Juanito Escarcha

Dr. Frost PhD

[USWBSI @USWBSI]

Tools available for fusarium head blight prediction include the USWBSI FHB Risk Tool. https://t.co/NbnXp8z1Bt

[Ruuj @RuujSs]

MIT published the complete graduate course on discrete stochastic processes for free.
Taught by Robert Gallager one of the most respected names in information theory.

It covers finite-state Markov chains, eigenvalues and eigenvectors of stochastic matrices, renewal theory, and martingales.
The mathematical foundation behind regime switching models used across quantitative finance.

Watch It Now & get ready for the article on Kalman Filter Tomorrow!

[Akos T. Kovacs @EvolvedBiofilm]

From an interesting observation to an experimental system on circadian gene expression in B. subtilis, published in @NatureComms from @MicroClockERC

The Bacillus subtilis circadian clock coordinates intricate spatiotemporal organisation
👉 https://t.co/u6JYGWvp9i
[1/n]🧵

[Nico @nicos_ai]

ADOBE ACROBAT ESTÁ ACABADO.

Alguien ha creado un editor de PDF gratis y open source que corre 100% en tu máquina y no sube ni un solo archivo.

Se llama Stirling-PDF.

Cada vez que editas un PDF online, tu archivo se sube al servidor de otro.

Tu NDA.
Tu extracto bancario.
Tu pasaporte escaneado.

Stirling-PDF lo procesa todo en local y lo borra en cuanto termina la tarea.

→ 50+ herramientas PDF en una sola interfaz
→ Unir, dividir, comprimir, convertir, rotar, reordenar
→ OCR integrado para hacer buscables los PDF escaneados
→ Contraseñas, marcas de agua, firmas y redacciones
→ API REST completa para automatizar
→ Corre en Docker en tu propio hardware

Adobe cobra 239$/año por Acrobat Pro.

Esto hace lo mismo por 0$.

• 81k estrellas en GitHub.
• 30M+ descargas.
• La app de PDF #1 de la plataforma.

100% open source.

Enlace abajo👇

[Eric Topol @EricTopol]

Yet another study shows a 24% reduced risk of dementia after the Shingles vaccine. This one in over 500,000 participants with a recent skilled nursing facility stay, adding to 4 huge natural experiments in 4 countries (US, Canada, Wales, and Australia)
https://t.co/TmYqwTB7IT @AnnalsofIM

[Akos T. Kovacs @EvolvedBiofilm]

A comment in @NatureComms for the use of defined microbial communities for microbial applications

I was glad to be involved in this highly collaborative discussions during online workshops last year, the thought from which are now published

https://t.co/t4BeyzQbYK

[Arnaud Bertrand @RnaudBertrand]

This is a very good example of how democracy works at a local level in China 👇

To explain succinctly, at every administrative level in China, they have a "people's congress" (人民代表大会 - rénmín dàibiǎo dàhuì).

At the county, district and township level, representatives are directly elected by voters in their constituencies. Above that (prefectural cities, provinces, and the National People's Congress) - representatives are elected by the congress one level below.

Depending on the location, local people's congresses have more or less oversight power on local spending, appointments, and policy.

Zhejiang province is one of the places in China where people's congresses have the most power after an official named Xi Jinping - you may have heard of the guy - established a framework called "do practical things for the people" (为民办实事 - wèi mín bàn shí shì) when he was provincial party secretary in the early 2000s.

What "do practical things for the people" established was a principle that local people's congress representatives should have a direct say in how local public money got spent. Over time, this evolved into a formal voting system where representatives vote on proposed government projects.

They just exercised this power in a major way: the Huangyan District People's Congress (黄岩区人大) in Taizhou, Zhejiang voted on 16 major government investment projects for 2026 but killed two of them on the spot - a sports center and an irrigation megaproject, totaling over a billion yuan - with roughly 80% voting against.

This doesn't mean these 2 projects are dead forever but they're sent back to the drawing board. The responsible departments have to address whatever concerns representatives raised, bring in experts for further review, and resubmit when they're ready.

