Dupree Lab

The plant cell wall biology group of Paul Dupree in the @Cambridge_Uni

[Dupree Lab @DupreeLab]

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[Dupree Lab @DupreeLab]

Proud that our scientific contributions are cited and have impact!

[Cambridge Biochemistry @CamBiochem]

Congratulations to Paul Dupree (@DupreeLab) on his selection as a @Clarivate #HighlyCitedResearcher for the eighth successive year. This is testament to the exceptional quality and impact of his research over many years: https://t.co/2I3bO9g0jf

[Dupree Lab @DupreeLab]

#glycotime

[Dupree Lab @DupreeLab]

https://t.co/Z3zm4cePbN Thanks @Jenny_Mortimer1 and Henrik Scheller for the insightful commentary on our recent work in @NewPhyt. We identified the missing ArapTs and GalTs for plant xylan synthesis. Bacteria may be adapting their GH30 xylanases to cleave these xylan structures!

[Dupree Lab @DupreeLab]

Original paper: https://t.co/vtUe6QdtHX

[Dupree Lab @DupreeLab]

Congratulations to Wout and John! Their great research on plant cell walls, especially lignin synthesis and diversity of structure, is recognised with this prestigious prize

[Cambridge Biochemistry @CamBiochem]

In @NewPhyt, Theodora Tryfona (@DupreeLab) and coauthors provide a better understanding of the molecular architecture of grass cell walls, opening new avenues to improve #cereals for food and the production of #bioenergy and #biomaterials. Read more: https://t.co/h3iIehtb0G

[Cambridge Biochemistry @CamBiochem]

The @SupplantCompany, which started in the Department and works closely with @DupreeLab,
has launched its revolutionary new pasta in the UK in the dining halls of Magdalene College (@magdalenealumni). It is healthier and better for the planet, more here: https://t.co/lt5N3vYONK

[Cambridge Biochemistry @CamBiochem]

Paul Dupree has been awarded a £1-million @innovateuk grant to work with the @SupplantCompany. The award enables the @DupreeLab to use their ground-breaking research to support the development of Supplant's healthier alternatives to sugar and starch: https://t.co/ZRDCdIRlXD

[Dupree Lab @DupreeLab]

Plant cell wall glycosyltransferases underpin the complex structure of dietary fibre. In our new work https://t.co/cVCGjoO8Y2, we show that β-xylosylated xyloglucan arose from the rapidly evolving GT47 family, while a promiscuous GH43 hydrolase permits its digestion in the gut.

[Dupree Lab @DupreeLab]

Wonderful news! We can’t wait to continue developing our plant cell wall architecture models using this amazing solid state NMR facility! #glycotime

[Warwick Physics @WarwickPhysics]

📢Prof. Steven Brown has been awarded £17M with consortium partners to procure the UK's most powerful Nuclear Magnetic Resonance (NMR) instrument at 1.2GHz. @NrfHf
Funded by @EPSRC, the national facility will enable applications from batteries to pharmaceuticals.
Find out more⬇️

[Dupree Lab @DupreeLab]

We are delighted our publications continue to be highly cited! Plant cell wall studies influence many aspects of our lives! #glycotime

[Eric Miska @ericmiska]

Same procedure as last year? @CamBiochem Steve Jackson @SPJacksonGroup and Paul Dupree @Reasonedviews feature again as highly cited researchers in their field! https://t.co/2JW0f48bkO

[Dupree Lab @DupreeLab]

We are delighted to contribute to this opportunity to discover how plant cell walls can enable development of new sustainable materials #glycotime

[Magda Titirici @titiricigroup]

Is official: Thrilled to be the PI on a £6.1M @EPSRC programme grant to develop the next generation of sustainable material, both bio-based and bio-inspired! Can't wait to start working with an amazing team! @imperialcollege @BristolUni @Cambridge_Uni
https://t.co/ApxdHmPxOi

[Dupree Lab @DupreeLab]

Our unexpected discovery will change views on plant cell wall composition and architecture! The structure of primary cell wall polysaccharides seems to be very important for plants! #glycotime

[The Plant Cell @ThePlantCell]

Eudicot primary cell wall glucomannan is related in synthesis, structure and function to xyloglucan #PlantSci @Dupreelab https://t.co/C6kJ9OyniE

[Dupree Lab @DupreeLab]

Congratulations to @H_TempleS and @KI55141505 (Konan) for winning best postdoc talk and best PhD poster presentation at the IX Cell Wall Research Conference #glycotime

[Dupree Lab @DupreeLab]

This Nature Research Briefing highlights the importance of our Golgi SAM transporter and pectin methylation study! @NaturePlants https://t.co/JHEX2Rti6c

[Dupree Lab @DupreeLab]

Our work discovering putative Golgi SAM transporters is now out in @NaturePlants! https://t.co/rSO4SqZFTO Using solid state NMR with @MeiHongLab we found egg box pectin structures in the plant cell wall. Egg box formation is influenced by methylation status! #glycotime

[Dupree Lab @DupreeLab]

@NaturePlants @MeiHongLab More details from @H_TempleS https://t.co/MvWQR3PXOp

[Henry Temple @H_TempleS]

I’m thrilled to see our work on the discovery of strong candidates for plant Golgi SAM transporters published in @NaturePlants! This work was done in the @DupreeLab in an exciting collaboration with the @MeiHongLab @OrellanaLab and Ray Dupree #glycotime https://t.co/Q95FokIEKB

[Dupree Lab @DupreeLab]

Our work discovering putative Golgi SAM transporters is now out in @NaturePlants! https://t.co/rSO4SqZFTO Using solid state NMR with @MeiHongLab we found egg box pectin structures in the plant cell wall. Egg box formation is influenced by methylation status! #glycotime

[Nature Plants @NaturePlants]

New Article: "Golgi-localized putative S-adenosyl methionine transporters required for plant cell wall polysaccharide methylation" https://t.co/d1i6RkUW36

Methylation occurs in the Golgi and relies on the import of SAM molecules into the Golgi lumen by transporters.

[Dupree Lab @DupreeLab]

7/7 In plants, GT47 enzymes are vital for cell wall synthesis. Our phylogenies show that many non-angiosperms possess additional GT47s that are closely related to animal EXTs. However, the fusion with GT64 appears to have arisen only at the outset of metazoan evolution.

[Dupree Lab @DupreeLab]

We’re thrilled that our work on EXTL3 is finally out in @NatureComms! The structure is a first for Golgi bi-domain GTs and the GT47 family. There are discoveries on plant GT47s too: a putative UDP-binding motif and a new subclade in lower plants https://t.co/I0AWIifCvS #glycotime

[Dupree Lab @DupreeLab]

6/7 Consistent with these features, and despite the presence of 10 mM UDP, we were unable to find density for UDP in the GT47 domain. The GT64 domain, however, binds UDP identically to murine EXTL2.