Senior Scientist @PMResearch_UHN
Consultant Hematologist @pmcancercentr
Assoc. Prof. University of Toronto
MBChB PhD FRACP FRCPA.
Science and coffee fan
Advocating for better medicines access in New Zealand. The Govt's arbitrary spending limit on medicines (at approx 1/3rd that of comparable nations) is strangling healthcare delivery for Kiwis. https://t.co/MUDDmCas77
Breaks my heart reading stories like this from a country I love. This poor chap can’t access proven, standard of care therapy for myeloma in NZ. The gulf between life saving medicines access either side of the Tasman just gets wider and wider…. https://t.co/8NePhTtoym
Myeloma families shouldn't have to be doing givealittles for medicines that are standard of care overseas. Please read the article - it includes comment on dara funding. https://t.co/yjCWod7JBG
@ninashah33 Thanks Nina for the super kind post.
I’m happy that there is an increasing acceptance that the way forward to cure involves eradicating these cells. Working together I’m optimistic that we can achieve that.
@gjmccaughan@MyelomaAust_MFA@MyelomaNZ Thanks Georgia! You’re so kind. It’s a pleasure to be back and am looking forward to working in the Australasian myeloma scene.
@adamcbest @BioBenBarwick Thinking that gun control won't reduce gun violence is like, I don't know.. like.. thinking that vaccines won't reduce disease.
@shanmugamlab @BioBenBarwick I was converted by our 1q findings…OXPHOS is super important in myeloma and a potential target. Someone needs to do a trial.
sciCNV: high-throughput paired profiling of transcriptomes and DNA copy number variations at single-cell resolution https://t.co/vr1L3bWNnL @scell_papers
Published today! Methods for dual profiling of DNA CNV and RNA in single cells. These improve (a) scRNA-seq normalization (b) CNV detection from RNA, enabling study of CNV effects on transcription at single cell level. https://t.co/cDaASnQx0b @PMResearch_UHN@SingleCellMedia
Delighted to report on the first highly selective GRK6 inhibitor. The fruits of a truly excellent collaboration with OICR. A paper that was long in the making. Thanks to all our co-authors.
Design, Synthesis, and Characterization of 4-Aminoquinazolines as Potent Inhibitors of the G Protein-Coupled Receptor Kinase 6 (GRK6) for the Treatment of Multiple Myeloma https://t.co/IXR9L1rrAQ