C19 Science

Biology and Epidemiology of #SARS-nCoV-2 #Covid-19. Selective content.

[Prof Peter Hotez MD PhD DSc(hon) @PeterHotez]

1/ In the news of late: what Covid mRNA vaccines can/cannot do in terms of preventing/halting severe illness vs symptomatic infection vs asymptomatic infection/transmission vs long Covid or other chronic sequelae. Will try and clarify things over the next day or so in this thread

[Dr. Gustavo Aguirre-Chang @Aguirre1Gustavo]

ASYMPTOMATIC OR LATENT PERSISTENT INFECTION IN CHILDREN.

SARS COV-2 WAS DETECTED IN BIOPSIES OF TONSILS OR ADENOIDS
IN 25% OF ASYMPTOMATIC CHILDREN
None had experienced signs or symptoms

Authors point out:
lymphoid tissue may be a Reservoir of SARS-CoV-2
https://t.co/kKh1cnq6y0

[T. Ryan Gregory 🇨🇦 @TRyanGregory]

Someone asked for a collection of my COVID threads in advance of (US) Thanksgiving in case they want to share some info with family members. Here you go (links to Twitter thread and Threadreader). 🧵

[C19 Science @DorianUpdate]

COVID-19 Origins: Investigating a “Complex and Grave Situation” Inside a Wuhan Lab — ProPublica https://t.co/jE5TBaxFVa

[Quantіan @quantian1]

If lab leak were true, we would know it beyond question now, because:
1. Chinese officials would have sent 2147483647 panicked emails and calls to each other in late 2019
2. The NSA would have intercepted them all
3. Trump would have tweeted out the transcripts sometime in 2020

[David Cox @neurobongo]

Looks like the "Prime and Spike" paper got peer reviewed and published (feels like the preprint came out ages ago). It looks amazing as a strategy. Is there any reason to have any optimism that this is going to be available any time soon and/or ever?

[C19 Science @DorianUpdate]

@jonginsf @quantian1 Haven’t heard of this theory. Please elaborate?

[C19 Science @DorianUpdate]

@arkabagchi24 @Adrian_H @MoralOverdraft Would add more speculation, but:

[C19 Science @DorianUpdate]

@arkabagchi24 @Adrian_H @MoralOverdraft More likely to provide credibility kitty so government agencies confidence post-settlement compliance will be respected, as in case of Alcon.

[C19 Science @DorianUpdate]

@Adrian_H @MoralOverdraft General Counsels are usually not primary litigators or agency negotiators. Rather, GCs help their employers increase efficiency, reduce cost, and improve effectiveness of outside counsel. For example, Alcon was represented Gibson Dunn, every bit as expensive as SAVA’s Orrick.

[C19 Science @DorianUpdate]

@Adrian_H Summary https://t.co/tzrLQUuPqQ

[C19 Science @DorianUpdate]

@bsilly3 @Adrian_H CUNY meeting unmasked

[C19 Science @DorianUpdate]

@Adrian_H @jesse_brodkin @mosquitobight @JaneDoe35299512 @ChrisRock002 @CTADconference More people looking at this week as in more Twitter attention this week or do you have knowledge of more authorities looking at the matter this week?

[Marc Lipsitch @mlipsitch]

So here's my take on the BU experiments. I know you can't say this on Twitter, but it is my current state of understanding, possibly imperfect, subject to revision with better understanding, and trying to make sense rather than condemn opponents.

[C19 Science @DorianUpdate]

@Adrian_H @champy_robert @MoralOverdraft @rdohnethook @JaneDoe35299512 @Nemo_is_NoOne @CassavaSciences @CTADconference @alzassociation @jpreventionalz1 @US_FDA Which is your poster? Does the study include original wet lab work as the above video implies? https://t.co/8ojbtLINPF

[Helen Branswell 🇨🇦 @HelenBranswell]

Scientists at Boston University have posted a preprint of work they've done on a chimeric SARS-2 virus. NIAID, which provided some of the grant money, has questions about why it wasn't informed about work that might be viewed as gain of function science.
https://t.co/epfq6kpjUm

[Eric Topol @EricTopol]

From outside the US, across the pond, data scientist @jburnmurdoch @FT
https://t.co/XVxfx5dESw
"Over the past 18 months, the politicisation of science may have directly cost as many as 60,000 American lives"

[C19 Science @DorianUpdate]

DeSantis & Florida are numnuts.

[Kristen Panthagani, MD, PhD @kmpanthagani]

Florida just announced the results of an analysis that they performed, saying the results show "an increased risk of cardiac-related death among men 18-39" for the mRNA vaccines, and recommend this group not receive these vaccines.

Is this justified? Let's look at the data...

[Nate @TornadoNate]

When I was a kid in Southern Illinois, we used to go to an apple orchard every fall to pick apples

It wasn’t like the u-pick places now. It wasn’t agritourism or particularly festive

You drove up to Holt’s and there was a big concrete slab with a tin roof behind the farmhouse

[C19 Science @DorianUpdate]

@SohrabAhmari Check back in two months. 🌬