This is a level of local democracy that many people will probably be surprised exists in China: it's genuine democratic oversight, they can actually block government spending, and the executive has to go back and try again.

It's also - and this is where China is complex - something that surprised many people in China.

As I mentioned above, not all people's congresses have this sort of power and the story generated a lot of national interest - with many national outlets writing about it, such as Guancha (https://t.co/Ad94EJH3vt) or The Paper (https://t.co/EPPcXQxXRV).

So much so that the Zhejiang People's Congress deleted their original WeChat post about it. We don't know why - the story wasn't suppressed since so many state media outlets carried it - but the Zhejiang People's Congress probably didn't love being the face of a national debate about why other provinces aren't doing this too, as it amounts to throwing shade on their peers. I genuinely don't know, just a hypothesis.

Anyhow, that's China in all its complexity and why sweeping narratives about it are always wrong: a country where elected local representatives can genuinely exercise oversight power over the government thanks to reforms initiated by Xi Jinping himself, and where mainstream media boast about it, but where the provincial organ that broke the story would rather avoid the publicity.

[Hugging Models @HuggingModels]

Gemma 4 12B Coder is here and it's a game changer for local code generation. This GGUF model packs Google's latest gemma-4 architecture into a compact 12B size, perfect for running on consumer hardware. It's optimized for reasoning and thinking, making it ideal for developers who want fast, private coding assistance without the cloud.

[ares. 🎧 @aresotik]

Anthropic publicó su prompting oficial para Claude.

24 minutos, gratis y directo de las personas que lo construyeron.

si usas Claude y no has visto esto, estás perdiendo el tiempo.

[Mindful Learning @MindfulL205]

Digital microfluidics: The art of controlling droplets with electricity

[Gonzalo Parra @GonzaParra_]

How to frustrate a plant pathogen??? 😍
https://t.co/vbW5gQKog9

[Nature Biotechnology @NatureBiotech]

Programmable, multiplexed and orthogonal gene control in bacteria with attenuated Cas13d systems https://t.co/6qo1QrQIvX

[good papers @paperperday]

Visualisation and Prediction of Phosphate Deficiency via Auto-Glowing Plant Bioluminescent Sensors
https://t.co/kVRob1BFCS

[Eric Topol @EricTopol]

Just published @NatureMedicine and presented @ASCO
Advanced, refractory solid cancers treated with a bispecific T cell engager (BiTE, Figure), Phase 1 trial, with or without Keytruda, in 61 patients. Some very favorable responses with "manageable safety profile"
https://t.co/MkzQXY1psA

[Plant Health Progress @planthealthprog]

PDMR: “Evaluation of New and Experimental Fungicides, Biologicals, and Natural Products for Botrytis Fruit Rot Management on Strawberry in San Luis Obispo, California, Late Season 2024,” by Kyle A. Blauer, Samantha Z. Simard, and Gerald J. Holmes: https://t.co/bGKesT0UQz

[James Albert 🐟 🇺🇦 @JamesAl0410008]

Over half of all soil eukaryotes are fungi, with notable contributions from protist groups like alveolates and amoebozoans, as well as some animal groups (nematodes, arthropods). One needs a good zoology textbook to fully understand the soils.

[Raj Rajnarayanan @RajlabN]

"Because early tests looked for the wrong strain of Ebola, we got false negatives and lost weeks of response time"

https://t.co/xviCaHZGew

[rcsb pdb 💉🧬💻🔬💊🌱🧠🦠 @buildmodels]

Try this new online training game from Leandro F. Estrozi designed for newcomers in structural biology, with a focus on cryo-EM and cryo-ET map interpretation: https://t.co/gxhQXmRPWL

[Satoshi Kawato 川戸 智 @KawatoSatoshi]

gbdrawのロゴを作りました。広葉樹林の地図記号...ではないです #gbdraw

[Max Nadeau @MaxNadeau_]

My biorisk colleagues put together this extremely specific and unusual set of projects. My main takeaway from this list was that there are whole classes of pandemics that our society basically never thinks about or prepares for, but it's fixable!

https://t.co/ctu2HKAThb