestry should be considered in volume prediction equations for healthy individuals including FEV1. Do you agree? https://t.co/6XRZCh2v8u

[Don Sin @donsin4]

Long COVID Practice Guidelines on the prevention and treatment of long COVID. Finally, something that we can use at the bedside to manage our patients with long #COVID. Separating signal from noise... https://t.co/lEUd47Csod

[Don Sin @donsin4]

In the FIBRONEER-ILD trial in patients with progressive pulmonary fibrosis, nerandomilast reduced the risk of death and other outcomes in #PPF https://t.co/abWzdKxUza

[Don Sin @donsin4]

One of the motivations for #GOLD changing "E" to >=1 exacerbation/yr is the high risk of CV events during exacerbation. Here, authors have created CE-MACE model to predict 1-year MACE risk following a #COPD exacerbation. Check out the online calculator! https://t.co/O8YYTGJ71x

[Don Sin @donsin4]

Here, the GOLD committee clarifies 3 misunderstood concepts in the 2026 GOLD document. The most important is that anyone with one or more exacerbations are now in category "E". Huge change. Read all about it @ERSpublications https://t.co/4VmS4U1L2L

[James D Chalmers @ProfJDChalmers]

This months ERJ is an absolute blockbuster - check it out!
Clinical practice guideline for long COVID prevention and treatment - https://t.co/wUec4mYVaw

Pulmonary hypertension associated with interstitial lung disease: a state-of-the-art review- https://t.co/CCUa2aIB5O

Core outcome set for trials evaluating the management of community-acquired and nosocomial pneumonia in adults: an ERS statement- https://t.co/LIKOmlKCNA

Clarifying the GOLD 2026 guidance for initial pharmacological COPD treatment-https://t.co/7TLP75IG0b

Nerandomilast in progressive pulmonary fibrosis: data from the whole follow-up period of the FIBRONEER-ILD trial- https://t.co/owVIMnLoHq

https://t.co/6LmYLflxkc

[Don Sin @donsin4]

Good teeth, good brain!

[World of Statistics @stats_feed]

Dental flossing was significantly associated with a lower risk of ischemic stroke in a 2025 study.

[Don Sin @donsin4]

Absolutely heart-breaking story of how science gone astray led to a death of a young child. Meanwhile, the primary investigator of the technology is still publishing in top tier journals as if nothing ever happened.

[Science Magazine @ScienceMagazine]

Parents want accountability after a cutting-edge gene-editing trial in China went disastrously wrong, according to an exclusive investigation from Science and @RetractionWatch.

Learn more: https://t.co/L3a6iyy1zh @NewsfromScience

[Don Sin @donsin4]

@leah_pierson This is a rather narrow view of "being a doctor". Clinician-scientists are some of the best physicians in the world. Being a doctor is implementing exceptional science at the bedside with compassion and thoughtfulness. A doctor is more than just "seeing patients".

[Don Sin @donsin4]

"the results were simply too good to be true..." Another Nature paper retracted because of irregularities. Editors, if the data are too good to be true, they are likely NOT true!

[FiercePharma @FiercePharma]

Nature Medicine has pulled a controversial paper tying lung cancer survival to PD-1 treatment timing
https://t.co/JxAbOc6gI8

[Don Sin @donsin4]

#UBC no. 2 in #Canada among universities.

[CTV News @CTVNews]

3 Canadian universities crack global list of best 100, including 1 in the top 20 https://t.co/cDnTLlEfO5

[Don Sin @donsin4]

@PfParks This is true but what these data are leaving out is the cost of care. For example, physician compensation in Canada is >60% greater than that in Germany; same with other health professionals. The government has no money to build additional hospitals

[Don Sin @donsin4]

@raghu_venugopal @NightShiftMD yes, agree with fundamental changes to the health care system including the use of AI, but mindlessly increasing physician supply is neither transformative nor addressing the fundamental problems in our system. Just adding to costs.

[Don Sin @donsin4]

This is the graph when we include BC govt's annual increase in health care budget since 2000 on the same plot. How is this sustainable?

[Don Sin @donsin4]

#doctorsofbc published a survey indicating the increasing wait time of patients to see specialists in #BC. While there are many causes for this, just mindlessly increasing physician supply is NOT the answer. Since 2000, BC's pop has increased by 41% but no. of docs have doubled.

[Don Sin @donsin4]

#doctorsofbc published a survey indicating the increasing wait time of patients to see specialists in #BC. While there are many causes for this, just mindlessly increasing physician supply is NOT the answer. Since 2000, BC's pop has increased by 41% but no. of docs have doubled.

[Don Sin @donsin4]

@JackieBee_16 Does this include interpretation charges by radiologists or just the cost of the procedure?

[Don Sin @donsin4]

Large scale proteomics reveal new biomarkers and therapeutic targets in #COPD. What are these biomarkers? Many in the metabolic pathway. Why? Here Xuekui and I go into the reasons behind this observation https://t.co/e9YYsRqADy

[Don Sin @donsin4]

@DrSamuelBHume This curve mirrors the dramatic fall in the rates of smoking in U.S. and elsewhere